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Journal ArticleDOI

Platelet-derived growth factor: a promising therapeutic target for atrial fibrillation.

Céline Fiset
- 01 Jul 2013 - 
- Vol. 10, Iss: 7, pp 1052-1053
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This article is published in Heart Rhythm.The article was published on 2013-07-01. It has received 3 citations till now.

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A biolayer interferometry-based enzyme-linked aptamer sorbent assay for real-time and highly sensitive detection of PDGF-BB

TL;DR: A biolayer interferometry-based enzyme-linked aptamer sorbent assay (BLI-ELASA) was successfully established and can be easily adapted to detect other biomolecules in clinical samples, including viruses, pathogens and toxins, in a rapid, sensitive, high-throughput and real-time manner.
Journal ArticleDOI

A label-free electrochemical aptasensor based on the core-shell Cu-MOF@TpBD hybrid nanoarchitecture for the sensitive detection of PDGF-BB.

TL;DR: The hybridization of MOFs and COFs, together with the immobilization with the specific analyte targeted aptamer, provides a promising and propagable approach to prepare an aptasensor for the simple, sensitive, and selective detection of a specific biomarker in clinical diagnosis.
Journal ArticleDOI

Atrial fibrillation: the role of hypoxia-inducible factor-1-regulated cytokines.

TL;DR: In this paper, the authors highlight the association between HIF and some of its related cytokines with atrial fibrillation and provide an overview of the potential diagnostic benefits of using the mentioned cytokines as AF biomarkers.
References
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Journal ArticleDOI

New ideas about atrial fibrillation 50 years on

TL;DR: The prevailing model of atrial fibrillation involved multiple simultaneous re-entrant waves, but in light of new discoveries this hypothesis is now undergoing re-evaluation.
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2011 ACCF/AHA/HRS Focused Update on the Management of Patients With Atrial Fibrillation (Updating the 2006 Guideline) A Report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines

TL;DR: This work presents a meta-analyses of the FACC/FESC/FAHA double-blind, placebo-controlled, and sham drowning experiments that demonstrate the ability of these animals to understand each other and provide real-time information about each other's drowning experiences.
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Atrial fibrosis: mechanisms and clinical relevance in atrial fibrillation.

TL;DR: The current understanding of how atrial fibrosis creates a substrate for AF is reviewed, what is known about the mechanisms underlying fibrosis and its progression is summarized, and emerging therapeutic approaches aimed at attenuating structural remodeling to prevent AF are highlighted.
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2011 ACCF/AHA/HRS Focused Updates Incorporated Into the ACC/AHA/ESC 2006 Guidelines for the Management of Patients With Atrial Fibrillation A Report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines

TL;DR: This guideline was developed in conjunction with the European Society of Cardiology (ESC) and aims to improve the effectiveness of care, optimize patient outcomes, and favorably affect the overall cost of care by focusing resources on the most effective strategies.
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Cardiac fibroblast: the renaissance cell.

TL;DR: Insight is provided into the various properties of cardiac fibroblasts that helps illustrate their importance in maintaining proper cardiac function, as well as their critical role in the remodeling heart.