Journal ArticleDOI
Properties of mouse leukemia viruses. IX. Active and passive immunization of mice against Friend leukemia with isolated viral GP71 glycoprotein and its corresponding antiserum.
TLDR
Mice could be protected against Friend leukemia virus-induced leukemia by inoculation with the major viral glycoprotein GP71 or its antiserum.About:
This article is published in Virology.The article was published on 1975-07-01. It has received 96 citations till now. The article focuses on the topics: Friend leukemia & Mouse Leukemia Virus.read more
Citations
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Journal ArticleDOI
Characterization of envelope and core structural gene products of HTLV-III with sera from AIDS patients
W G Robey,B Safai,Stephen Oroszlan,L O Arthur,Matthew A. Gonda,Robert C. Gallo,Peter J. Fischinger +6 more
TL;DR: The techniques in this study can be used to define the extent of variability of the env gene product among different virus isolates and may identify the nature and patterns of the humoral immune response that lead to an immunologically protected state.
Journal ArticleDOI
Prevention of HIV-2 and SIVsm infection by passive immunization in cynomolgus monkeys.
Per Putkonen,Rigmor Thorstensson,Lili Ghavamzadeh,Jan Albert,Kerstin Hild,Gunnel Biberfeld,Erling Norrby +6 more
TL;DR: This paper showed that passively transferred antibodies can protect against a low-dose lentivirus challenge in a nonhuman primate against SIVsm infection in a cage of cynomolgus monkeys.
Journal ArticleDOI
Mouse leukemia: therapy with monoclonal antibodies against a thymus differentiation antigen.
TL;DR: Monoclonal antibodies against a thymus cell differentiation antigen (Thy-1.1) were effective in the therapy of a transplanted mouse leukemia and resulted in the cure of leukemia in a significant proportion of the treated animals.
Journal ArticleDOI
Shedding and interspecies type sero-reactivity of the envelope glycopolypeptide gp120 of the human immunodeficiency virus.
TL;DR: Two glycopolypeptides with molecular weights 160,000 and 120,000 (gp120) are regularly recognized by human immunodeficiency virus (HIV)-specific antisera in lysates of cells persistently infected with HIV.
Journal ArticleDOI
Nucleotide sequence of the envelope gene of Friend murine leukemia virus.
W. Koch,G. Hunsmann,R. Friedrich +2 more
TL;DR: It is suggested that this rigid and highly variable region of gp70 participates in infection by recognition of cell surface receptors and, in addition, might contribute to the different oncogenic spectra of murine leukemia viruses.
References
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Journal ArticleDOI
Properties of mouse leukemia viruses. VIII. The major viral glycoprotein of Friend leukemia virus. Seroimmunological, interfering and hemagglutinating capacities.
TL;DR: The purified major glycoprotein (GP 71) of Friend leukemia virus revealed type-specific as well as species-specific and interspecies antigenicities in various types of seroimmunological tests.
Journal ArticleDOI
Properties of mouse leukemia viruses: VII. The major viral glycoprotein of Friend leukemia virus. Isolation and physicochemical properties
TL;DR: The major viral glycoprotein of Friend leukemia virus was isolated by a procedure comprising density gradient centrifugation, Con A affinity chromatography, and Sephadex gel filtration and found to be pure by physicochemical and seroimmunological methods.
Journal ArticleDOI
Influence of Immunologic Hyperstimulation on Murine Viral Leukemogenesis
TL;DR: Mice inoculated with Rauscher leukemogenic virus, following a series of weekly injections of complete Freund’s adjuvant in combination with virus-unrelated antigens, showed increased survivals and delayed appearances of circulating nucleated erythrocytes characteristic of the leukemia.