Journal ArticleDOI
Reduction in fatal pulmonary embolism and venous thrombosis by perioperative administration of subcutaneous heparin. Overview of results of randomized trials in general, orthopedic, and urologic surgery.
TLDR
Most deep-vein thromboses are subclinical and resolve completely when mobility is restored, although some do produce permanent valvular damage and chronic venous insufficiency, and a few, however, may travel to the lungs and, depending on how much of the pulmonary circulation is.Abstract:
DURING prolonged general anesthesia and any period of limited mobility following surgery, thrombus formation may be initiated in the deep veins of the legs. Studies employing Radio-labeled fibrinogen or venography have revealed deep-vein thrombosis in 20 to 30 percent of patients who have undergone general surgery and in an even larger proportion of patients who have had orthopedic surgery.1 2 3 Most such thromboses are subclinical and resolve completely when mobility is restored, although some do produce permanent valvular damage and chronic venous insufficiency. A few, however, may travel to the lungs and, depending on how much of the pulmonary circulation is . . .read more
Citations
More filters
Journal ArticleDOI
Prevention of venous thromboembolism
Willitim Geerts,Joel C. Ray,Clifford W. Colwell,David Bergqvist,Graham F. Pineo,M. R. Lassen,John A. Heit +6 more
TL;DR: The risk factors for VTE among hospitalized patients are outlined, the efficacy and safety of alternative prophylaxis regimens are reviewed, and recommendations regarding the most suitable prophymic regimens based on the estimated risk are provided.
Journal ArticleDOI
Prevention of Venous Thromboembolism* American College of Chest Physicians Evidence- Based Clinical Practice Guidelines (8th Edition)
William H. Geerts,David Bergqvist,Graham F. Pineo,John A. Heit,Charles M. Samama,Michael R. Lassen,Clifford W. Colwell +6 more
TL;DR: This article discusses the prevention of venous thromboembolism (VTE) and is part of the Antithrombotic and Thrombolytic Therapy: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines (8th Edition).
Standards for the Diagnosis and Care of Patients with Chronic Obstructive Pulmonary Disease
Bartolome R. Celli,Gordon L. Snider,John E. Heffner,Brian Tiep,Irwin Ziment,Barry J. Make,Sidney Braman,Gerald Olsen,Yancy Y. Phillips +8 more
TL;DR: Values below this suggest that further studies, such as split func-tion assessment by quantitative lung scintigraphy and exercisetesting, are warranted, and that all elective surgery Prophylaxis against deep venous throm-bosis should be given before most procedures that will require postoperative bed rest or significantly reduce mobility.
Journal ArticleDOI
Prevention of Venous Thromboembolism : The Seventh ACCP Conference on Antithrombotic and Thrombolytic Therapy
William H. Geerts,Graham F. Pineo,John A. Heit,David Bergqvist,Michael R. Lassen,Clifford W. Colwell,Joel G. Ray +6 more
TL;DR: This article discusses the prevention of venous thromboembolism (VTE) and is part of the Seventh American College of Chest Physicians Conference on Antithrombotic and Thrombolytic Therapy: Evidence-Based Guidelines.
Journal ArticleDOI
Prevention of VTE in Nonsurgical Patients: Antithrombotic Therapy and Prevention of Thrombosis, 9th ed: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines
Yngve Falck-Ytter,Charles W. Francis,Norman A. Johanson,Catherine Curley,Ola E. Dahl,Sam Schulman,Thomas L. Ortel,Stephen G. Pauker,Clifford W. Colwell +8 more
TL;DR: In this article, the authors focus on optimal prophylaxis to reduce postoperative pulmonary embolism and DVT following major orthopedic surgery, and suggest the use of low-molecular-weight heparin in preference to the other agents we have recommended as alternatives.
References
More filters
Journal ArticleDOI
Beta blockade during and after myocardial infarction: an overview of the randomized trials
TL;DR: The aim has been not only to review the 65-odd randomized beta blocker trials but also to demonstrate that when many randomized trials have all applied one general approach to treatment, it is often not appropriate to base inference on individual trial results.
Journal ArticleDOI
Why do we need some large, simple randomized trials?
Journal ArticleDOI
Prevention of venous thrombosis and pulmonary embolism in injured patients. A trial of anticoagulant prophylaxis with phenindione in middle-aged and elderly patients with fractured necks of femur.
Simon Sevitt,N.G. Gallagher +1 more
Journal ArticleDOI
A randomized controlled trial of a low-molecular-weight heparin (enoxaparin) to prevent deep-vein thrombosis in patients undergoing elective hip surgery.
Alexander G.G. Turpie,Mark Levine,Jack Hirsh,Cedric J. Carter,Richard M. Jay,Peter Powers,Maureen Andrew,Russell D. Hull,Michael Gent +8 more
TL;DR: Prophylaxis with fixed-dose PK10169 heparin is effective and safe for patients undergoing elective hip replacement and the observed hemorrhagic rate was 4 percent in each treatment group.
Journal Article
Recurrent dislocation of the shoulder.
TL;DR: Recurrent Dislocation of the Shoulder: An Inquiry into the Mechanism and its Applications in Psychiatry.
Related Papers (5)
Prevention of venous thromboembolism in general surgical patients. Results of meta-analysis.
G. P. Clagett,Joan S. Reisch +1 more