Relationship between anxiety, depression, and morbidity in adult asthma patients
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TLDR
It is suggested that reported symptoms may be misleading and unreliable because they may reflect non-asthma factors that cannot be expected to respond to changes in asthma treatment.Abstract:
BACKGROUND Symptoms of disease reported by patients reflect the effects of the disease process within the individual and the person9s physical and mental ability to tolerate or otherwise cope with the limitations on their functioning. This study examines the relationship between asthma symptoms, disease severity, and psychological status in patients being managed in routine primary healthcare settings. METHODS One hundred and fourteen subjects from four GP practices, two inner city and two suburban, were studied. Symptoms were assessed by means of the Asthma Quality of Life questionnaire (AQLQ) and a locally devised Q score, and psychological status with the Hospital Anxiety and Depression (HAD) scale. Spirometric values and details of current asthma treatment (BTS asthma guidelines treatment step) were recorded as markers of asthma severity. RESULTS Symptoms as measured by AQLQ correlated with peak expiratory flow ( r S = 0.40) and with BTS guidelines treatment step ( r S = 0.25). Similarly, the Q score correlated with peak expiratory flow ( r S = 0.44) and with BTS guidelines treatment step ( r S = 0.42). Similar levels of correlation of forced expiratory volume in one second (FEV 1 ) with symptoms were reported. HAD anxiety and depression scores also correlated to a similar extent with these two symptom scores, but there was hardly any correlation with lung function. Logistic regression analysis showed that HAD scores help to explain symptom scores over and above the effects of lung function and BTS guidelines treatment step. Symptoms, depression, and anxiety were higher for inner city patients while little difference was observed in objective measures of asthma. CONCLUSIONS Asthma guidelines suggest that changing levels of symptoms should be used to monitor the effectiveness of treatment. These data suggest that reported symptoms may be misleading and unreliable because they may reflect non-asthma factors that cannot be expected to respond to changes in asthma treatment.read more
Citations
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British guideline on the management of asthma: A national clinical guideline
Graham Douglas,Bernard Higgins,Neil Barnes,Anne Boyter,Sherwood Burge,Christopher J Cates,Gary Connett,Jon Couriel,Paul Cullinan,Sheila Edwards,Erica Evans,Monica Fletcher,Christopher E.M. Griffiths,Liam Heaney,Michele Hilton Boon,Steve Holmes,Ruth McArthur,C Nelson-Piercy,Martyn R Partridge,James Y. Paton,Ian D. Pavord,Elaine Carnegie,Hilary Pinnock,Safia Qureshi,Colin F. Robertson,Michael D. Shields,John O. Warner,John H. White +27 more
TL;DR: These guidelines have been replaced by British Guideline on the Management of Asthma.
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The association of depression and anxiety with medical symptom burden in patients with chronic medical illness.
TL;DR: Accurate diagnosis of comorbid depressive and anxiety disorders in patients with chronic medical illness is essential in understanding the cause and in optimizing the management of somatic symptom burden.
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Disability and Poor Quality of Life Associated With Comorbid Anxiety Disorders and Physical Conditions
TL;DR: Anxiety disorders are independently associated with several physical conditions in the community, and this comorbidity is significantly associated with poor quality of life and disability.
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The relationship between anxiety disorders and physical disorders in the U.S. National Comorbidity Survey.
TL;DR: Among specific anxiety disorders, posttraumatic stress disorder, panic attacks, and agoraphobia were more likely to be associated with specific physical disorders than generalized anxiety disorder, social phobia, or simple phobia.
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Influence of comorbid conditions on asthma
TL;DR: A systematic evaluation and an appropriate treatment of asthma-associated comorbid conditions should be part of asthma management, particularly for severe disease.
References
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Journal ArticleDOI
The Hospital Anxiety and Depression Scale.
A. S. Zigmond,R. P. Snaith +1 more
TL;DR: It is suggested that the introduction of the scales into general hospital practice would facilitate the large task of detection and management of emotional disorder in patients under investigation and treatment in medical and surgical departments.
Journal ArticleDOI
Lung volumes and forced ventilatory flows
TL;DR: Assessing the total lung capacity is indispensable in establishing a restrictive ventilatory defect or in diagnosing abnormal lung distensibility, as may occur in patients …
Journal Article
Lung volumes and forced ventilatory flows. Report Working Party Standardization of Lung Function Tests, European Community for Steel and Coal. Official Statement of the European Respiratory Society.
Journal ArticleDOI
Determining a minimal important change in a disease-specific quality of life questionnaire
TL;DR: The observation that the minimal important difference is consistent across domains and for both improvement and deterioration will facilitate interpretation of results of studies examining quality of life.
Journal ArticleDOI
Measuring Quality of Life in Asthma
TL;DR: It is concluded that the Asthma Quality of Life Questionnaire has good measurement properties and that it is valid as both an evaluative and a discriminative instrument and should be considered for inclusion in all asthma studies.