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Showing papers in "Chest in 2006"


Journal ArticleDOI
01 Jul 2006-Chest
TL;DR: The Global Initiative for Asthma has outlined a six-point patient management plan to address the effective handling of the increased number of patients in primary care, focusing on patient education, written treatment plans, and ongoing communication and review with patients and their providers.

1,271 citations


Journal ArticleDOI
01 Jan 2006-Chest
TL;DR: An American College of Chest Physicians task force formulated the criteria for a grading system to be utilized in all ACCP guidelines that included simplicity and transparency, explicitness of methodology, and consistency with current methodological approaches to the grading process.

1,189 citations


Journal ArticleDOI
01 Jan 2006-Chest
TL;DR: Subgroup analyses suggest the risk may be greater in African Americans compared with Caucasian subjects and whether this risk is due to factors including but not limited to a physiologic treatment effect, genetic factors, or patient behaviors leading to poor outcomes remains unknown.

1,108 citations


Journal ArticleDOI
01 Sep 2006-Chest
TL;DR: It was showed that BMI has significant effects on all of the lung volumes, and the greatest effects were on FRC and ERV, which occurred at BMI values < 30 kg/m2, which will assist clinicians when interpreting PFT results in patients with normal airway function.

874 citations


Journal ArticleDOI
01 Mar 2006-Chest
TL;DR: PAH is common in advanced cases of IPF and significantly impacts survival and might be an important adjunct in monitoring disease progression, triaging for transplantation, and guiding therapy.

770 citations


Journal ArticleDOI
01 Mar 2006-Chest
TL;DR: Patients with COPD are markedly inactive during and after hospitalization for an AE, and efforts to enhance physical activity should be among the aims of the disease management during and following the AE periods.

623 citations


Journal ArticleDOI
Rob Horne1
01 Jul 2006-Chest
TL;DR: Clinicians must be prepared to work in an ongoing partnership with patients to ensure that they are offered a clear rationale as to why ICS are necessary and to address their concerns about potential adverse effects.

542 citations


Journal ArticleDOI
01 May 2006-Chest
TL;DR: In this article, the authors identified 67 studies with 123 patient groups having 50,208 patients followed for a total of 57,154.7 patient-years and found that patients who have received anticoagulation therapy spend a significant proportion of their time with an INR out of the therapeutic range.

501 citations


Journal ArticleDOI
01 Sep 2006-Chest
TL;DR: Those whose Berlin questionnaire scores indicated a high risk for OSA were more likely to report subjective sleep problems, a negative impact of sleep on quality of life, and a chronic medical condition than those who were at lower risk.

476 citations


Journal ArticleDOI
01 Sep 2006-Chest
TL;DR: Compared to CT and PET, EBUS-TBNA has a high sensitivity as well as specificity for mediastinal and hilar lymph node staging in patients with lung cancer.

463 citations


Journal ArticleDOI
01 Jun 2006-Chest
TL;DR: In this article, the authors identify impaired efferocytosis as a contributor to chronic inflammation and identify new disease biomarkers, as well as novel therapeutic approaches, which may ultimately direct us toward the identification of new diseases biomarkers.

Journal ArticleDOI
01 May 2006-Chest
TL;DR: A serum NT-proBNP level of > or = 1,400 pg/mL was found to be useful in identifying patients with poor long-term prognosis both in the whole studied group and in the IPAH subgroup.

Journal ArticleDOI
01 Jul 2006-Chest
TL;DR: The incidence of chronic thromboembolic pulmonary hypertension after the first episode of objectively confirmed pulmonary embolism was about 1%, and a diagnosis of CTPH was confirmed in two patients with idiopathic PE.

Journal ArticleDOI
01 Nov 2006-Chest
TL;DR: HIV infection was an independent risk factor for COPD, when determined either by ICD-9 codes or patient self-report, and health-care providers should be aware of the increased likelihood of COPD among their HIV-positive patients.

Journal ArticleDOI
01 May 2006-Chest
TL;DR: The adult-based anatomic pathway, which involves the investigation and treatment of patients with asthma, GERD, and UACS first is largely unsuitable for use in the management of chronic cough in young children as the common etiologies of Chronic cough in children are different from those in adults.

Journal ArticleDOI
01 Jan 2006-Chest
TL;DR: In a patient with chronic cough, ACE inhibitors should be considered as wholly or partially causative, regardless of the temporal relation between the initiation of ACE inhibitor therapy and the onset of cough.

Journal ArticleDOI
01 Jul 2006-Chest
TL;DR: PAH associated with SLE or MCTD might respond to a treatment combining glucocorticosteroids and cyclophosphamide, and patients with a lower baseline NYHA functional class and better baseline pulmonary hemodynamics were more likely to benefit from immunosuppressive therapy.

Journal ArticleDOI
01 Sep 2006-Chest
TL;DR: Current research indicates that neurocognitive sequelae following critical illness are common, may be permanent, and are associated with impairments in daily function, decreased quality of life, and an inability to return to work.

Journal ArticleDOI
01 Nov 2006-Chest
TL;DR: In this article, the fraction of exhaled nitric oxide (Feno) is elevated in subjects with asthma and atopy, and it has been proposed to be a noninvasive marker of airway inflammation.

Journal ArticleDOI
01 Apr 2006-Chest
TL;DR: Early feeding significantly reduces ICU and hospital mortality based mainly on improvements in the sickest patients, despite being associated with an increased risk of ventilator-associated pneumonia developing.

Journal ArticleDOI
01 Jan 2006-Chest
TL;DR: The emergence of resistance to adamantanes and recently oseltamivir while H5N1 vaccines are still at the developmental stage of phase I clinical trial are causes for grave concern and the to-be pandemic strain may have little cross immunogenicity to the presently tested vaccine strain.

Journal ArticleDOI
01 Nov 2006-Chest
TL;DR: A variety of histopathologic patterns can be seen in patients with pSS-associated ILD, including nonspecific interstitial pneumonia (NSIP) and organizing pneumonia (OP) and those with UIP, who tended to have progression of lung disease.

Journal ArticleDOI
01 May 2006-Chest
TL;DR: Treatment patterns for VAP vary widely from institution to institution, and the overall mortality rate remains unacceptably high, but the deescalation of therapy in VAP patients appears to be associated with a reduction in mortality, which is an association that warrants further clinical study.

Journal ArticleDOI
01 Dec 2006-Chest
TL;DR: Among routinely measured clinical variables, RSBI, positive fluid balance 24 h prior to extubation, and pneumonia at the initiation of ventilation were the best predictors ofextubation failure, however, the combined predictive ability of these variables was weak.

Journal ArticleDOI
01 Feb 2006-Chest
TL;DR: With effective emergency medicine/critical care collaboration, it is demonstrated that EGDT end points can reliably be achieved in real-world sepsis resuscitation.

Journal ArticleDOI
01 Mar 2006-Chest
TL;DR: For instance, this article found that 53% of patients believed they only had asthma when they were having symptoms, what they call the no symptoms, no asthma belief, and those receiving oral steroids all or most of the time or with symptoms most days had half the odds of having this belief.

Journal ArticleDOI
01 Apr 2006-Chest
TL;DR: The superDimension/Bronchus system (SDBS) is safe and effective in navigating to peripheral lung lesions located beyond the optic limits of a standard flexible bronchoscope and obtaining biopsy specimens.

Journal ArticleDOI
01 Feb 2006-Chest
TL;DR: The hypothesis that bacteria and viruses may modulate this heterogeneity and that interactions between bacterial and viral infection may affect changes in airway bacterial load and the clinical features and inflammatory responses of exacerbations in patients with COPD is examined.

Journal ArticleDOI
01 Jul 2006-Chest
TL;DR: The risk factors and prevalence for OSA in India are similar to those in the West, which is contrary to the findings of some previous reports, which had a strong inclusion bias.

Journal ArticleDOI
01 Jan 2006-Chest
TL;DR: In this article, the authors present evidence-based guidelines to assist general and specialist medical practitioners in the evaluation and management of children who present with chronic cough, which is subdivided into specific cough and nonspecific cough (cough associated with other symptoms and signs suggestive of an associated or underlying problem).