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Open AccessJournal ArticleDOI

Relationship of the Pulmonary Artery End-Diastolic Pressure to the Left Ventricular End-Diastolic and Mean Filling Pressures in Patients With and Without Left Ventricular Dysfunction

Raul E. Falicov, +1 more
- 01 Jul 1970 - 
- Vol. 42, Iss: 1, pp 65-73
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TLDR
In the presence of LV dysfunction and elevated LV EDP, PAEDP correlated well with PAWMP, but failed to represent LVEDP accurately, while PA a wave pressure closely reflected LVEDp except when PVR was markedly increased.
Abstract
The relationship of the left ventricular end-diastolic pressure (LVEDP) and the pulmonary arterial "wedge" mean pressure (PAWMP) to the pulmonary artery end-diastolic pressure (PAEDP) was investigated by cardiac catheterization in 71 subjects. Pressure records were obtained simultaneously or immediately consecutively. In 15 subjects with normal LV function (LVEDP, 4 to 12 mm Hg) PAEDP was within 3 mm Hg of LVEDP (r = 0.70, P < 0.01) and within 3 mm Hg of PAWMP (r = 0.69, P < 0.01) in every instance. In 56 patients with LV dysfunction (LVEDP, 12 to 55 mm Hg), PAEDP was lower than LVEDP in 42, equal to LVEDP in six, and higher than the LVEDP in eight, who were in atrial fibrillation or had increased pulmonary vascular resistance (PVR). PAEDP correlated closely with PAWMP (r = 0.92, P < 0.001). In 30 patients with LV dysfunction in sinus rhythm, an a wave was identified in the PA pressure tracing (PA a) prior to systole which coincided in time and magnitude to the PAW a wave and was considered to represent r...

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Journal ArticleDOI

Medical Therapy of Acute Myocardial Infarction by Application of Hemodynamic Subsets

TL;DR: The goals of prompt and effective therapy of disordered cardiac function and preservation of ischemic muscle, although far from achieved, have been greatly advanced in the past several years by the widespread use of hemodynamic monitoring.
Journal ArticleDOI

Relationship of Pulmonary Artery to Left Ventricular Diastolic Pressures in Acute Myocardial Infarction

TL;DR: PA pressures only provided reliable information about the level of pulmonary venous pressure, and therefore measurement of LVDP (pre-a and EDP) yielded information not only about pulmonary edema, but also about LV performance.
Journal ArticleDOI

Pulmonary edema related to changes in colloid osmotic and pulmonary artery wedge pressure in patients after acute myocardial infarction.

TL;DR: Observations indicate that both increases in pulmonary capillary pressure and decreases in colloid osmotic pressure may follow the onset of pulmonary edema, and decline in colloids osmatic pressure and especially the reduction in colloidal osmosis-hydrostatic capillary Pressure gradient may favor transudation of fluid into the lungs.
Journal ArticleDOI

Left ventricular hemodynamics in anterior and inferior myocardial infarction

TL;DR: Initial hemodynamics were studied in 50 patients with acute myocardial infarction classified according to anterior or inferior location, and there was a significant difference when initial left ventricular filling pressure, stroke index, heart rate and stroke work index were considered together.
References
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Journal ArticleDOI

Time Relationship of Dynamic Events in the Cardiac Chambers, Pulmonary Artery and Aorta in Man

TL;DR: The results obtained by permutation of simultaneous pressure recordings confirm the classical observations made in dogs.
Journal ArticleDOI

An Intensive Coronary Care Area

Hughes W. Day
- 01 Oct 1963 - 
TL;DR: It is believed that separated areas are desirable, but patient load studies are necessary before a hospital embarks on separate programs, and combined Acute Intensive Care-Intensive Coronary Care Areas are financially practicable.
Journal ArticleDOI

The Gradient in Pressure Across the Pulmonary Vascular Bed During Diastole

TL;DR: Within defined limits friction across the pulmonary vascular bed is so small that a state of pressure equilibrium exists at the end of diastole, when the limits are met clinically, the pressures in the pulmonary artery and in the left ventricle at the start of diastsole are identical.
Journal ArticleDOI

Premature mitral valve closure: a hemodynamic explanation for absence of the first sound in aortic insufficiency.

TL;DR: The phenomenon of premature mitral valve closure is described in three patients with severe aortic insufficiency and related to absence of the first heart sound and it often implies a grave prognosis.
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