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Resonance Raman spectroscopy and mechanics of single red blood cell manipulated by optical tweezers
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The article was published on 2007-01-01 and is currently open access. It has received 5 citations till now. The article focuses on the topics: Optical tweezers & Resonance Raman spectroscopy.read more
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Journal ArticleDOI
Raman Tweezers as a Diagnostic Tool of Hemoglobin-Related Blood Disorders
TL;DR: The success of resonance Raman spectroscopy for thalassemia detection reported in this review provide an interesting starting point to explore the application of a Raman Tweezers system in the analysis of several blood disorders.
Journal ArticleDOI
Raman Microspectroscopy Analysis in the Treatment of Acanthamoeba Keratitis
Giulia Rusciano,Paola Capriglione,Giuseppe Pesce,Salvatore Del Prete,Gilda Cennamo,David Di Cave,Luciano Cerulli,Antonio Sasso +7 more
TL;DR: This work uses Raman microspectroscopy to analyse in vitro a single Acanthamoeba cell in cystic phase, investigating the effect of polyhexamethylene biguanide at the single-cell level and demonstrating that Raman spectroscopy, in conjunction with standard multivariate analysis methods, allows discriminating between live and dead Acanthamas, which is fundamental to optimizing patients’ treatment.
Journal ArticleDOI
Optical tweezers: a non-destructive tool for soft and biomaterial investigations
Alessandro Magazzù,D. Spadaro,Maria Grazia Donato,Rania Sayed,E. Messina,Cristiano D’Andrea,Antonino Foti,Barbara Fazio,Maria Antonia Iatì,A. Irrera,Rosalba Saija,Pietro Giuseppe Gucciardi,Onofrio M. Maragò +12 more
TL;DR: Optical tweezers are a key technique for trapping and contactless manipulation of particles at the micro-and nanoscale that can exert and sense forces from hundreds of piconewton down to few femtonewton as discussed by the authors.
Phase-sensitive detection in Raman Tweezers:biological applications
De Luca,Anna Chiara +1 more
TL;DR: In this paper, the authors proposed a new method, termed Raman Tweezers (RT), which employs optical tweezers to trap a microsized object in order to confine its motion for Raman spectroscopic analysis.
DissertationDOI
Non-equilibrium dynamics of biological matter in microfluidic environments - from red blood cell flickering to conformational transitions of actin filaments
TL;DR: A straightforward, self-filling microfluidic device that autonomously separates and isolates single RBCs directly from unprocessed human blood samples and confines them in diffusion-controlled microchambers by solely exploiting their unique intrinsic properties and the provision of important insights into the RBC's biomedical and biophysical properties is introduced.