Journal ArticleDOI
Risk factors for diabetic retinopathy: a population-based study in Rochester, Minnesota.
David J. Ballard,L. J. Melton,M. S. Dwyer,J. C. Trautmann,Chu-Pin Chu,William M. O'Fallon,Pasquale Palumbo +6 more
TLDR
A proportional hazards model identified the following risk factors for diabetic retinopathy in patients with non-insulin-dependent diabetes mellitus (NIDDM): elevated initial fasting blood glucose level, marked obesity, and earlier age at onset of diabetes.Abstract:
Retinopathy is an important sequela of diabetes mellitus, but clinical risk factors for this condition have rarely been assessed in a geographically defined population. In this population-based study, the 1135 Rochester, Minnesota, residents with diabetes mellitus initially diagnosed between 1945 and 1969 (incidence cohort) were followed through their complete medical records in the community to January 1, 1982. Because most of the cases of diabetic retinopathy in Rochester residents developed in patients with non-insulin-dependent diabetes mellitus (NIDDM), risk factors for diabetic retinopathy were examined in this group (N = 1031). A proportional hazards model identified the following risk factors for diabetic retinopathy in NIDDM: elevated initial fasting blood glucose level, marked obesity, and earlier age at onset of diabetes. Stratified analyses indicated that duration of diabetes was also significantly associated with an increased risk of retinopathy. Two secular trends, increasing detection of "mild" NIDDM and decreasing risk of diabetic retinopathy, had a major effect on retinopathy risk assessment. These data also suggest that insulin therapy is not an independent risk factor for diabetic retinopathy.read more
Citations
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Journal ArticleDOI
The Wisconsin epidemiologic study of diabetic retinopathy. VI: Retinal photocoagulation
TL;DR: Seventy-two percent of eyes of younger onset and 45% of Eyes of older onset persons that had received panretinal photocoagulation treatment were found to have incomplete regression of retinal new vessels, and in approximately half of these eyes severe proliferative retinopathy (Diabetic Retinopathy Study High Risk Characteristics [DRS-HRC]) was present.
Journal ArticleDOI
The Wisconsin Epidemiologic Study of Diabetic Retinopathy: XVII. The 14-year incidence and progression of diabetic retinopathy and associated risk factors in type 1 diabetes
TL;DR: The data suggest relatively high 14-year rates of progression of retinopathy and incidence of macular edema and suggest that a reduction of hyperglycemia and hypertension may result in a beneficial decrease in the progression to proliferative Retinopathy.
Journal ArticleDOI
The Wisconsin Epidemiologic Study of Diabetic Retinopathy: XXII the twenty-five-year progression of retinopathy in persons with type 1 diabetes.
TL;DR: These data show relatively high 25-year cumulative rates of progression of DR and incidence of PDR and the lower risk of prevalent PDR in more recently diagnosed persons possibly reflects improvement in care over the period of the study.
Journal ArticleDOI
The Wisconsin Epidemiologic Study of Diabetic Retinopathy: IX. Four-Year Incidence and Progression of Diabetic Retinopathy When Age at Diagnosis Is Less Than 30 Years
TL;DR: This paper performed a population-based study in southern Wisconsin of insulin-taking diabetic persons diagnosed before 30 years of age and found that the incidence of proliferative retinopathy rose with increasing duration until 13 to 14 years of diabetes, thereafter remaining between 14% and 17%.
Journal ArticleDOI
The prevalence of and factors associated with diabetic retinopathy in the Australian population.
Robyn J. Tapp,Jonathan E. Shaw,C Alex Harper,Maximilian de Courten,Beverley Balkau,Daniel J. McCarty,Daniel J. McCarty,Hugh R. Taylor,Timothy A Welborn,Paul Zimmet +9 more
TL;DR: Regular screening for diabeticretinopathy and more aggressive management of modifiable risk factors could reduce the numbers of people who develop vision-threatening retinopathy.
References
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