Journal ArticleDOI
Selenium mediated dose-inhibition of 7,12-dimethylbenz[a]anthracene-induced transformation of mammary cells in organ culture
TLDR
In this article, the influence of selenium on transformation of mammary cells, induced by 7,12-dimethylbenz[a]anthracene (DMBA), was assessed in organ culture of the whole mammary glands from BALBc female mice.About:
This article is published in Cancer Letters.The article was published on 1982-11-01. It has received 30 citations till now. The article focuses on the topics: 7,12-Dimethylbenz[a]anthracene & Organ culture.read more
Citations
More filters
Journal ArticleDOI
Dietary carcinogens and anticarcinogens Oxygen radicals and degenerative diseases
TL;DR: Dietary intake of natural antioxidants could be an important aspect of the body's defense mechanism against these agents of cancer and other age-related diseases.
Journal ArticleDOI
Arsenic, selenium, boron, lead, cadmium, copper, and zinc in naturally contaminated rocks: A review of their sources, modes of enrichment, mechanisms of release, and mitigation strategies.
Carlito Baltazar Tabelin,Toshifumi Igarashi,Mylah Villacorte-Tabelin,Ilhwan Park,Einstine M. Opiso,Mayumi Ito,Naoki Hiroyoshi +6 more
TL;DR: This review summarized all available studies in the literature about the factors and processes crucial in the enrichment, release, and migration of the most commonly encountered hazardous and toxic elements in naturally contaminated geological materials to focus on naturally contaminated rocks.
Book ChapterDOI
Chemical carcinogenesis: from animal models to molecular models in one decade.
TL;DR: The rasH gene (and perhaps other members of the ras gene family) appears to be a common target for coding sequence mutations in the initiation of carcinogenesis in several organ sites and species by specific carcinogens.
Journal Article
Cigarette Smoking, Cytochrome P450 1A1 Polymorphisms, and Breast Cancer Risk in the Nurses' Health Study
Naoko Ishibe,Susan E. Hankinson,Graham A. Colditz,Donna Spiegelman,Walter C. Willett,Frank E. Speizer,Karl T. Kelsey,David J. Hunter +7 more
TL;DR: The hypothesis that cigarette smoking early in life is a modifiable cause of breast cancer in a subpopulation of genetically susceptible women in a case-control study nested within the Nurses' Health Study is compatible.
Journal ArticleDOI
The need for a reassessment of the safe upper limit of selenium in drinking water.
Marco Vinceti,Catherine M. Crespi,Francesca Bonvicini,Francesca Bonvicini,Carlotta Malagoli,Margherita Ferrante,Sandra Marmiroli,Saverio Stranges +7 more
TL;DR: Results of recent epidemiologic studies suggest the need to reassess the safe upper limit in drinking water of selenium, a metalloid with both toxicological and nutritional properties, and suggest reduction to 1 μg/l in order to adequately protect human health.
References
More filters
Journal ArticleDOI
Antioxidants and cancer. Part VI. Selenium and age-adjusted human cancer mortality.
TL;DR: In the states with high selenium levels, there was significantly lower mortality in both males and females from several types of cancer, particularly the environmental problem indicators, such as gastrointestinal and urogenital types ofcancer.
Journal ArticleDOI
Relationship of Selenium to Cancer. I. Inhibitory Effect of Selenium on Carcinogenesis
Biochemical function of selenium and its relation to vitamin E.
TL;DR: A scheme is proposed, based on oxidant damage and its prevention, which accounts for the interaction between selenium, vitamin E, unsaturated lipids, sulfur-containing amino acids, and cell damaging agents such as oxidant stressors and toxicants such as silver and tri-o-cresyl phosphate.
Journal ArticleDOI
Selenium is an essential trace nutrient for growth of WI-38 diploid human fibroblasts
TL;DR: The trace element selenium is essential for clonal growth of diploid fibroblasts from human fetal lung (WI-38) in media containing small amounts of serum protein, and appears to be a source of seenium in most culture media.
Book ChapterDOI
Role of selenium in the chemoprevention of cancer.
TL;DR: Postulated roles or mechanisms that may be involved in the inhibition of carcinogenesis by Se are a reduction in the mutagenicity of cancer causing chemical, effects on carcinogen metabolism, and protection against oxidative damages.