Severe psoriasis--oral therapy with a new retinoid.

doi:10.1159/000250839

Journal ArticleDOI

Severe psoriasis--oral therapy with a new retinoid.

T. Fredriksson, +1 more

- 01 Jan 1978 -

Dermatology

- Vol. 157, Iss: 4, pp 238-244

Chats0

TLDR

Ro 10--9359 proved to be an extremely potent antipsoriatic drug and a more than 90% reduction of psoriatic lesions could be seen in 10 patients out of 20 after 4-8 weeks of treatment.

Abstract:

Ro 10–9359 is a retinoic acid derivative, selected for study because of a better tolerance than retinoic acid, shown in animal experiments. Doses of 25 mg b.i.d., 25 mg t.i.d. and 50 mg b.i.d. were ad

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Classification criteria for psoriatic arthritis: Development of new criteria from a large international study

William J. Taylor, +5 more

- 01 Aug 2006 -

Arthritis & Rheumatism

TL;DR: The CASPAR criteria are simple and highly specific but less sensitive than the Vasey and Espinoza criteria and are confirmed as the validity of clinical diagnosis as the gold standard definition of "case"-ness.

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Efficacy and safety of ustekinumab, a human interleukin-12/23 monoclonal antibody, in patients with psoriasis: 76-week results from a randomised, double-blind, placebo-controlled trial (PHOENIX 1)

Craig L. Leonardi, +8 more

- 17 May 2008 -

The Lancet

TL;DR: Ustekinumab seems to be efficacious for the treatment of moderate-to-severe psoriasis; dosing every 12 weeks maintains efficacy for at least a year in most patients.

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Journal ArticleDOI

A Meta-Analytic Review of the Common-Sense Model of Illness Representations

Martin S. Hagger, +1 more

- 01 Jan 2003 -

Psychology & Health

TL;DR: A meta-analysis of empirical studies adopting Leventhal, Meyer and Nerenz's (1980) Common Sense Model (CSM) of illness representations is presented in this paper, where the average corrected intercorrelation matrix for the sample of studies showed that the CSM illness cognition dimensions of consequences, control/cure, identity and timeline followed a logical pattern supporting their construct and discriminant validity across illness types.

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Journal ArticleDOI

Etanercept in the treatment of psoriatic arthritis and psoriasis: a randomised trial

Philip J. Mease, +5 more

- 29 Jul 2000 -

The Lancet

TL;DR: Etanercept offers patients with psoriatic arthritis and psoriasis a new therapeutic option for control of their disease.

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Journal ArticleDOI

Etanercept as monotherapy in patients with psoriasis

Craig L. Leonardi, +6 more

- 20 Nov 2003 -

The New England Journal of Medicine

TL;DR: The treatment of psoriasis with etanercept led to a significant reduction in the severity of disease over a period of 24 weeks, paralleled by improvements in global assessments by physicians and the patients and in quality-of-life measures.

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References

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Book

Introduction to Statistical Analysis

Wilfrid J. Dixon, +1 more

TL;DR: In this paper, the authors introduce statistical analysis and introduce the concept of statistical analysis in statistical analysis, and propose a framework for statistical analysis for the analysis of statistical data in the literature.

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Therapeutic effects of an aromatic retinoic acid analog on chemically induced skin papillomas and carcinomas of mice

Werner Bollag

- 01 Nov 1974 -

European Journal of Cancer

TL;DR: The investigation has proven that the antipapilloma effect is not strictly linked with hypervitaminosis A, and raises hopes for finding compounds with an even better therapeutic ratio, useful in the experimental and clinical prophylaxis and therapy of premalignant and malignant epithelial lesions.

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Journal ArticleDOI

Systemic use of a new retinoid with and without local dithranol treatment in generalized psoriasis.

C.E. Orfanos, +1 more

- 01 Jul 1976 -

British Journal of Dermatology

TL;DR: A 20-year-old woman, who gave little trouble undl 3 years ago, became more active, new lesions appeared, especially on her scalp, and the older ones enlarged, and she flared severely over the face and neck, and when seen in July she was both unsightly and depressed.

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