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Journal ArticleDOI

Shear dependence of effective cell volume as a determinant of blood viscosity.

Shu Chien
- 22 May 1970 - 
- Vol. 168, Iss: 3934, pp 977-979
TLDR
The viscosity of suspensions of human erythrocytes was measured over a wide range of shear rates, and the macrorheological data were correlated with the micror heological behavior of ery throatcytes and rigid particles.
Abstract
The viscosity of suspensions of human erythrocytes (normal cells in plasma, normal cells in Ringer's solution containing albumin, and hardened cells in Ringer's solution containing albumin) was measured over a wide range of shear rates, and the macrorheological data were correlated with the microrheological behavior of erythrocytes and rigid particles. The formation of rouleaux increases the effective volume of erythrocytes as a result of (i) the increase in axial ratio and (ii) the limitation of deformation of individual erythrocytes. The effective cell volume is the fundamental determinant of blood viscosity.

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Citations
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Journal ArticleDOI

Blood flow in arteries

TL;DR: The study of arterial blood flow will lead to the prediction of individual hemodynamic flows in any patient, the development of diagnostic tools to quantify disease, and the design of devices that mimic or alter blood flow.
Journal ArticleDOI

Fluid Mechanics of Vascular Systems, Diseases, and Thrombosis

TL;DR: New convection models have been developed to predict clinical from platelet thrombosis in diseased arteries, and future hemodynamic studies should address the complex mechanics of flow-induced, large-scale wall motion and convection of semisolid particles and cells in flowing blood.
Journal ArticleDOI

Rheological aspects of thrombosis and haemostasis: basic principles and applications. ICTH-Report--Subcommittee on Rheology of the International Committee on Thrombosis and Haemostasis.

TL;DR: Etude des debits liquidiens a travers les vaisseaux cylindriques, du comportement de debit du sang, des concepts de base du transport de masse dans le sang, et la nomenclature.
Journal ArticleDOI

Flow-induced clustering and alignment of vesicles and red blood cells in microcapillaries.

TL;DR: This model combines a particle-based mesoscale simulation technique for the fluid hydrodynamics with a triangulated-membrane model and shows that already at very low HT, the deformability of RBCs implies a flow-induced cluster formation above a threshold flow velocity.
References
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Journal ArticleDOI

The formation of emulsions in definable fields of flow

TL;DR: The physical and chemical condition of emulsions of two fluids which do not mix has been the subject of many studies, but very little seems to be known about the mechanics of the stirring processes which are used in making them.
Journal ArticleDOI

The viscosity of a concentrated suspension of spherical particles

TL;DR: In this paper, the authors extended the viscosity equation for an infinitely dilute suspension of spheres to apply to a suspension of finite concentration, and made use of a functional equation which must be satisfied if the final viscosities is independent of the sequence of stepwise additions of partial volume fractions of the spheres to the suspension.
Journal ArticleDOI

Rheology of blood

E. W. Errill
TL;DR: Rheology 863 Experimental Methods, Rheological Tests or Simplified Testing, and Effect of Additives on Blood Rheology.
Journal ArticleDOI

Fluid Drop-Like Transition of Erythrocytes under Shear

TL;DR: Red cells dispersed in a continuous medium of high viscosity possess the flow properties of fluid drops, while under shear they become progressively deformed into prolate ellipsoids, their long axis aligned parallel to the flow direction.
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