Journal ArticleDOI
Single-molecule detection of yeast cytochrome c by Surface-Enhanced Raman Spectroscopy
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TLDR
The statistical analysis of the spectra from immobilised samples seems to indicate dynamical processes involving the reorientational of the heme with respect to the metal surface, consistent with the approaching of single molecule regime.About:
This article is published in Biophysical Chemistry.The article was published on 2005-01-01. It has received 86 citations till now. The article focuses on the topics: Raman spectroscopy & Surface-enhanced Raman spectroscopy.read more
Citations
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Progress in plasmonic engineering of surface-enhanced Raman-scattering substrates toward ultra-trace analysis.
Gary A. Baker,David S. Moore +1 more
TL;DR: This review describes advances made toward the application of surface-enhanced Raman scattering (SERS) in sensitive analysis and diagnostics and focuses on the extensive progress made in designing innovative soluble, supported, and ordered SERS-active nano-architectures to harness the potential of this technique toward solving current and emerging analytical tasks.
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Surface-enhanced Raman scattering for protein detection
TL;DR: This review outlines the development of SERS-based methods for proteins with particular focus on the proposed protein-mediated Sers-active substrates and their applications in label-free and Raman dye-labeled protein detection.
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Multiplex in vitro detection using SERS
TL;DR: This review focuses on the strengths of SERS for the detection of target molecules from complex mixtures and the clinical relevance of recent work combining SERS with multiplexed detection of biological targets.
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Deterministic aperiodic arrays of metal nanoparticles for surface-enhanced Raman scattering (SERS)
TL;DR: The ability to rigorously design lithographically fabricated DA arrays of metal nanoparticles enables the optimization and control of highly localized plasmonic fields for a variety of chip-scale devices, such as more reproducible SERS substrates, label-free bio-sensors and non-linear elements for nano-plasmonics.
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Plasmonic Nanogalaxies: Multiscale Aperiodic Arrays for Surface-Enhanced Raman Sensing
Ashwin Gopinath,Svetlana V. Boriskina,W. Ranjith Premasiri,Lawrence D. Ziegler,Björn M. Reinhard,Luca Dal Negro +5 more
TL;DR: Using rigorous generalized Mie theory calculations and a combined top-down/bottom-up nanofabrication approach, approximately 10(8) spatially averaged, reproducible SERS enhancement in deterministic aperiodic arrays of Au nanoparticles with different length scales are designed and experimentally demonstrated.
References
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Journal ArticleDOI
Probing Single Molecules and Single Nanoparticles by Surface-Enhanced Raman Scattering
Shuming Nie,Steven R. Emory +1 more
TL;DR: In this article, surface-enhanced Raman scattering was used to detect single molecules and single nanoparticles at room temperature with the use of surface enhanced Raman, and the intrinsic Raman enhancement factors were on the order of 10 14 to 10 15, much larger than the ensemble-averaged values derived from conventional measurements.
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Single Molecule Detection Using Surface-Enhanced Raman Scattering (SERS)
Katrin Kneipp,Katrin Kneipp,Yang Wang,Yang Wang,Harald Kneipp,Harald Kneipp,Lev T. Perelman,Lev T. Perelman,Irving Itzkan,Irving Itzkan,Ramachandra R. Dasari,Ramachandra R. Dasari,Michael S. Feld,Michael S. Feld +13 more
TL;DR: In this article, the first observation of single molecule Raman scattering was made using a single crystal violet molecule in aqueous colloidal silver solution using one second collection time and about $2.
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Raman spectra of pyridine adsorbed at a silver electrode
TL;DR: In this article, Ramaman spectroscopy has been employed for the first time to study the role of adsorption at electrodes, and it has been possible to distinguish two types of pyridine adaption at a silver electrode.
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Adsorption and surface-enhanced Raman of dyes on silver and gold sols
P. C. Lee,Dan Meisel +1 more
TL;DR: Several negatively charged dyes were investigated for their possible adsorption on the surface of colloidal particles and those dyes that were found to adsorb on the particles were then checked for surface enhancement of Raman scattering.
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Electronics using hybrid-molecular and mono-molecular devices
TL;DR: ‘mono-molecular’ electronics, in which a single molecule will integrate the elementary functions and interconnections required for computation, is proposed.