Journal ArticleDOI
Sleep disruption in cystic fibrosis.
TLDR
Some early evidence suggests that nocturnal supportive ventilation provides physiologic benefits as well as improvements in quality of life in patients with cystic fibrosis.About:
This article is published in Medical Hypotheses.The article was published on 2008-12-01. It has received 11 citations till now. The article focuses on the topics: Hypoventilation.read more
Citations
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Journal ArticleDOI
Melatonin improves sleep and reduces nitrite in the exhaled breath condensate in cystic fibrosis--a randomized, double-blind placebo-controlled study.
Claudia de Castro-Silva,Veralice Meireles Sales de Bruin,Geanne M. A. Cunha,Deuzilane Muniz Nunes,C. A. M. Medeiros,Pedro Felipe Carvalhedo de Bruin +5 more
TL;DR: Melatonin administration reduces nitrite levels in EBC and improves sleep measures in clinically stable CF patients, and the failure of melatonin to reduce isoprostane levels may have been a result of the low dose ofmelatonin used as a treatment.
A resiliency perspective of the lived experience of parenting infants and young children with cystic fibrosis in the context of early lung disease surveillance
TL;DR: Pathways that enable adaptation to paediatric chronic disease in the context of early surveillance were identified using a resiliency framework of family adjustment and adaption and contribute to current conceptualisations of parenting children with chronic conditions undergoing modern interventions that aim to delay disease.
Journal ArticleDOI
Expression and distribution of cystic fibrosis transmembrane conductance regulator in neurons of the spinal cord.
TL;DR: The finding of widespread and abundant expression of CFTR in the spinal cord suggests that this molecule may be significant in the normal function and pathology of the spinal Cord.
Journal ArticleDOI
Fatigue in cystic fibrosis: A novel prospective study investigating subjective and objective factors associated with fatigue
TL;DR: Female patients with CF received antibiotics for more days than male patients withCF, and a close correlation was found between the fatigue score and the GHQ domain-specific scores and with the total score; p < 0.0001 for Patients with CF and p = 0.001 for control.
Journal ArticleDOI
Evaluation of selected insomnia predictors in adolescents and young adults with cystic fibrosis.
TL;DR: Assessment of the incidence of insomnia in adolescents and young adults with cystic fibrosis and its impact on the quality of life found anxiety and depression are factors that increase the risk of insomnia.
References
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Book
Cystic Fibrosis
TL;DR: Advances in understanding and treatment of cystic fibrosis are summarized, focusing on pulmonary disease, which accounts for most morbidity and deaths.
Journal ArticleDOI
Pathophysiology of Adult Obstructive Sleep Apnea
Danny J. Eckert,Atul Malhotra +1 more
TL;DR: The potential for novel treatment strategies, based on an improved understanding of the underlying pathophysiology, is discussed and some of the pathophysiological characteristics associated with OSA that may modulate disease severity are illustrated.
Journal Article
Non-invasive mechanical ventilation for cystic fibrosis patients--a potential bridge to transplantation
TL;DR: Nasal intermittent positive pressure ventilation appears to be a useful bridge to transplantation when a patient suddenly deteriorates and gives them a chance of survival for a few more days or even weeks during which time an urgent search for donor organs can be made.
Journal ArticleDOI
Nocturnal Nasal IPPV Stabilizes Patients with Cystic Fibrosis and Hypercapnic Respiratory Failure
TL;DR: It is believed nIPPV offers an effective therapeutic approach for patients with end-stage CF in hypercapnic respiratory failure and may be particularly advantageous for those awaiting heart-lung transplant.
Journal ArticleDOI
Nocturnal ventilatory support in patients with cystic fibrosis: comparison with supplemental oxygen
TL;DR: It is concluded that noninvasive positive pressure ventilation improves sleep-related hypoxaemia and hypercapnia in severe cystic fibrosis patients without affecting sleep.