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Solid-liquid equilibrium of nicotinamide in water-ethanol and water-propylene glycol mixtures

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TLDR
In this paper, the Apelblat model showed a good correlation in both solvent systems, the best predictive fit model, and the experimental results were compared with a correlative thermodynamic model, three activity coefficient models (Wilson, UNIQUAC, NRTL), and with literature data.
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This article is published in Journal of Molecular Liquids.The article was published on 2022-01-01. It has received 2 citations till now. The article focuses on the topics: UNIQUAC & Non-random two-liquid model.

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Application of a multilayer physical model for the critical analysis of the adsorption of nicotinamide and propranolol on magnetic-activated carbon

TL;DR: The model allows stating that the adsorption of both the pharmaceutical compounds occurs via the formation of one or two layers on MAC adsorbent, the propranolol showing a higher tendency to form multiple layers.
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Influence of physicochemical properties and structure of mixed solvents propylene glycol – macrogol 400 on their in vitro release

TL;DR: In this paper , the density and dynamic viscosity of the mixed solvents propylene glycol (PG) and macrogol 400 (M400) were studied over the entire concentration range at temperatures from 293.15 to 313.15 K.
References
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Journal ArticleDOI

Hydrogen bonding interaction of ascorbic acid with nicotinamide: Experimental and theoretical study

TL;DR: In this article, the interactions of ascorbic acid (AA) with nicotinamide (NA) were investigated by cyclic voltammetry (CV), 1H nuclear magnetic resonance (1H NMR), density functional theory (DFT) and atoms in molecules (AIM) analysis.
Journal ArticleDOI

Solid-liquid equilibrium of paracetamol in water-ethanol and water-propylene glycol mixtures

TL;DR: In this paper, the authors determined paracetamol solid-liquid equilibrium in temperatures from 20 to 50°C for two solvent systems: water - ethanol and water - propylene glycol (PG), by refractometry method.
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Particle Characterization by X‐Ray Powder Diffraction

TL;DR: In this paper, X-ray diffraction was used to characterize internal particle parameters including crystal structure, crystallite size and microstrain for cocrystallization of pharmaceutical ingredients by ball milling and supercritical processes.
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What is the stability of nicotinamide in water?

The stability of nicotinamide in water was determined by studying its solid-liquid equilibrium in water-ethanol and water-propylene glycol mixtures.