Book ChapterDOI
Solute Diffusion in Hydrophilic Network Structures
Nicholas A. Peppas,Steven R. Lustig +1 more
- pp 57-84
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The article was published on 2019-08-15. It has received 41 citations till now.read more
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Journal ArticleDOI
Modeling of drug release from delivery systems based on hydroxypropyl methylcellulose (HPMC).
TL;DR: The present article is a comprehensive review of the current state of the art of mathematical modeling drug release from HPMC-based delivery systems and discusses the crucial points of the most important theories.
Journal ArticleDOI
Physicochemical foundations and structural design of hydrogels in medicine and biology.
TL;DR: This review discusses the molecular structure, dynamic behavior, and structural modifications of hydrogels as well as the various applications of these biohydrogels.
Journal ArticleDOI
Controlled release of proteins from dextran hydrogels
TL;DR: The release of three model proteins from hydrogels varying in water content and degree of GMA-substitution was studied and it was shown that the release of the proteins was independent of the degree ofGMA substitution of gels at high equilibrium water contents.
Release kinetics concepts and applications
TL;DR: A few of the various models used by researchers to study the release profile are explained in this review which includes the Higuchi model, which describes the drug release from a matrix system and the Weibull equation which describes drug dissolution and release from dosage forms.
Journal ArticleDOI
Understanding and Predicting Drug Delivery from Hydrophilic Matrix Tablets Using the “Sequential Layer” Model
TL;DR: The “sequential layer” model can be used to elucidate the swelling and drug release behavior from hydrophilic matrix tablets and to simulate the effect of the device geometry on the drug release patterns, which can facilitate the development of new pharmaceutical products.