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Stereochemical control of yeast reductions. 1. Asymmetric synthesis of L-carnitine
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This article is published in Journal of the American Chemical Society.The article was published on 1983-09-01. It has received 304 citations till now. The article focuses on the topics: Carnitine.read more
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Recent developments in asymmetric reduction of ketones with biocatalysts
TL;DR: In this article, a review of recent advances in the asymmetric reduction of ketones by biocatalysts is presented, with a discussion on recent developments in methodologies to control enantioselectivities of catalytic reactions.
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Dehydrogenases for the synthesis of chiral compounds
Werner Hummel,Maria-Regina Kula +1 more
TL;DR: Redox reactions are important steps in the metabolism and energy conversion of living cells and a number of coenzymes are involved: ferrodoxins, lipoic acid, NADH/NADPH, NADP(H), flavins and cytochromes.
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Microbial Asymmetric Catalysis—Enantioselective Reduction of Ketones [New Synthetic Methods (45)]
Charles J. Sih,Ching-Shih Chen +1 more
TL;DR: The present progress report deals with the basic concepts that govern enantioselectivity of enzymes and intact cells and strategies to control the stereochemical course of microbial reductions of carbonyl compounds and the relationship of substrate structure to enantiOSElectivity.
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Chiral Compounds Synthesized by Biocatalytic Reductions [New Synthetic Methods (51)]
TL;DR: The productivity numbers of compounds synthesized by the methods described in this review are often 10- to 100-fold higher than those of substances obtained by conventional techniques.