Journal ArticleDOI
Subcutaneous Sarcoma as an Index of Carcinogenic Potency
P Grasso,L Goldberg +1 more
About:
This article is published in Journal of Occupational and Environmental Medicine.The article was published on 1967-05-01. It has received 12 citations till now.read more
Citations
More filters
Journal ArticleDOI
Implanted depleted uranium fragments cause soft tissue sarcomas in the muscles of rats.
TL;DR: The results indicate that DU fragments of sufficient size cause localized proliferative reactions and soft tissue sarcomas that can be detected with radiography in the muscles of rats.
Journal ArticleDOI
Implications for human health.
TL;DR: To analyze the implications for human health, the toxicologist requires four sets of data: the results of toxicity and other studies in animals; quantitative data on actual or potential human exposure; whatever information is available on effects of exposure in man; and the statistical extrapolations from the dose-response relationships in animals to the much lower levels of human exposure.
Journal ArticleDOI
Evaluation of the Carcinogenic Potential of Insulin Glargine (LANTUS) in Rats and Mice
TL;DR: There were no neoplastic findings to indicate that insulin glargine had a systemic carcinogenic potential in mice or rats, and the distribution of subcutaneous malignant fibrous histiocytomas found at the injection site were not dose-dependent.
Journal ArticleDOI
Proliferative and Non-Proliferative Lesions of the Rat and Mouse Soft Tissue,Skeletal Muscle and Mesothelium
Peter Greaves,Luc Chouinard,Heinrich Ernst,Lars Mecklenburg,Ingrid M. Pruimboom-brees,Matthias Rinke,Susanne Rittinghausen,Stephane Thibault,Jasmin von Erichsen,Toshinori Yoshida +9 more
TL;DR: A widely accepted and utilized international harmonization of nomenclature for lesions in soft tissues, skeletal muscle and mesothelium in laboratory animals will decrease confusion among regulatory and scientific research organizations in different countries and provide a common language to increase and enrich international exchanges of information among toxicologists and pathologists.
Journal ArticleDOI
Growth effects of insulin and insulin analogues.
TL;DR: In these studies, inclusion of [B10-Asp] insulin would be a valuable link to the existing evidence on proliferation of mammary tissue in rodents, and may require definition of patient groups who would benefit from targeted monitoring.
References
More filters
Journal ArticleDOI
Implanted depleted uranium fragments cause soft tissue sarcomas in the muscles of rats.
TL;DR: The results indicate that DU fragments of sufficient size cause localized proliferative reactions and soft tissue sarcomas that can be detected with radiography in the muscles of rats.
Journal ArticleDOI
Implications for human health.
TL;DR: To analyze the implications for human health, the toxicologist requires four sets of data: the results of toxicity and other studies in animals; quantitative data on actual or potential human exposure; whatever information is available on effects of exposure in man; and the statistical extrapolations from the dose-response relationships in animals to the much lower levels of human exposure.
Journal ArticleDOI
Evaluation of the Carcinogenic Potential of Insulin Glargine (LANTUS) in Rats and Mice
TL;DR: There were no neoplastic findings to indicate that insulin glargine had a systemic carcinogenic potential in mice or rats, and the distribution of subcutaneous malignant fibrous histiocytomas found at the injection site were not dose-dependent.
Journal ArticleDOI
Proliferative and Non-Proliferative Lesions of the Rat and Mouse Soft Tissue,Skeletal Muscle and Mesothelium
Peter Greaves,Luc Chouinard,Heinrich Ernst,Lars Mecklenburg,Ingrid M. Pruimboom-brees,Matthias Rinke,Susanne Rittinghausen,Stephane Thibault,Jasmin von Erichsen,Toshinori Yoshida +9 more
TL;DR: A widely accepted and utilized international harmonization of nomenclature for lesions in soft tissues, skeletal muscle and mesothelium in laboratory animals will decrease confusion among regulatory and scientific research organizations in different countries and provide a common language to increase and enrich international exchanges of information among toxicologists and pathologists.
Journal ArticleDOI
[Carcinogenic activity of 13 aryldialkyl triazenes in BD-rats (author's transl)].
TL;DR: In this article, 13 1-Aryl-3,3-dialkyltriazenen zeigten 10 Triazene starke carcinogene Wirkung an BD-Ratten.
Related Papers (5)
Distribution and Growth-Potency of Cells in a Transplantable Sarcoma
Paul A. Zahl,Marion L. Drasher +1 more