Synthesis of Reversible Oxygen Complex of Polymeric Hemochrome
Eishun Tsuchida,Kenji Honda +1 more
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TLDR
Iron—protoporphyrin IX was bound to poly(vinylpyridine) and poly(vinylimidazole) at the axial site of the iron atom, so that an oxygen complex remained stable even in an aqueous solution.Abstract:
Iron—protoporphyrin IX was bound to poly(vinylpyridine) and poly(vinylimidazole) at the axial site of the iron atom. The equilibrium constant for the complexation of heme with the polymeric ligand is 102 times as large as that of the monomeric analogue. Such a polymeric hemochrome can take up molecular oxygen (O2) more rapidly than does the corresponding monomeric hemochrome. The degree of oxygen saturation of the polymer complex is appreciably higher than that of the monomer complex.The rate constant of oxygenation in water (ka\\simeq10 sec−1) is much larger than that in an organic solvent (ka\\simeq10−4sec−1). The rate constant (ka) at the adsorption step is appreciably affected by the conformational change of the polymer ligand; ka is enhanced by about 10 times under the optimal conditions.On the other hand, the rate constant (kd) at the decomposition step of the oxygen complex is drastically affected by the environment around an active site. Upon adding an appropriate agent such as a salt, poly electrolyte, or surface-active agent, kd decreased drastically with increasing concentration of additives, so that an oxygen complex remained stable even in an aqueous solution.read more
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Syntheses of Ruthenium(II)–Poly(4-vinylpyridine) Complexes and Their Spectroscopic Studies
TL;DR: In this article, the Ru(II)-poly(4-vinylpyridine) complexes, [Ru(bpy)2(PVP)2]Cl2 and [Ru[bpy]2 (PVP)(py)]Cl2, have been synthesized and compared spectroscopically with the monomeric [Ru{bpy}2(py)-cl2 complex, where py is pyridine, bpy is 2,2′-bipyridine.
Journal ArticleDOI
A novel poly[(N-vinylimidazole)-co-(1-pyrenylmethyl methacrylate)] ferric complex with fluorescence and superparamagnetism
TL;DR: In this paper, a VI-co-PyMMA copolymer with 1-chlorobutane and FeCl3 in succession is presented, which exhibits a balance of the properties with a fluorescence quantum yield of 0.13 and a magnetic susceptibility of 16.1 × 10−6 emu g−1.
Journal ArticleDOI
Cooperative reactions of poly-L-lysine-heme complex with molecular oxygen, carbon monoxide, or cyanide ion.
TL;DR: The interaction of the alpha-helical poly-L-lysine-heme complex with molecular oxygen, carbon monoxide, or cyanide ion was studied and the cooperative parameter was found to be 2.1.0, indicating a cooperative interaction between hemes situated on a cylindricalalpha-helix of poly- lysine.
Journal ArticleDOI
Towards an electrochemically modulated chromatographic stationary phase
TL;DR: A tentative chemical coupling procedure suitable for covalent immobilization of heme onto a conductive glassy carbon electrode via a polyethylene glycol spacer arm is developed as a necessary first step towards the development of an electrochemical chromatography system.
References
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Journal ArticleDOI
Reversible oxygen adduct formation in ferrous complexes derived from a picket fence porphyrin. Model for oxymyoglobin
Journal ArticleDOI
Pyridinate Complexes of Some Metallo-derivatives of Tetraphenylporphine and Tetraphenylchlorin1
J. R. Miller,G. D. Dorough +1 more
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The Electronic Structure of Protoheme Proteins: III. CONFIGURATION OF THE HEME AND ITS LIGANDS
J. Peisach,J. Peisach,William E. Blumberg,William E. Blumberg,Beatrice A. Wittenberg,Beatrice A. Wittenberg,Jonathan B. Wittenberg,Jonathan B. Wittenberg +7 more
TL;DR: In this paper, the electronic configurations of the heme groups and their associated ligands are described, and a nomenclature describing the electronic configuration of heme and its associated ligand is presented, which specifies for each compound, the d electron configuration, the structure of the sixth ligand of the Heme iron atom, and the oxidation state of the compound.