Journal ArticleDOI
Terbium chelate for use as a label in fluorescent immunoassays
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TLDR
Human serum albumin has been labelled with a terbium complex by means of a reagent prepared from the bis-cyclic anhydride of diethylenetriamine pentaacetic acid and p-aminosalicylic acid, which combines high fluorescent intensity with stability at high dilution.Abstract:
Human serum albumin has been labelled with a terbium complex by means of a reagent prepared from the bis-cyclic anhydride of diethylenetriamine pentaacetic acid and p-aminosalicylic acid. This reagent combines high fluorescent intensity with stability at high dilution (10–9M). The fluorescent conjugate so produced has been used in a simple fluoroimmunoassay, using human serum albumin as a model analyte.read more
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Time-Resolved Fluorescence of Lanthanide Probes and Applications in Biotechnology
TL;DR: The relaxation of excited molecular states is often followed by the emission of light as mentioned in this paper, which happens either by fluorescence emission or by nonradiative internal processes, referred to as intersystem crossing.
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Radioactive Main Group and Rare Earth Metals for Imaging and Therapy
Thomas I. Kostelnik,Chris Orvig +1 more
TL;DR: Fundamental concepts of drug design and applications are introduced, with particular emphasis on bifunctional chelators (BFCs), which ensure secure consolidation of the radiometal and targeting vector and are integral for optimal drug performance.
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Enzymatically amplified time-resolved fluorescence immunoassay with terbium chelates.
TL;DR: An ultrasensitive, enzymatically amplified, time-resolved fluorescence immunoassay with a terbium chelate as the detectable moiety with excellent precision, and it seems to be highly suited for automated, sensitive, and rapid Immunoassays.
Journal ArticleDOI
Making sense of Lanthanide Luminescence
TL;DR: The luminescence of trivalent lanthanide ions has found applications in lighting, lasers, optical telecommunications, medical diagnostics, and various other fields and two recent developments in the field of luminescent materials are addressed.
Journal ArticleDOI
The lanthanides as luminescent probes in investigations of biochemical systems
TL;DR: A review of the luminescence properties of lanthanides, their role as structural and analytical probes and the application of Lanthanide complexes in fluoroimmunological and nucleic acid hybridization assays is presented in this article.