Journal ArticleDOI
The association of the sodium "setpoint" to interdialytic weight gain and blood pressure in hemodialysis patients.
M. L. Keen,F. A. Gotch +1 more
TLDR
These data suggest that interdialytic weight gain in individual patients may be associated with the use of dialysate Na+ concentration in excess of the patient's desired Na+ “setpoint”.Abstract:
IntroductionHemodialysis patients lack the normal mechanisms to regulate body water volume and osmolality The dialysis treatment is expected to adequately regulate both body water volume and body N...read more
Citations
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Journal ArticleDOI
Predialysis serum sodium level, dialysate sodium, and mortality in maintenance hemodialysis patients: the Dialysis Outcomes and Practice Patterns Study (DOPPS).
Manfred Hecking,Angelo Karaboyas,Rajiv Saran,Ananda Sen,Walter H. Hörl,Ronald L. Pisoni,Bruce M. Robinson,Gere Sunder-Plassmann,Friedrich K. Port +8 more
TL;DR: Lower serum sodium levels are associated with certain hemodialysis patient characteristics and higher adjusted risk of death and may be related to intradialytic cardiovascular stability, and deserves further study.
Journal ArticleDOI
Dialysate Sodium Concentration and the Association with Interdialytic Weight Gain, Hospitalization, and Mortality
Manfred Hecking,Angelo Karaboyas,Rajiv Saran,Ananda Sen,Masaaki Inaba,Hugh C. Rayner,Walter H. Hörl,Ronald L. Pisoni,Bruce M. Robinson,Gere Sunder-Plassmann,Friedrich K. Port +10 more
TL;DR: In the absence of randomized prospective studies, the benefit of reducing IDWG by decreasing DNa prescriptions should be carefully weighed against an increased risk for adverse outcomes.
Journal ArticleDOI
Significance of Interdialytic Weight Gain versus Chronic Volume Overload: Consensus Opinion
Manfred Hecking,Angelo Karaboyas,Marlies Antlanger,Rajiv Saran,Volker Wizemann,Charles Chazot,Hugh C. Rayner,Walter H. Hörl,Ronald L. Pisoni,Bruce M. Robinson,Gere Sunder-Plassmann,Ulrich Moissl,Peter Kotanko,Nathan W. Levin,Marcus D. Säemann,Kamyar Kalantar-Zadeh,Friedrich K. Port,Peter Wabel +17 more
TL;DR: The present authors agree that discriminating between volume overload and IDWG will likely lead to a more appropriate management of fluid withdrawal during dialysis, and recommend objective measures of volume status beyond mere evaluations of IDWWG.
Journal ArticleDOI
A brief review of intradialytic hypotension with a focus on survival.
TL;DR: Evidence suggests that IDH causes acute reversible segmental myocardial hypoperfusion and contractile dysfunction (myocardial stunning), which can result in long‐term loss of myocardia contractility, leading to premature death, and a paradigm shift to its approach is urgently needed.
Journal ArticleDOI
Dialysate sodium, serum sodium and mortality in maintenance hemodialysis
TL;DR: The relationship between serum and dialysate sodium and mortality appears to be variable and further research is warranted to determine the biological mechanisms of these associations and to re-examine total body sodium handling in hemodialysis.
References
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Journal ArticleDOI
Clinical consequences of an individualized dialysate sodium prescription in hemodialysis patients
Flavio M. De Paula,Aldo J. Peixoto,Luciano V. Pinto,David Dorigo,Pedro J.M. Patricio,Sergio F.F. Santos +5 more
TL;DR: An individualized Na(+) dialysate based on predialysis plasma Na(+) levels decreases thirst, IDWG, HD-related symptoms, and pre-HD BP (in patients with uncontrolled BP at baseline).
Journal ArticleDOI
Long-term survival rates in haemodialysis patients treated with strict volume control
Mehmet Ozkahya,Ercan Ok,Huseyin Toz,Gulay Asci,Soner Duman,Ali Basci,Timur Köse,E.J. Dorhout Mees +7 more
TL;DR: The large majority of the patients had low-normal BP after long periods of treatment and showed the lowest mortality, favouring the view that target BP should be lower than advised by most authors.
Journal ArticleDOI
Dietary salt restriction and reduction of dialysate sodium to control hypertension in maintenance haemodialysis patients.
TL;DR: This work has demonstrated were long hours of overnight dialysis on a Kiil that it is possible to lower blood pressure and reduce dialyser with a cuprophan membrane and the importance of salt restriction as a requirement for regime.
Journal ArticleDOI
A critical evaluation of ultrasound measurement of inferior vena cava diameter in assessing dry weight in normotensive and hypertensive hemodialysis patients
Krassimir Katzarski,Jonas Nisell,Ivar Randmaa,Anders Danielsson,U. Freyschuss,Jonas Bergström +5 more
TL;DR: It is confirmed that extracellular fluid overload plays an important role in the pathogenesis of dialysis-associated hypertension and IVCD measured at the end or shortly after HD may therefore be misleading in assessing dry weight.
Journal ArticleDOI
Interdialytic weight gain, compliance with dialysis regimen, and age are independent predictors of blood pressure in hemodialysis patients.
TL;DR: Greater interdialytic weight gain and noncompliance with dialysis regimen are independently associated with higher blood pressure, and advancing age is associated with lower blood pressure levels in patients undergoing chronic hemodialysis.