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The clinical evaluation of chemotherapeutic agents in cancer

D. A. Karnofsky
- pp 191-205
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The article was published on 1949-01-01 and is currently open access. It has received 3213 citations till now. The article focuses on the topics: Cancer.

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A Randomized Trial of Surgery in the Treatment of Single Metastases to the Brain

TL;DR: It is concluded that patients with cancer and a single metastasis to the brain who receive treatment with surgical resection plus radiotherapy live longer, have fewer recurrences of cancer in the brain, and have a better quality of life than similar patients treated with radiotherapy alone.
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Measurement of health state utilities for economic appraisal.

TL;DR: A framework for economic appraisal is presented displaying the various components that must be measured, and showing how the three forms of analysis relate to the framework and to each other.

NCCN Clinical Practice Guidelines in Oncology (NCCN Guidelines

TL;DR: Lymphedema is a common complication after treatment for breast cancer and factors associated with increased risk of lymphedEMA include extent of axillary surgery, axillary radiation, infection, and patient obesity.
Journal ArticleDOI

Translation, Validation, and Norming of the Dutch Language Version of the SF-36 Health Survey in Community and Chronic Disease Populations

TL;DR: In this paper, the authors translate, validate, and generate normative data on the SF-36 Health Survey for use among Dutch- speaking residents of the Netherlands, followed the stepwise, iterative procedures developed by the IQOLA Project.
Journal ArticleDOI

Generic and disease-specific measures in assessing health status and quality of life.

TL;DR: Comparison studies are needed of the validity, reliability, and responsiveness of generic and disease-specific measures in the same population and in minority and age-specific groups.
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