Journal ArticleDOI
The Comparative Effectiveness of Sleeve Gastrectomy, Gastric Bypass, and Adjustable Gastric Banding Procedures for the Treatment of Morbid Obesity
Arthur M. Carlin,Telal M. Zeni,Wayne J. English,Abdelkader A. Hawasli,Jeffrey A. Genaw,Kevin R. Krause,Jon L. Schram,Kerry L. Kole,Jonathan F. Finks,John D. Birkmeyer,David Share,Nancy J. O. Birkmeyer +11 more
TLDR
With better weight loss than LAGB and lower complication rates than RYGB, SG is a reasonable choice for the treatment of morbid obesity and should be covered by both public and private payers.Abstract:
Objective:To evaluate the comparative effectiveness of sleeve gastrectomy (SG), laparoscopic gastric bypass (RYGB), and laparoscopic adjustable gastric banding (LAGB) procedures.Background:Citing limitations of published studies, payers have been reluctant to provide routine coverage for SG for theread more
Citations
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Journal ArticleDOI
Benefits and Risks of Bariatric Surgery in Adults: A Review.
TL;DR: All patients with severe obesity-and especially those with type 2 diabetes-should be engaged in a shared decision-making conversation about the risks and benefits of surgery compared with continuing usual medical and lifestyle treatment, and the decision about surgery should be driven primarily by informed patient preferences.
Journal ArticleDOI
Bariatric Surgery and Long-term Durability of Weight Loss
Matthew L. Maciejewski,Matthew L. Maciejewski,David Arterburn,David Arterburn,Lynn Van Scoyoc,Valerie Smith,Valerie Smith,William S. Yancy,William S. Yancy,Hollis J. Weidenbacher,Edward H. Livingston,Maren K. Olsen,Maren K. Olsen +12 more
TL;DR: These results provide further evidence of the beneficial association between surgery and long-term weight loss that has been demonstrated in shorter-term studies of younger, predominantly female populations.
Journal ArticleDOI
Resolvins, Specialized Proresolving Lipid Mediators, and Their Potential Roles in Metabolic Diseases
TL;DR: Evidence is reviewed that the failure of resolution programs contributes to metabolic diseases and that SPMs may play pivotal roles in their resolution, and specialized proresolving lipid mediators (SPMs) are novel autacoids that resolve inflammation, protect organs, and stimulate tissue regeneration.
Journal ArticleDOI
Mechanisms underlying weight loss after bariatric surgery
TL;DR: These mechanisms as well as their mediators are explored in the hope that their in-depth investigation will enable the optimization and individualization of surgical techniques, the development of equally effective but safer nonsurgical weight-loss interventions, and even the understanding of the pathophysiology of obesity itself.
Journal ArticleDOI
Long-term Outcomes of Bariatric Surgery: A National Institutes of Health Symposium
Anita P. Courcoulas,Susan Z. Yanovski,Denise E. Bonds,Thomas L. Eggerman,Mary Horlick,Myrlene A. Staten,David Arterburn +6 more
TL;DR: High-quality evidence shows that bariatric surgical procedures result in greater weight loss than nonsurgical treatments and are more effective at inducing initial type 2 diabetes mellitus remission in obese patients.
References
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Journal ArticleDOI
Bariatric surgery: a systematic review and meta-analysis.
Henry Buchwald,Yoav Avidor,Eugene Braunwald,Michael D. Jensen,Walter J. Pories,Kyle Fahrbach,Karen Schoelles +6 more
TL;DR: Effective weight loss was achieved in morbidly obese patients after undergoing bariatric surgery, and a substantial majority of patients with diabetes, hyperlipidemia, hypertension, and obstructive sleep apnea experienced complete resolution or improvement.
Journal ArticleDOI
Who would have thought it? An operation proves to be the most effective therapy for adult-onset diabetes mellitus.
Walter J. Pories,Melvin Swanson,Kenneth G. MacDonald,Stuart B. Long,Patricia G. Morris,Brenda M. Brown,Hisham A. Barakat,Richard A. deRamon,Jeanette M. Dolezal,G. Lynis Dohm +9 more
TL;DR: The gastric bypass operation provides long-term control of non-insulin-dependent diabetes mellitus (NIDDM) and antidiabetic effects appear to be due primarily to a reduction in caloric intake, suggesting that insulin resistance is a secondary protective effect rather than the initial lesion.
Journal ArticleDOI
Bariatric surgery. A systematic review and meta-analysis
TL;DR: Effective weight loss was achieved in morbidly obese patients after undergoing bariatric surgery, and a substantial majority of patients with diabetes, hyperlipidemia, hypertension, and obstructive sleep apnea experienced complete resolution or improvement.
Journal ArticleDOI
Bariatric Surgery versus Intensive Medical Therapy in Obese Patients with Diabetes
Philip R. Schauer,Sangeeta R. Kashyap,Kathy Wolski,Stacy A. Brethauer,John P. Kirwan,Claire E. Pothier,Susan Thomas,Beth Abood,Steven E. Nissen,Deepak L. Bhatt,Deepak L. Bhatt +10 more
TL;DR: In obese patients with uncontrolled type 2 diabetes, 12 months of medical therapy plus bariatric surgery achieved glycemic control in significantly more patients than medical therapy alone.
Journal ArticleDOI
Effect of laparoscopic Roux-en Y gastric bypass on type 2 diabetes mellitus.
Philip R. Schauer,Bartolome Burguera,Sayeed Ikramuddin,Dan Cottam,William Gourash,Giselle G. Hamad,George M. Eid,Samer G. Mattar,Ramesh K. Ramanathan,Emma Barinas-Mitchel,R. Harsha Rao,Lewis H. Kuller,David E. Kelley +12 more
TL;DR: Patients with the shortest duration, the mildest form of T2DM, and the greatest weight loss after surgery were most likely to achieve complete resolution of type 2 diabetes mellitus, suggesting that early surgical intervention is warranted to increase the likelihood of rendering patients euglycemic.