Myrlene A. Staten

TL;DR: The overall risk of death and other adverse outcomes after bariatric surgery was low and varied considerably according to patient characteristics, andExtreme values of body-mass index were significantly associated with an increased risk of the composite end point, whereas age, sex, race, ethnic group, and other coexisting conditions were not.

TL;DR: Among persons at high risk for type 2 diabetes not selected for vitamin D insufficiency, vitamin D3 supplementation at a dose of 4000 IU per day did not result in a significantly lower risk of diabetes than placebo.

TL;DR: High-quality evidence shows that bariatric surgical procedures result in greater weight loss than nonsurgical treatments and are more effective at inducing initial type 2 diabetes mellitus remission in obese patients.

TL;DR: The strong relation of leptin with obesity is consistent with leptin production being proportional to mass of adipose tissue, but the independent association with insulin concentration suggests a possible role in insulin resistance or hyperinsulinaemia.

TL;DR: This pragmatic, unmasked clinical trial aims to compare commonly used diabetes medications, when combined with metformin, on glycemia-lowering effectiveness and patient-centered outcomes and provide guidance to clinicians about the most appropriate medications to treat T2DM.