The correlation of promotion of tumour growth and of induction of hyperplasia in epidermal two-stage carcinogenesis.
J V Frei,P Stephens +1 more
TLDR
The correlation of promotion of tumour growth and of induction of hyperplasia in epidermal two-stage carcinogenesis is studied.Abstract:
The correlation of promotion of tumour growth and of induction of hyperplasia in epidermal two-stage carcinogenesisread more
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Book ChapterDOI
Tumor promoters and the mechanism of tumor promotion.
TL;DR: This chapter reviews the studies on the mechanism of tumor promotion in mouse skin by croton oil and phorbol diesters and on the effects of these compounds on cell cultures of various types and discusses the findings in the field of tumor promoters during mid- 1979.
Journal Article
Studies on the mechanism of skin tumor promotion.
Henry Hennings,R. K. Boutwell +1 more
TL;DR: At a level which was effective as a skin tumor promoter, croton oil increased the rate of incorporation of tritiated precursors into mouse skin macromolecules and stimulation of RNA synthesis may be important in the process of promotion.
Journal ArticleDOI
Toxicity of silver ions, metallic silver, and silver nanoparticle materials after in vivo dermal and mucosal surface exposure: A review
TL;DR: Silver may cause genotoxicity, but additional data are required to assess its carcinogenic potential and other reported toxicities include hepatic, renal, neurological, and hematological effects.
Book ChapterDOI
Sequential Aspects of Chemical Carcinogenesis: Skin
TL;DR: In the rabbit experiments referred to above, it was possible to show that papillomas that had apparently regressed completely could be made to reappear at the identical sites by means of nonspecific stimuli, which led Rous and his associates to conclude that foci of tumor cells remained in a "latent" or dormant state, capable of being "reawakened," and that the induction process on the one hand and the