Journal ArticleDOI
The effect of relaxin and prostaglandin E2 on the motility of human spermatozoa
Jose M. Colon,Jose M. Colon,Frances Ginsburg,Frances Ginsburg,Joseph B. Lessing,Joseph B. Lessing,Cy Schoenfeld,Cy Schoenfeld,Laura T. Goldsmith,Laura T. Goldsmith,Richard D. Amelar,Richard D. Amelar,Lawrence Dubin,Lawrence Dubin,Gerson Weiss,Gerson Weiss +15 more
TLDR
In this article, the effects of porcine relaxin and prostaglandin E2 on the motility of human spermatozoa were examined and a dose-response study revealed that PGE2 at a concentration of 25 micrograms/ml is most effective in improving the motile of washed human sperm.About:
This article is published in Fertility and Sterility.The article was published on 1986-12-01. It has received 46 citations till now. The article focuses on the topics: Sperm motility & Relaxin.read more
Citations
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Journal ArticleDOI
Docosahexaenoic acid supplementation fully restores fertility and spermatogenesis in male delta-6 desaturase-null mice
Manuel Roqueta-Rivera,Chad K. Stroud,Wanda M. Haschek,Sandeep J. Akare,Mariangela Segre,Richard S. Brush,Martin-Paul Agbaga,Robert E. Anderson,Rex A. Hess,Manabu T. Nakamura +9 more
TL;DR: DHA was capable of restoring all observed impairment in male reproduction, whereas 22:4n6 formed from dietary AA may act as an inferior substitute for DHA.
Book ChapterDOI
Physiology and Molecular Biology of the Relaxin Peptide Family
TL;DR: It is now accepted that relaxin is a member of a family of peptide hormones that includes seven members in humans—three relaxin peptides (H1, H2, and H3) and insulin-like peptides(INSL) 3, 4, 5, and 6; all these genes evolved from an ancestral relaxin-3 gene in (lower) vertebrates.
Journal ArticleDOI
Hyaluronic acid (Sperm Select) improves retention of sperm motility and velocity in normospermic and oligospermic specimens.
TL;DR: Sperm Select improves the retention of sperm motility (most prominently velocity) apparently due to a direct action of hyaluronic acid on sperm metabolism or contractility rather than to preservation of sperm membrane integrity.
Journal ArticleDOI
Comparison of motility stimulants for cryopreserved human semen
Diane G. Hammitt,Erik Bedia,Penni R. Rogers,Craig H. Syrop,James F. Donovan,Roger A. Williamson +5 more
TL;DR: Results indicate that, of the chemicals examined, pentoxifylline is superior for motility stimulation of cryopreserved sperm.
Journal ArticleDOI
The Application of Pentoxifylline in the Stimulation of Sperm Motion in Men Undergoing Electroejaculation
TL;DR: These studies show that pentoxifylline stimulation can improve the movement characteristics of asthenospermic sperm from neurologically impaired men and may improve the chances for conception in some cases of male-factor infertility.
References
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Journal ArticleDOI
Cyclic adenosine 3',5' monophosphate, calcium and protein phosphorylation in flagellar motility.
Joseph S. Tash,Anthony R. Means +1 more
TL;DR: The identification of cAMP-dependent protein kinase, calmodulin and myosin light chain kinase in the sperm head suggests that cAMP and calcium-dependent phosphorylations are also involved in the control of the fertilization process, i.e., the acrosome reaction, in a manner similar to that known for theControl of stimulus/secretion coupling.
Journal ArticleDOI
Prostaglandins, cyclic nucleotides and cell function
TL;DR: The recent isolation of a receptor unique to PGF 2α and the demonstrated ability of this prostaglandin to increase tissue cyclic GMP levels are consistent with this concept that the E-prostaglandins and P GF 2α play distinctly different roles in cell regulation.
Journal ArticleDOI
Radioimmunoassay (RIA) of relaxin in sera of various species using an antiserum to porcine relaxin.
TL;DR: The cross-reactivity between antiporcine relaxin antibody and the relaxinlike substances in the blood of other mammals during pregnancy was sufficiently high to permit the assay of 0.1–0.5 ml of serum or plasma samples.
Journal ArticleDOI
Effect of aspirin on human seminal prostaglandins.
J.G. Collier,R.J. Flower +1 more
TL;DR: The prostaglandin E and F content of human semen was reduced in subjects taking aspirin for one week in order to reduce the risk of meningitis.
Journal ArticleDOI
Analysis of the direct effects of prostaglandins on human sperm function.
R. J. Aitken,R. W. Kelly +1 more
TL;DR: It is concluded that certain prostaglandins may have a direct action on the functional competence of human spermatozoa.