Journal ArticleDOI
The expedient synthesis of 1,5-benzothiazepines as a family of cytotoxic drugs.
Kapil Arya,Anshu Dandia +1 more
TLDR
The expedient synthesis of 1,5-benzothiazepines using LaY zeolite under stirring condition is reported and synthesized compound screened for cytotoxic activity provides a simple and green synthetic methodology under environmentally friendly conditions.About:
This article is published in Bioorganic & Medicinal Chemistry Letters.The article was published on 2008-01-01. It has received 45 citations till now.read more
Citations
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Journal ArticleDOI
Step-economic, efficient, ZnS nanoparticle-catalyzed synthesis of spirooxindole derivatives in aqueous medium viaKnoevenagel condensation followed by Michael addition
TL;DR: An environmentally friendly, one-pot, three-component ZnS nanoparticle-mediated synthesis of biologically important spirooxindole derivatives in water under ultrasonic irradiation is described in this article.
Journal ArticleDOI
Versatile three component procedure for combinatorial synthesis of biologically relevant scaffold spiro[indole-thiazolidinones] under aqueous conditions
TL;DR: The present method is more convenient and efficient as compared to multistep conventional processes and it obviates the azeotropical removal of water and use of carcinogenic solvents and dehydrating agents.
Journal ArticleDOI
Zeolite supported Brønsted-acid ionic liquids: an eco approach for synthesis of spiro[indole-pyrido[3,2-e]thiazine] in water under ultrasonication
TL;DR: In this article, a zeolite supported Bronsted-acid catalyst system was developed using different Bronsted acid ionic liquids supported on ZSM-5 Zeolite, and catalytic activity was tested via aqueous-mediated ultrasound-promoted synthesis of novel N-substituted spiro heterocycles.
Book ChapterDOI
Palladium-Copper Catalyzed Alkyne Activation as an Entry to Multicomponent Syntheses of Heterocycles
TL;DR: In this paper, the coupling-isomerization reaction (CIR) was used for the synthesis of 3-halo furans, pyrroles, pyrazoles and annelated pyridines.
Journal ArticleDOI
Direct construction of novel dispiro heterocycles through 1,3-dipolar cycloaddition of azomethine ylides
TL;DR: In this article, the 1,3-dipolar cycloaddition of 2-oxo-(2H)-acenaphthylen-1-ylidene-malononitrile and 2-fluoren-9-ylide-morphosine was investigated for the first time with azomethine ylides generated in situ from N-substituted isatin and sarcosine to furnish novel dispiro heterocycles.
References
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Journal ArticleDOI
Inorganic Solid Acids and Their Use in Acid-Catalyzed Hydrocarbon Reactions
TL;DR: In this article, the authors tried to describe perhaps the most important solid acids based on inorganic oxides, going from their preparation procedures and characterization, to their catalytic activity for a series of hydrocarbon reactions.
Journal ArticleDOI
Features of apoptotic cells measured by flow cytometry
Zbigniew Darzynkiewicz,S. Bruno,G. Del Bino,Wojciech Gorczyca,Michel A. Hotz,P. Lassota,Frank Traganos +6 more
TL;DR: The present review describes several methods to characterize and differentiate between two different mechanisms of cell death, apoptosis and necrosis, applied to studies of apoptosis triggered in the human leukemic HL-60 cell line by DNA topoisomerase I or II inhibitors, and in rat thymocytes by either topoisomersase inhibitors or prednisolone.
Book
An Introduction to Zeolite Molecular Sieves
TL;DR: In this paper, the structure of Zeolite topology is classified by SBU Content Specific Zeolites Topologies ZEOLITE STRUCTURE IDENTIFICATION and CHARACTERIZATION: X-Ray Methods Spectroscopic Techniques Resonance Spectroscopy ZEolite SYNTHES: Reaction Variables in ZEO Synthesis Kinetics and Mechanism in ZeOolite Crystallizations, Ion Exchange Equilibria Ion Exchange Kinetics, Gaseous Diffusion in ZOI and DRYING AGENTS.