The fate of Brugia pahangi larvae immediately after feeding by infective vector mosquitoes

TLDR: A relatively heavy (20 larvae) infection from a single mosquito was observed in one instance; however, in approximately one half of the mice exposed to mosquitoes harbouring infective larvae, no larvae were transmitted to the tissues of the mouse.

Abstract: A method is described whereby the fate of infective filarial larvae after feeding by vector mosquitoes may be estimated. In this investigation, Aedes togoi with a 77% rate of infection and an average of 7·5 infective Brugia pahangi larvae per mosquito, were permitted to feed on mice. The following observations were made: 1. 1. 22·3% of the expected number of infective larvae were transmitted to the tissues of mice. 2. 2. 32·3% of larvae remained in the mosquito. 3. 3. 45·4% of larvae were estimated to have been lost on the surface of the skin. 4. 4. A relatively heavy (20 larvae) infection from a single mosquito was observed in one instance; however, in approximately one half of the mice exposed to mosquitoes harbouring infective larvae, no larvae were transmitted to the tissues of the mice.