Journal ArticleDOI
The guttiferones, HIV-inhibitory benzophenones from Symphonia globulifera, Garcinia livingstonei, Garcinia ovalifolia and Clusia rosea
Kirk R. Gustafson,John W. Blunt,Murray H. G. Munro,Richard W. Fuller,Tawnya C. McKee,John H. Cardellina,James B. McMahon,Gordon M. Cragg,Michael R. Boyd +8 more
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TLDR
In this article, a series of new polyisoprenylated benzophenone derivatives named guttiferones A-E (1, 2, 3, 4, 5) were found to inhibit the cytophatic effects of in vitro HIV infection.About:
This article is published in Tetrahedron.The article was published on 1992-01-01. It has received 271 citations till now. The article focuses on the topics: Garcinia livingstonei & Symphonia globulifera.read more
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Polycyclic Polyprenylated Acylphloroglucinols
Journal ArticleDOI
Bioactive constituents of brazilian red propolis.
Boryana Trusheva,Milena Popova,Vassya Bankova,Svetlana Simova,Maria Cristina Marcucci,Patricia Laguna Miorin,Flavia da Rocha Pasin,Iva Tsvetkova +7 more
TL;DR: In a new propolis type, red Brazilian propolis, 14 compounds were identified, among them simple phenolics, triterepenoids, isoflavonoids, prenylated benzophenones and a naphthoquinone epoxide (isolated for the first time from a natural source).
Journal ArticleDOI
Research Progress of Polycyclic Polyprenylated Acylphloroglucinols.
TL;DR: The progress of research into the chemistry and biological activity of 421 natural PPAPs in the past 11 years as well as in-depth studies of biological activities and total synthesis of somePPAPs isolated before 2006 are discussed.
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Molecular Systematic Analysis Reveals Cryptic Tertiary Diversification of a Widespread Tropical Rain Forest Tree
TL;DR: This study establishes three marine dispersal events leading to the colonization of Mesoamerica, the Amazon basin, and the West Indies, thus supporting the paleontological data and providing a historical biogeographic hypothesis to account for differences in the patterns of β diversity within MesOamerican and Amazonian forests.
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Antiviral and antimicrobial activities of Colombian medicinal plants
TL;DR: It is concluded that these Colombian medicinal plants represent an untapped source of potentially useful antivirals and are worthy of further study.
References
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Journal ArticleDOI
New Soluble-Formazan Assay for HIV-1 Cytopathic Effects: Application to High-Flux Screening of Synthetic and Natural Products for AIDS-Antiviral Activity
Owen S. Weislow,Rebecca Kiser,Donald L. Fine,John P. Bader,Robert H. Shoemaker,Michael R. Boyd +5 more
TL;DR: In this paper, an effective and optimally safe microculture method for rapid and convenient assay of the in vitro cytopathic effects of human immunodeficiency virus (HIV-1) on human lymphoblastoid or other suitable host cells.
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Xanthones from guttiferae
Graham J. Bennett,Hiok-Huang Lee +1 more
TL;DR: In this article, the distribution of xanthones is examined in relation to the taxonomic divisions of the Guttiferae, and various pharmacological properties of Xanthones are summarized.
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A semiautomated multiparameter approach for anti-HIV drug screening.
TL;DR: A series of complementary assays for initial follow-up confirmation and prioritization of new active anti-HIV compounds identified by the U.S. National Cancer Institute's large-scale in vitro primary anti-hIV screen yields a maximum amount of antiviral and cytotoxicity information from a minimum amount of sample.
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Kolanone, a novel polyisoprenylated benzophenone with antimicrobial properties from the fruit of Garcinia kola.
TL;DR: A tentative structure for kolanone has been proposed based on a comparison of its spectral data with that published for other compounds of this class.
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On the structures of garcinol, isogarcinol and camboginol
TL;DR: A new polyisoprenylated phenolic pigment, garcinol, and its colourless isogarcinol, have been isolated from Garcinia indica and their structures proposed on the basis of chemical and spectral data.