Journal ArticleDOI
The impact of tumor morcellation during surgery on the prognosis of patients with apparently early uterine leiomyosarcoma
Jeong-Yeol Park,Sun-Kyung Park,Dae Yeon Kim,Jong-Hyeok Kim,Yong-Man Kim,Young-Tak Kim,Joo-Hyun Nam +6 more
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TLDR
Tumor morcellation during surgery increased the rate of abdomino-pelvic dissemination and adversely affected DFS and OS in patients with apparently early uterine LMS.About:
This article is published in Gynecologic Oncology.The article was published on 2011-08-01. It has received 298 citations till now. The article focuses on the topics: Hysterectomy & Uterine sarcoma.read more
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UK guidelines for the management of soft tissue sarcomas.
TL;DR: These guidelines are an update of the previous version published in 2010 and were intended to provide a framework for the multidisciplinary care of patients with soft tissue sarcomas, and have been updated and amended with reference to other European and US guidance.
Journal ArticleDOI
Peritoneal dissemination complicating morcellation of uterine mesenchymal neoplasms.
Michael A. Seidman,Titilope Oduyebo,Michael G. Muto,Christopher P. Crum,Marisa R. Nucci,Bradley J. Quade +5 more
TL;DR: Data suggest uterine morcellation carries a risk of disseminating unexpected malignancy with apparent associated increase in mortality much higher than appreciated currently.
Journal ArticleDOI
Retrospective cohort study evaluating the impact of intraperitoneal morcellation on outcomes of localized uterine leiomyosarcoma.
Suzanne George,Constance M. Barysauskas,César Serrano,Titilope Oduyebo,Jose Alejandro Rauh-Hain,Marcela G. del Carmen,George D. Demetri,Michael G. Muto +7 more
TL;DR: The impact of intraperitoneal morcellation on the outcomes of patients with ULMS was assessed to assess the impact of minimally invasive approaches for the management of leiomyomas.
Journal ArticleDOI
Impact of morcellation on survival outcomes of patients with unexpected uterine leiomyosarcoma: A systematic review and meta-analysis
TL;DR: The data support a significant correlation between uterine morcellation and an increased risk of intra-abdominal recurrence in patients affected by unexpected ULMS, however, the limited data on this issue and the absence of high level of evidence suggest the need of further studies designed to estimate the risk to benefit ratio.
Journal ArticleDOI
Clinical application of diffusion-weighted imaging for preoperative differentiation between uterine leiomyoma and leiomyosarcoma
TL;DR: In this paper, the clinical usefulness of diffusion-weighted imaging (DWI) and the apparent diffusion coefficient (ADC) value for preoperative differentiation between uterine leiomyoma and myoma was investigated.
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Management of uterine malignancy found incidentally after supracervical hysterectomy or uterine morcellation for presumed benign disease.
Mark H. Einstein,Richard R. Barakat,Dennis S. Chi,Yukio Sonoda,K.M. Alektiar,Martee L. Hensley,Nadeem R. Abu-Rustum +6 more
TL;DR: A retrospective case series of patients referred to the authors' institution with uterine malignancy who previously underwent supracervical hysterectomy or uterine morcellation at the time of original surgery for presumed benign uterine disease found that patients who undergo completion surgery with restaging and are not upstaged appear to have a good prognosis.
Journal Article
Treatment of uterine leiomyosarcoma.
Andrew Berchuck,Stephen C. Rubin,William J. Hoskins,Patricia E. Saigo,Virginia K. Pierce,John L. Lewis +5 more
TL;DR: The disease-free survival rate for all patients in this study was 22%; those patients who presented with stage I and II disease had a 29% survival rate, and no objective responses to radiation therapy were seen in these patients.
Journal Article
Management of retroperitoneal sarcomas.
TL;DR: Survival was significantly better for patients who had complete surgical excision of their tumors, and the therapeutic challenges in the treatment of retroperitoneal sarcomas continue to be the development of therapy that will increase the rates of complete resection, decrease the rate of local recurrence, and enhance patient survival.
Journal ArticleDOI
Uterine leiomyosarcoma: does the primary surgical procedure matter?
TL;DR: In patients with stage I LMS, primary surgery involving tumor injury seems to be associated with a worse prognosis than total hysterectomy as a primary intervention.
Journal ArticleDOI
Preoperative Diagnosis and Treatment Results in 106 Patients with Uterine Sarcoma in Hokkaido, Japan
Satoru Sagae,Kohki Yamashita,Shinichi Ishioka,Yoshihiro Nishioka,Katsuhiko Terasawa,Mitsuru Mori,Katsushige Yamashiro,Toshitaka Kanemoto,Ryuichi Kudo +8 more
TL;DR: Accurate preoperative diagnosis of uterine sarcoma was difficult, and no residual disease at surgery was the most important prognostic factor in patients with this disease; postoperative adjuvant therapy had little effect on survival, especially in early-stage disease.