Journal ArticleDOI
The uterine epithelium of Ascaris lumbricoides as a model system for the study of polyploidy
A.D. Floyd,F.J. Swartz +1 more
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Use of Ascaris uterine epithelium as an experimental system may yield important information concerning the significance of polyploidy in biological systems.About:
This article is published in Experimental Cell Research.The article was published on 1969-08-01. It has received 16 citations till now. The article focuses on the topics: Epithelium.read more
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Relationship of hepatocyte ploidy levels with body size and growth rate in mammals.
TL;DR: A high negative correlation between the hepatocyte ploidy level and the metabolic scope indicates a low safety margin of organs with a high number of polyploid cells, challenging a common opinion that increasing ploids enhances the functional capability of cells or is necessary for cell differentiation.
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A Cytophotometric analysis of the DNA in the nucleus of the giant cell, R-2, in Aplysia
TL;DR: The cytophotometrically measured DNA in the nucleus of R-2, the giant neuron of the abdominal ganglion in Aplysia, suggests that this is the most highly polyploid nucleus yet described.
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A live-born infant with 69 chromosomes
Roy D. Schmickel,Eugene M. Silverman,Alton D. Floyd,Francis E. Payne,Janet M. Pooley,Malcolm L. Beck +5 more
TL;DR: This study of a live-born infant with 69 chromosomes reveals that there is a clinicallyrecognizable syndrome caused by triploidy in the human, and phenotypic expression at the cellular level indicates that the cellular growth pattern is normal, although the cells are larger than their diploid counterparts.
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Satellite DNA properties of the germ line limited DNA and the organization of the somatic genomes in the nematodes Ascaris suum and Parascaris equorum.
TL;DR: Comparison of the reassociation kinetics of germ line and soma DNA demonstrates for both species that the eliminated DNA sequences are highly repetitive, and the DNA sequence arrangement ofAscaris does not follow the short period interspersion pattern observed in most organism.
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An integrating microdensitometer for biological cells
TL;DR: In this article, a photoelectric method for the rapid determination of the total absorption of biological cells is described, where the image of the cell, formed by a microscope, is scanned by a mechanically-driven aperture behind which is mounted a photomultiplier.
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Metabolic controls in cultured mammalian cells.
TL;DR: The more complete exploration of homotypic and heterotypic cellular interactions, the spontaneous transformations sometimes observed in cultured cells, the mode of action of cytotoxic agents, and the multiple metabolic effects of viral infection can be expected to throw light on the basic mechanisms underlying such complex processes as differentiation, senescence, and cancer.