Open AccessJournal Article
Total enteral nutrition in prevention of pancreatic necrotic infection in severe acute pancreatitis
TLDR
Total enteral nutrition is better than total parenteral nutrition in prevention of pancreatic necrotic infection in severe acute pancreatitis.Abstract:
【Objectives】 This study was designed to evaluate the effects of total enteral nutrition and total parenteral nutrition in prevention of pancreatic necrotic infection in severe acute pancreatitis.【Methods】 107 patients were enrolled in ICU between November 2003 and December 2007.In the first week of hospitalization,54 patients received total parenteral nutrition,and 53 received total enteral nutrition.All patients were concomitantly administered with sufficient prophylactic antibiotics.CT scan and C-reaction proteins indicated a similar clinical severity in both groups.【Results】 80% subjects developed organ failure in the group with total parenteral nutrition,which was significantly higher than that in the group with total enteral nutrition(21.00%);80.00% patients in total parenteral nutrition and 22.00%(P 0.05) in total enteral nutrition underwent the surgical intervention.The incidence of pancreatic septic necroses in the group with total enteral nutrition(23.00%) was significantly lower than that in the group with total parenteral nutrition(72.00%)(P 0.05).The mortality of patients(43.00%) on total parenteral nutrition was significantly increased as compared to 11.00%(P 0.05) in the group received total enteral nutrition.【Conclusion】 Total enteral nutrition is better than total parenteral nutrition in prevention of pancreatic necrotic infection in severe acute pancreatitis.read more
Citations
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Meta-analysis: total parenteral nutrition versus total enteral nutrition in predicted severe acute pancreatitis.
TL;DR: Total enteral nutritional support is associated with lower mortality, fewer infectious complications, decreased organ failure and surgical intervention rate compared to parenteral nutritional support.
Journal ArticleDOI
Effect of enteral nutrition and ecoimmunonutrition on bacterial translocation and cytokine production in patients with severe acute pancreatitis.
TL;DR: EN plays effective roles in the treatment of SAP by decreasing the expression of endotoxin, TNF-α, and IL-6 and the bacterial translocation, enhancing the expressionOf IL-10, and the combination of EIN with EN results in more therapeutic benefits than EN alone.
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Early management of acute pancreatitis: A review of the best evidence
TL;DR: In the 20th century, early management of acute pancreatitis often included surgical intervention, despite overwhelming mortality as discussed by the authors, and the emergence of high-quality evidence (randomized controlled trials and meta-analyses) over the past two decades has notably shifted the treatment paradigm towards predominantly non-surgical management early in the course of acute pneumonia.
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Nutrition in acute pancreatitis: a critical review
Piet J. Lodewijkx,Marc G. Besselink,Ben J.M. Witteman,Nicolien J. Schepers,Hein G. Gooszen,Hjalmar C. van Santvoort,Olaf J. Bakker +6 more
TL;DR: This review provides a critical review of the available literature and concludes that enteral nutrition is superior to parenteral nutrition, although several limitations should be taken into account.
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Early nasojejunal tube feeding versus nil-by-mouth in acute pancreatitis: A randomized clinical trial.
Davor Štimac,Goran Poropat,Goran Hauser,Vanja Licul,Neven Franjić,P. Valkovic Zujic,Sandra Milić +6 more
TL;DR: Results showed no significant reduction of persistent organ failure and mortality in patients with AP receiving early EN compared to patients treated with no nutritional support (NCT01965873).
References
More filters
Journal ArticleDOI
Meta-analysis: total parenteral nutrition versus total enteral nutrition in predicted severe acute pancreatitis.
TL;DR: Total enteral nutritional support is associated with lower mortality, fewer infectious complications, decreased organ failure and surgical intervention rate compared to parenteral nutritional support.
Journal ArticleDOI
Effect of enteral nutrition and ecoimmunonutrition on bacterial translocation and cytokine production in patients with severe acute pancreatitis.
TL;DR: EN plays effective roles in the treatment of SAP by decreasing the expression of endotoxin, TNF-α, and IL-6 and the bacterial translocation, enhancing the expressionOf IL-10, and the combination of EIN with EN results in more therapeutic benefits than EN alone.
Journal ArticleDOI
Early management of acute pancreatitis: A review of the best evidence
TL;DR: In the 20th century, early management of acute pancreatitis often included surgical intervention, despite overwhelming mortality as discussed by the authors, and the emergence of high-quality evidence (randomized controlled trials and meta-analyses) over the past two decades has notably shifted the treatment paradigm towards predominantly non-surgical management early in the course of acute pneumonia.
Journal ArticleDOI
Nutrition in acute pancreatitis: a critical review
Piet J. Lodewijkx,Marc G. Besselink,Ben J.M. Witteman,Nicolien J. Schepers,Hein G. Gooszen,Hjalmar C. van Santvoort,Olaf J. Bakker +6 more
TL;DR: This review provides a critical review of the available literature and concludes that enteral nutrition is superior to parenteral nutrition, although several limitations should be taken into account.
Journal ArticleDOI
Early nasojejunal tube feeding versus nil-by-mouth in acute pancreatitis: A randomized clinical trial.
Davor Štimac,Goran Poropat,Goran Hauser,Vanja Licul,Neven Franjić,P. Valkovic Zujic,Sandra Milić +6 more
TL;DR: Results showed no significant reduction of persistent organ failure and mortality in patients with AP receiving early EN compared to patients treated with no nutritional support (NCT01965873).