Journal ArticleDOI
Total Synthesis of (-)-Grayanotoxin III
Toshiyuki Kan,Seijiro Hosokawa,Shinji Nara,Masato Oikawa,Shinya Ito,Fuyuhiko Matsuda,Haruhisa Shirahama +6 more
TLDR
The total synthesis of (-)-grayanotoxin III (3), a unique tetracyclic diterpene isolated from the leaves of various plants of the family Ericaceae, has been successfully accomplished featuring the highly stereoselective cyclization reactions induced by SmI 2.Abstract:
Total synthesis of (-)-grayanotoxin III (3), a unique tetracyclic diterpene isolated from the leaves of various plants of the family Ericaceae, has been successfully accomplished featuring the highly stereoselective cyclization reactions induced by SmI 2read more
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Journal ArticleDOI
Sequencing Reactions with Samarium(II) Iodide.
Journal ArticleDOI
Thiyl Radicals in Organic Synthesis
TL;DR: The thiol−olefin cooxidation process was applied to the total synthesis of antimalarial agent yingzhaosu A and was extended to include the more challenging 1,5-dienes, from which six-membered ring endoperoxides can be obtained.
Journal ArticleDOI
Samarium(II)-iodide-mediated cyclizations in natural product synthesis.
TL;DR: A review, cyclization reactions in natural product synthesis of 4-9 membered and larger rings were discussed.
Journal ArticleDOI
Reagent-Controlled Transition-Metal-Catalyzed Radical Reactions
Andreas Gansäuer,Harald Bluhm +1 more
TL;DR: Chain reactions constituted an important breakthrough in the application of radical chemistry in organic synthesis, and the use of chain reactions has resulted in a number of very impressive total syntheses of natural products.
Journal ArticleDOI
Accessing the Synthetic Chemistry of Radical Ions
TL;DR: A brief review of radical ion chemistry can be found in this article, where the use of transition metal photocatalysis is used as a convenient means to investigate radical ion-mediated transformations.
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Grayanoids from the Ericaceae family: structures, biological activities and mechanism of action
Yong Li,Yun-Bao Liu,Shi-Shan Yu +2 more