Journal ArticleDOI
Transient hypoxæmia during sleep in chronic bronchitis and emphysema
Neil J. Douglas,Peter M. A. Calverley,R. J. E. Leggett,H.M. Brash,D. C. Flenley,V. Brezinova +5 more
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TLDR
It is suggested that these hypoxaemic episodes result from a combination of hypoventilation and impaired ventilation/ perfusion relationships and that these episodes may contribute to the development of the pulmonary hypertension and secondary polycythaemia which characterises "blue and bloated" patients.About:
This article is published in The Lancet.The article was published on 1979-01-06. It has received 247 citations till now. The article focuses on the topics: Chronic bronchitis & Hypoventilation.read more
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Chronic obstructive pulmonary disease
TL;DR: The most important bacterial causes of exacerbations of COPD are nontypeable Haemophilus influenzae, Moraxella catarrhalis, Streptococcus pneumoniae and Chlamydia pneumoniae.
Journal ArticleDOI
Nasal pressure support ventilation plus oxygen compared with oxygen therapy alone in hypercapnic COPD.
TL;DR: Nasal positive-pressure ventilation may be a useful addition to LTOT in stable hypercapnic COPD as compared with run-in and oxygen alone, and quality of life with oxygen plus NPSV was significantly better than with oxygen alone.
Journal ArticleDOI
Respiration during sleep in normal man.
TL;DR: Respiratory volumes and timing have been measured in 19 healthy adults during wakefulness and sleep, finding the greatest reduction occurring during REM sleep, when there is a parallel reduction in inspiratory drive.
Journal ArticleDOI
Snoring as a risk factor for hypertension and angina pectoris
TL;DR: The association of snoring with hypertension and ischaemic heart disease (IHD) was tested by postal questionnaire in a population of 3847 men and 3664 women aged 40-69 years and an association between angina pectoris and habitual snoring was observed.
Journal ArticleDOI
Neuropsychologic Findings in Hypoxemic Chronic Obstructive Pulmonary Disease
Igor Grant,Robert K. Heaton,A. John McSweeny,Kenneth M. Adams,Richard M. Timms,Richard M. Timms +5 more
TL;DR: It is concluded that cerebral disturbance is common in hypoxemic COPD and may be related in part to decreased availability of oxygen to the brain.
References
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Journal ArticleDOI
The sleep apnea syndromes.
Journal ArticleDOI
Pathogenesis of upper airway occlusion during sleep
TL;DR: Ten patients with daytime somnolence and obesity were found to have periodic airway occlusion (AO) during nocturnal sleep, and it is speculated that genioglossal force act,s to open the oropharynx and that negative pharyngeal pressure promotes pharynGEal closure.
Journal ArticleDOI
Observations on the Pulmonary Arterial Blood Pressure in the Cat
U. S. v. Euler,G. Liljestrand +1 more
TL;DR: The experiments seem to warrant the conclusion, that the regulation of the pulmonary blood flow is mainly mediated by a local action of the blood and alveolar gases leading to an adequate distribution of theBlood through the various parts of the lungs according to the effeciency of aeration.
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