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Open AccessJournal ArticleDOI

Transmural cellular passage in vascular sinuses of rat bone marrow.

Leon Weiss
- 01 Aug 1970 - 
- Vol. 36, Iss: 2, pp 189-208
TLDR
The structure of vascular sinuses in rat bone marrow is modified as cells cross their wall and two correlates of such infiltration are elevation of adventitial cells from the wall and the creation of advential spurs extending into perisinusal hematopoietic spaces.
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This article is published in Blood.The article was published on 1970-08-01 and is currently open access. It has received 108 citations till now. The article focuses on the topics: Bone marrow.

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Citations
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Journal ArticleDOI

Neutrophil kinetics in health and disease

TL;DR: Current understanding of how neutrophils are released from the bone marrow is outlined, in particular, the role of the CXC chemokine receptor 4/stromal-derived factor 1 axis and the relative size and role of freely circulating and marginated pools within the vascular compartment are outlined.
Journal ArticleDOI

Regulation of hemopoiesis by bone marrow stromal cells and their products

TL;DR: The ability to grow nonhemopoietic, connective tissue cells of marrow origin in vitro and the demonstration that these supported hemopoiesis upon transplantation to ectopic sites in vivo strengthened this premise.
Journal Article

A murine model of experimental metastasis to bone and bone marrow.

TL;DR: An animal model in which B16 melanoma cells injected in the left cardiac ventricle reproducibly colonize specific sites of the skeletal system of mice suggests that the injected tumor cells lodge, survive in the hematopoietic bone marrow environment, and grow to destroy adjacent bone.
Journal ArticleDOI

The kinetics of human granulopoiesis following treatment with granulocyte colony-stimulating factor in vivo

TL;DR: The dramatic neutrophil response to granulocyte colony-stimulating factor can be accommodated by a relatively modest increase in granulopoietic activity.
Journal ArticleDOI

The hematopoietic microenvironment of the bone marrow: An ultrastructural study of the stroma in rats

TL;DR: The stroma and vascular sinuses are described by scanning and transmission electron microscopy and in freeze‐fracture etch replicas in normal rat femoral marrow and in rats made eosinophilic by larvae of trichinella spiralis.
References
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Journal ArticleDOI

Staining of Tissue Sections for Electron Microscopy with Heavy Metals

TL;DR: Certain hitherto unobserved details are revealed and some sort of specificity exists, although the factors involved are not yet understood.
Book

A Textbook of Histology

TL;DR: The cell Epithelium Glands and secretion Blood Connective tissue proper Adipose tissue Cartilage Bone Bone marrow and blood cell formation Muscular tissue The nervous tissue, Jay B. Angevine
Journal ArticleDOI

Simple methods for "staining with lead" at high pH in electron microscopy.

TL;DR: It is thought that in these highly alkaline staining solutions lead is present as an hydroxide complex anion (plumbite ion) and that this anion is responsible for the staining, and the methods of preparation are based on this hypothesis.
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