Open AccessJournal Article
Treatment of gastric cancer
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This article is published in Revista de medicina de la Universidad de Navarra.The article was published on 1982-03-01 and is currently open access. It has received 263 citations till now. The article focuses on the topics: Cancer.read more
Citations
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Journal ArticleDOI
Gastric adenocarcinoma: review and considerations for future directions.
TL;DR: This update reviews the epidemiology and surgical management, and the controversies of gastric adenocarcinoma, and provides the relevance of outcome data to surgical decision-making and discusses the application of gene-expression analysis to clinical practice.
Journal ArticleDOI
Exosomal transfer of tumor-associated macrophage-derived miR-21 confers cisplatin resistance in gastric cancer cells
TL;DR: It is shown that M2 polarized macrophages promoted cisplatin (DDP) resistance in gastric cancer cells and exosomes derived from M2 macrophage (M2-exos) are involved in mediating the resistance to DDP.
Journal ArticleDOI
Exosomes derived from human mesenchymal stem cells confer drug resistance in gastric cancer
Runbi Ji,Bin Zhang,Xu Zhang,Jianguo Xue,Xiao Yuan,Yongmin Yan,Mei Wang,Wei Zhu,Hui Qian,Wenrong Xu +9 more
TL;DR: It is found that MSC-exosomes significantly induced the resistance of gastric cancer cells to 5-fluorouracil both in vivo and ex vivo, and Targeting the interaction between MSCs and cancer cells may help improve the efficacy of chemotherapy in Gastric cancer.
Journal ArticleDOI
PARP inhibitor combination therapy.
TL;DR: Both the pre-clinical and clinical evidence for the utility of such combinations are summarized and the future prospects and challenges for PARP inhibitor combinatorial therapies are discussed.
Journal ArticleDOI
Discovery of Drug Synergies in Gastric Cancer Cells Predicted by Logical Modeling.
Åsmund Flobak,Anaïs Baudot,Elisabeth Remy,Liv Thommesen,Denis Thieffry,Martin Kuiper,Astrid Lægreid +6 more
TL;DR: A dynamical model representing a cell fate decision network in the AGS gastric cancer cell line is developed, demonstrating that a model predictive of combinatorial drug effects can be inferred from background knowledge on unperturbed and proliferating cancer cells.
References
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Journal ArticleDOI
Gastric adenocarcinoma: review and considerations for future directions.
TL;DR: This update reviews the epidemiology and surgical management, and the controversies of gastric adenocarcinoma, and provides the relevance of outcome data to surgical decision-making and discusses the application of gene-expression analysis to clinical practice.
Journal ArticleDOI
Exosomal transfer of tumor-associated macrophage-derived miR-21 confers cisplatin resistance in gastric cancer cells
TL;DR: It is shown that M2 polarized macrophages promoted cisplatin (DDP) resistance in gastric cancer cells and exosomes derived from M2 macrophage (M2-exos) are involved in mediating the resistance to DDP.
Journal ArticleDOI
Exosomes derived from human mesenchymal stem cells confer drug resistance in gastric cancer
Runbi Ji,Bin Zhang,Xu Zhang,Jianguo Xue,Xiao Yuan,Yongmin Yan,Mei Wang,Wei Zhu,Hui Qian,Wenrong Xu +9 more
TL;DR: It is found that MSC-exosomes significantly induced the resistance of gastric cancer cells to 5-fluorouracil both in vivo and ex vivo, and Targeting the interaction between MSCs and cancer cells may help improve the efficacy of chemotherapy in Gastric cancer.
Journal ArticleDOI
PARP inhibitor combination therapy.
TL;DR: Both the pre-clinical and clinical evidence for the utility of such combinations are summarized and the future prospects and challenges for PARP inhibitor combinatorial therapies are discussed.
Journal ArticleDOI
Discovery of Drug Synergies in Gastric Cancer Cells Predicted by Logical Modeling.
Åsmund Flobak,Anaïs Baudot,Elisabeth Remy,Liv Thommesen,Denis Thieffry,Martin Kuiper,Astrid Lægreid +6 more
TL;DR: A dynamical model representing a cell fate decision network in the AGS gastric cancer cell line is developed, demonstrating that a model predictive of combinatorial drug effects can be inferred from background knowledge on unperturbed and proliferating cancer cells.