Weight Regain 10 Years After Roux-en-Y Gastric Bypass

TLDR: Patients submitted to Roux-en-Y gastric bypass presented weight regain, which increased over time, and age, iron deficiency, and time since surgery were associated with weight regain in the long-term follow-up.

Abstract: This study aims to investigate weight regain and the associated variables 10 years after Roux-en-Y gastric bypass This retrospective study recruited patients submitted to Roux-en-Y gastric bypass (N = 166) for a 10-year follow-up The following variables were investigated: body mass index (BMI), percentage of excess weight loss (%EWL), weight regain (WR), and percentage of weight regain (%WG) The chi-squared test or Fisher’s exact test compared proportions, and the Mann-Whitney test compared numerical measurements between the groups Analysis of variance (ANOVA) compared the measurements over time The significance level was set at 5 % The sample had a mean age of 3959 ± 1169 years, and females prevailed (717 %) In the long-term follow-up, 41 % of the patients had weight regain Seventy-two months after surgery, excess weight, preoperative BMI, gender, age, nutritional monitoring, and iron deficiency did not explain weight regain Younger patients had regained significantly more weight 96 (p = 0008) and 120 months (p = 0004) after surgery than older patients Patients who regained weight had ferritin <15 μg/dL 96 months after surgery (p = 0019) Patients submitted to Roux-en-Y gastric bypass presented weight regain, which increased over time Age, iron deficiency, and time since surgery were associated with weight regain in the long-term follow-up