Citations
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Journal ArticleDOI
Diabetes mellitus and birth defects
Adolfo Correa,Suzanne M. Gilboa,Lilah M. Besser,Lorenzo D. Botto,Cynthia A. Moore,Charlotte A. Hobbs,Mario A. Cleves,Tiffany Riehle-Colarusso,D. Kim Waller,E. Albert Reece +9 more
TL;DR: Pregestational diabetes mellitus was associated with a wide range of birth defects; GDM wasassociated with a limited group ofBirth defects.
Journal ArticleDOI
Fetal cyclic motor activity in diabetic pregnancies: sensitivity to maternal blood glucose.
TL;DR: The pattern of results suggests that disruption of the temporal organization of spontaneous fetal motor activity in pregnancies complicated by maternal diabetes represents an acute response to fluctuations in the metabolic environment rather than an alteration of CM development.
Journal ArticleDOI
Preconception care of women with diabetes.
TL;DR: The purpose of this article is to provide nurses with current clinical assessment and management strategies of women with diabetes in order to implement a comprehensive individualized preconception plan of care.
Journal ArticleDOI
Adverse pregnancy outcomes in women with diabetes
TL;DR: The aim of this review is to reinforce the need to improve the knowledge on reproductive health of women with diabetes during gestation and to understand what are the reasons for them failing to attend for prepregnancy care programs, to understand the underlying mechanisms of adverse fetal and maternal outcomes.
Journal ArticleDOI
Risk of specific congenital abnormalities in offspring of women with diabetes.
Gunnar Lauge Nielsen,Bente Mertz Nørgård,E. Puho,Kenneth J. Rothman,Henrik Toft Sørensen,Andrew E. Czeizel +5 more
TL;DR: To assess the extent to which the increased risk of congenital abnormalities seen in women with pre‐gestational insulin‐treated diabetes mellitus is unspecific or related to the embryology of specific organs.
References
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Journal ArticleDOI
Malformations in Infants of Diabetic Mothers Occur Before the Seventh Gestational Week: Implications for Treatment
TL;DR: Developmental morphologic dating shows that the significantly more common congenital malformations in infants of diabetic mothers occur before the seventh week of gestation, which suggests that any therapeutic intervention aimed at decreasing the incidence of congenital Malformations must be instituted during the critical early period.
Journal ArticleDOI
Prevention of Congenital Malformations in Infants of Insulin-dependent Diabetic Mothers
Kurt Fuhrmann,Horst Reiher,Klaus Semmler,Friedericke Fischer,Michael Fischer,Eberhard Glöckner +5 more
TL;DR: It is indicated that reasonable metabolic control started before conception and continued during the first weeks of pregnancy can prevent malformations in infants of diabetic mothers.
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Preconception care of diabetes. Glycemic control prevents congenital anomalies.
John L. Kitzmiller,Laurence A. Gavin,Gary D. Gin,Lois Jovanovic-Peterson,Elliott K. Main,William D. Zigrang +5 more
TL;DR: It is concluded that education and intensive management for glycemic control of diabetic women before and during early pregnancy will prevent excess rates of congenital anomalies in their infants.
Journal ArticleDOI
Lack of relation of increased malformation rates in infants of diabetic mothers to glycemic control during organogenesis.
James L. Mills,Robert H. Knopp,Simpson Jl,Lois Jovanovic-Peterson,Boyd E. Metzger,L. B. Holmes,J. H. Aarons,Z Brown,George F. Reed,Frederick R. Bieber +9 more
TL;DR: The more favorable outcome seen in the former group as compared with the late-entry group justifies the attempt to achieve good metabolic control around the time of conception, and the data suggest that more sensitive measures are needed to identify the teratogenic mechanisms, or that not all malformation can be prevented by good glycemic control.
Journal ArticleDOI
Diabetes and Embryonic Malformations: Role of Substrate-Induced Free-Oxygen Radical Production for Dysmorphogenesis in Cultured Rat Embryos
Ulf J. Eriksson,L. A. Håkan Borg +1 more
TL;DR: The findings implicate the embryonic mitochondria as a likely site for enhanced substrate-induced production of free-oxygen radicals mediating the teratogenic effect of a diabetic environment and emphasizes the need for an extended metabolic surveillance of pregnant diabetic women.