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How to increase prolactin receptors? 

Prolactin cell
Receptor
Prolactin
Hypophysectomy
Prolactin receptor

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Papers (10)Insight
Journal Article•DOI
Regulation of prolactin receptor glycosylation and its role in receptor location
Franklyn F. Bolander
25 Mar 1999-Molecular and Cellular Endocrinology
8 Citations
These data suggest that prolactin receptors are retained intracellularly because of their incomplete N-glycosylation and that NO triggers their redistribution by stimulating the completion of this process, in part by increasing NAG transferase I activity.
Journal Article•DOI
Prolactin receptors in rat liver: possible induction by prolactin.
Barry I. Posner, Paul A. Kelly, Henry G. Friesen 
04 Apr 1975-Science
257 Citations
Our observations suggest that prolactin induces its own receptor.
Journal Article•DOI
Prolactin stimulation of prolactin receptors in rat liver.
Mark E. Costlow, Robert A. Buschow, William L. McGuire 
01 Nov 1975-Life Sciences
95 Citations
As little as 0.5 mg prolactin significantly increases receptors, while doses above the 2 mg optimum are apparently less effective.
Open access•Journal Article•DOI
Characterization of prolactin receptors in pig mammary gland.
S. Sakai, M Katoh, P Berthon, P A Kelly 
15 Dec 1984-Biochemical Journal
38 Citations
The present demonstration shows that particulate prolactin receptors from a domestic animal can be solubilized and purified without losing the original properties of high affinity and binding specificity for hormones.
Journal Article•DOI
Prolactin regulation of cryptic prolactin receptors in cultured rat mammary tumor cells
Mark E. Costlow, Amie Hample 
01 Mar 1984-Journal of Cellular Physiology
6 Citations
In this report we demonstrate that prolactin regulates the level of cryptic receptors.
Journal Article•DOI
Prolactin receptor signal transduction pathways and actions determined in prolactin receptor knockout mice.
Paul A. Kelly, Nadine Binart, Michael Freemark, B. Lucas, Vincent Goffin, Brigitte Bouchard 
01 May 2001-Biochemical Society Transactions
36 Citations
Prolactin-receptor-deficient mice are a good model in which to study the various actions of prolactin.
Journal Article•DOI
Prolactin Receptor Gene Diversity: Structure and Regulation
Zhang-Zhi Hu, Li Zhuang, Maria L. Dufau 
01 Apr 1998-Trends in Endocrinology and Metabolism
30 Citations
It is now clear that cellular responsiveness to prolactin can be regulated through differential promoter control of the expression of the surface receptors for prolactin in different target tissues.
Open access•Journal Article•DOI
Human prolactin receptors are insensitive to mouse prolactin: implications for xenotransplant modeling of human breast cancer in mice.
Fransiscus E. Utama, LeBaron Mj, Neilson Lm, Ahmed S. Sultan, Albert F. Parlow, Kay Uwe Wagner, Hallgeir Rui 
01 Mar 2006-Journal of Endocrinology
64 Citations
We now show both recombinant and natural pituitary-derived mouse prolactin to be a poor agonist for human prolactin receptors.
Open access•Journal Article•DOI
Solution structure of human prolactin
Kaare Teilum, Jeffrey C. Hoch, Vincent Goffin, Sandrina Kinet, Joseph A. Martial, Birthe B. Kragelund 
26 Aug 2005-Journal of Molecular Biology
103 Citations
Thus, our results lead to improved understanding of the prolactin-prolactin receptor interaction.
Journal Article•DOI
Preferential establishment of a slowly dissociable component in plasma membrane compared to intracellular prolactin receptors.
Paul A. Kelly, Jean Djiane, Gilles Leblanc 
01 Feb 1983-Experimental Biology and Medicine
12 Citations
Therefore, it appears that receptors with lower affinity at the cell periphery are those involved in the initial mechanism of action of prolactin.

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