What are the key parameters affecting the growth and metabolism of yeasts?
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Key parameters influencing yeast growth and metabolism include temperature effects, metabolic pathway partitioning, cellular constraints, and intrinsic properties like strain type and culture medium. Temperature significantly impacts yeast metabolism, with Bayesian modeling revealing enzymes limiting growth at different temperatures . Metabolic pathway partitioning is crucial, with energy and electron carriers playing a key role in triggering pathways during growth . Cellular constraints, such as mitochondrial limitations under glucose limitation and cytosolic volume constraints under sugar excess, affect metabolic strategies and protein expression . Additionally, intrinsic properties like strain type, culture medium, and physiological state impact yeast growth quantitatively, necessitating detailed cybernetic modeling for optimization .
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| Key parameters affecting yeast growth and metabolism include compartment-specific proteome constraints, mitochondrial limitations under glucose scarcity, and cytosolic volume constraints during sugar excess, influencing metabolic strategies and protein expression. | |
11 Citations | Key parameters affecting yeast growth and metabolism include strain type, culture medium, physiological state of the inoculum, temperature, pH, and sugar concentration, as analyzed quantitatively in the study. |
| Key parameters affecting yeast growth and metabolism include compartment-specific proteome constraints, mitochondrial limitations under glucose scarcity, and cytosolic volume constraints during sugar excess, as predicted by the whole-cell model. | |
| Key parameters affecting yeast growth and metabolism are enzymatic thermal parameters. The study identifies temperature effects on individual proteins, highlighting squalene epoxidase as a critical enzyme in yeast thermosensitivity. | |
| The key parameters affecting the growth and metabolism of yeasts are components, energy (ATP/ADP), and electron carriers (NAD+/NADH) as highlighted in the predictive dynamic yeast model. |
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