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Simon J. Hubbard
Researcher at Manchester Academic Health Science Centre
Publications - 138
Citations - 10081
Simon J. Hubbard is an academic researcher from Manchester Academic Health Science Centre. The author has contributed to research in topics: Gene & Proteome. The author has an hindex of 46, co-authored 130 publications receiving 9540 citations. Previous affiliations of Simon J. Hubbard include University of Nottingham & Pennsylvania State University.
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Journal ArticleDOI
Sequence and comparative analysis of the chicken genome provide unique perspectives on vertebrate evolution
LaDeana W. Hillier,Webb Miller,Ewan Birney,Wesley C. Warren,Ross C. Hardison,Chris P. Ponting,Peer Bork,David W. Burt,Martien A. M. Groenen,Mary E. Delany,Jerry B. Dodgson,Asif T. Chinwalla,Paul F. Cliften,Sandra W. Clifton,Kimberly D. Delehaunty,Catrina Fronick,Robert S. Fulton,Tina Graves,Colin Kremitzki,Dan Layman,Vincent Magrini,John Douglas Mcpherson,Tracie L. Miner,Patrick Minx,William E. Nash,Michael N. Nhan,Joanne O. Nelson,Lachlan G. Oddy,Craig Pohl,Jennifer Randall-Maher,Scott M. Smith,John W. Wallis,Shiaw Pyng Yang,Michael N Romanov,Catherine M. Rondelli,Bob Paton,Jacqueline Smith,David Morrice,Laura M. Daniels,Helen G. Tempest,Lindsay Robertson,Julio S. Masabanda,Darren K. Griffin,Alain Vignal,Valerie Fillon,Lina Jacobbson,Susanne Kerje,Leif Andersson,Richard P. M. A. Crooijmans,Jan Aerts,Jan J. van der Poel,Hans Ellegren,Randolph B. Caldwell,Simon J. Hubbard,Darren Grafham,Andrzej M. Kierzek,Stuart McLaren,Ian M. Overton,Hiroshi Arakawa,Kevin J. Beattie,Yuri Bezzubov,Paul E. Boardman,James K. Bonfield,Michael D. R. Croning,Robert L. Davies,Matthew D. Francis,Sean Humphray,Carol Scott,Ruth Taylor,Cheryll Tickle,William Brown,Jane Rogers,Jean-Marie Buerstedde,Stuart A. Wilson,Lisa Stubbs,Ivan Ovcharenko,Laurie Gordon,Susan Lucas,Marcia M. Miller,Hidetoshi Inoko,Takashi Shiina,James C. Kaufman,Jan Salomonsen,Karsten Skjoedt,Gane Ka-Shu Wong,Jun Wang,Bin Liu,Jian Wang,Jun Yu,Huanming Yang,Mikhail Nefedov,Maxim Koriabine,Pieter J. deJong,Leo Goodstadt,Caleb Webber,Nicholas J. Dickens,Ivica Letunic,Mikita Suyama,David Torrents,Christian von Mering,Evgeny M. Zdobnov,Kateryna D. Makova,Anton Nekrutenko,Laura Elnitski,Pallavi Eswara,David C. King,Shan Yang,Svitlana Tyekucheva,Anusha Radakrishnan,Robert S. Harris,Francesca Chiaromonte,James Taylor,Jianbin He,Monique Rijnkels,Sam Griffiths-Jones,Abel Ureta-Vidal,Michael M. Hoffman,Jessica Severin,Stephen M. J. Searle,Andy Law,David Speed,D. Waddington,Ze Cheng,Eray Tüzün,Evan E. Eichler,Zhirong Bao,Paul Flicek,David Shteynberg,Michael R. Brent,Jacqueline M. Bye,Elizabeth J. Huckle,Sourav Chatterji,Colin N. Dewey,Lior Pachter,Andrei Kouranov,Zissimos Mourelatos,Artemis G. Hatzigeorgiou,Andrew H. Paterson,Robert Ivarie,Mikael Brandström,Erik Axelsson,Niclas Backström,Sofia Berlin,Matthew T. Webster,Olivier Pourquié,Alexandre Reymond,Catherine Ucla,Stylianos E. Antonarakis,Manyuan Long,J. J. Emerson,Esther Betrán,Isabelle Dupanloup,Henrik Kaessmann,Angie S. Hinrichs,Gill Bejerano,Terrence S. Furey,Rachel A. Harte,Brian J. Raney,Adam Siepel,W. James Kent,David Haussler,Eduardo Eyras,Robert Castelo,Josep F. Abril,Sergi Castellano,Francisco Camara,Genís Parra,Roderic Guigó,Guillaume Bourque,Glenn Tesler,Pavel A. Pevzner,Arian F.A. Smit,Lucinda Fulton,Elaine R. Mardis,Richard K. Wilson +174 more
TL;DR: A draft genome sequence of the red jungle fowl, Gallus gallus, provides a new perspective on vertebrate genome evolution, while also improving the annotation of mammalian genomes.
Journal ArticleDOI
A genetic variation map for chicken with 2.8 million single-nucleotide polymorphisms
Gane Ka-Shu Wong,Gane Ka-Shu Wong,Gane Ka-Shu Wong,Bin Liu,Jun Wang,Jun Wang,Yong Zhang,Yong Zhang,Xu Yang,Zengjin Zhang,Qingshun Meng,Jun Zhou,Dawei Li,Jingjing Zhang,Peixiang Ni,Songgang Li,Songgang Li,Longhua Ran,Heng Li,Jianguo Zhang,Ruiqiang Li,Shengting Li,Hongkun Zheng,Wei Lin,Guangyuan Li,Xiaoling Wang,Wenming Zhao,Jun Li,Chen Ye,Mingtao Dai,Jue Ruan,Yan Zhou,Yuanzhe Li,Ximiao He,Yunze Zhang,Jing Wang,Jing Wang,Xiangang Huang,Wei Tong,Jie Chen,Jia Ye,Jia Ye,Chen Chen,Ning Wei,Guoqing Li,Le Dong,Fengdi Lan,Yongqiao Sun,Zhenpeng Zhang,Zheng Yang,Yingpu Yu,Yanqing Huang,Dandan He,Yan Xi,Dong Wei,Qiuhui Qi,Wenjie Li,Jianping Shi,Miaoheng Wang,Fei Xie,Jianjun Wang,Xiaowei Zhang,Pei Wang,Yiqiang Zhao,Ning Li,Ning Yang,Wei Dong,Songnian Hu,Changqing Zeng,Wei-Mou Zheng,Bailin Hao,LaDeana W. Hillier,Shiaw Pyng Yang,Wesley C. Warren,Richard K. Wilson,Mikael Brandström,Hans Ellegren,Richard P. M. A. Crooijmans,Jan J. van der Poel,Henk Bovenhuis,Martien A. M. Groenen,Ivan Ovcharenko,Laurie Gordon,Laurie Gordon,Lisa Stubbs,Susan Lucas,Tijana Glavina,Andrea Aerts,Peter K. Kaiser,Lisa Rothwell,John R. Young,Sally L. Rogers,Brian A Walker,Andy van Hateren,James C. Kaufman,Nat Bumstead,Susan J. Lamont,Huaijun Zhou,Paul M Hocking,David R. Morrice,Dirk-Jan de Koning,Andy Law,Neil Bartley,David W. Burt,Henry D. Hunt,Hans H. Cheng,Ulrika Gunnarsson,Per Wahlberg,Leif Andersson,Leif Andersson,Ellen Kindlund,Martti T. Tammi,Martti T. Tammi,Björn Andersson,Caleb Webber,Chris P. Ponting,Ian M. Overton,Paul E. Boardman,Haizhou Tang,Simon J. Hubbard,Stuart A. Wilson,Jun Yu,Jun Yu,Jian Wang,Jian Wang,Huanming Yang,Huanming Yang +126 more
TL;DR: This map is based on a comparison of the sequences of three domestic chicken breeds with that of their wild ancestor, red jungle fowl, and indicates that at least 90% of the variant sites are true SNPs, and at least 70% are common SNPs that segregate in many domestic breeds.
Journal ArticleDOI
Global Translational Responses to Oxidative Stress Impact upon Multiple Levels of Protein Synthesis
Daniel Shenton,Julia B. Smirnova,Julian N. Selley,Kathleen M. Carroll,Simon J. Hubbard,Graham D. Pavitt,Mark P. Ashe,Chris M. Grant +7 more
TL;DR: In this paper, the authors analyzed the regulation of protein synthesis in response to oxidative stress induced by exposure to H2O2 in the yeast Saccharomyces cerevisiae.
Journal ArticleDOI
Molecular recognition. Conformational analysis of limited proteolytic sites and serine proteinase protein inhibitors.
TL;DR: Conformational parameters studied include main-chain torsion angles, root-mean-square fits, accessibility, mobility and protrusion indices, as well as being typically flexible regions of structure, as denoted by elevated temperature factors from crystallographic determinations.