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What is fst? 

Mutation rate
RF power amplifier
Trophoblast
Follistatin
Decidua
Best insight from top research papers

FST, also known as Follistatin, plays diverse roles in different biological contexts. In the context of placental development, FST is crucial for promoting trophoblast migration and invasion, potentially through enhanced JNK signaling. In the realm of breast cancer, low FST expression is associated with poor prognosis in triple-negative breast cancer (TNBC), influencing proliferation, migration, and invasion of TNBC cell lines. Moreover, FST has been extensively used as a genetic differentiation measure in populations, reflecting genetic variation and gene flow among populations . These diverse roles of FST highlight its significance in various biological processes, ranging from placental development to cancer progression and genetic studies.

Answers from top 4 papers

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Papers (4)Insight
Open access•Journal Article•DOI
High Power and Reliable SPST/SP3T RF MEMS Switches for Wireless Applications
Jitendra Pal, Yong Zhu, Junwei Lu, Dzung Viet Dao, Fahimullah Khan 
18 Jul 2016-IEEE Electron Device Letters
24 Citations
FST in the context of the research paper refers to the fabricated SPST and SP3T RF MEMS switches for high power and reliable wireless applications.
Open access•Journal Article•DOI
A clever solution to a vexing problem.
Michael C. Whitlock
01 Jul 2015-Molecular Ecology
2 Citations
FST is a measure of genetic differentiation between populations, influenced by mutation rates relative to migration rates, impacting the reliability of estimates in genetic studies.
Open access•Journal Article•DOI
Follistatin Is a Novel Chemoattractant for Migration and Invasion of Placental Trophoblasts of Mice
Jing Li, Yanjun Qi, Ke Yang, Linjing Zhu, Xueling Cui, Zhonghui Liu 
29 Nov 2022-Cells
1 Citations
FST, follistatin, is identified as a chemoattractant promoting migration and invasion of placental trophoblasts in mice, crucial for placental development and maintenance of pregnancy.
Open access•Journal Article•DOI
Down-regulated FST expression is involved in the poor prognosis of triple-negative breast cancer.
Sainan Liu, Bin Liu, Qian Zhao, Jikang Shi, Yulu Gu, Yanbo Guo, Yong Li, Yunkai Liu, Yi Cheng, Yichun Qiao, Yawen Liu 
17 May 2021-Cancer Cell International
4 Citations
Follistatin (FST) is a regulatory protein that influences apoptosis, proliferation, migration, and invasion in triple-negative breast cancer, impacting patient prognosis and serving as a potential biomarker.

Related Questions

What is fst populations?5 answersFST, or Fixation Index, is a crucial parameter in evolutionary genetics that quantifies genetic differentiation within and among populations. It provides insights into the structure of genetic variation and the impact of evolutionary processes on populations. FST values can be estimated globally, between pairs of populations, or even population-specific, reflecting deviations from ancestral populations and aiding in understanding population structures and evolutionary histories. Correcting allele frequencies using FST values enhances the accuracy of likelihood ratio calculations in forensic DNA analysis. By integrating population-specific FST estimates with pairwise FST values, a comprehensive picture of both current population structures and evolutionary histories can be obtained, aiding in various population genomics studies.
Why use f statistics?4 answersThe F-statistic is used for various purposes in different fields. In the context of embedded systems, the F-statistic is used to isolate measurement configurations that are sensitive to targeted chip processes. High F-values indicate that the variation in the target process is a major contributor to the measured signals, while background processes and measurement uncertainty have a minor impact. In the field of electromagnetic side-channel analysis, the F-statistic is used to accelerate the identification of vulnerabilities in cryptographic modules. High F-values indicate optimal measurement configurations that require collecting the fewest measurements to disclose sensitive information. In population genetics, the F-statistic is used to infer demographic history and analyze genetic variation across populations. It is used to estimate admixture rates, test for admixture and treeness, and construct admixture graphs. In the study of diesel engines, the F-statistic is used to assess the significance of changes in compression ratio on the specific enthalpy of exhaust gases. In high-dimensional linear subset regression, the F-statistic is used to test the significance of regression coefficients, even when the simple model is misspecified.
What is SFBT?4 answersSolution-Focused Brief Therapy (SFBT) is an approach that aims to help individuals find solutions to their problems in a practical, effective, and efficient manner. It focuses on the individual's desired outcome and utilizes their resources to move towards that outcome. SFBT is future-oriented and goal-directed, with an emphasis on the individual's strengths and abilities. It is a brief intervention model that can be used in various contexts, including dealing with cyberbullying behavior among adolescents, scholastic pressure and procrastination, psychological anxiety, especially during the COVID-19 outbreak, and trauma among survivors. SFBT involves a collaborative therapeutic relationship and utilizes strength- and resource-oriented questions to facilitate hope and subjective well-being. It is considered a positive and empowering approach that treats individuals as active participants in their own change process.
What is cfst?3 answersConcrete-filled steel tubes (CFST) are composite members used in civil engineering structures such as buildings, bridges, and towers. CFST columns consist of a hollow steel tube filled with concrete, providing superior strength, stiffness, and ductility. Design codes such as ACI, AISC, Chinese Standard, and EC4 have been proposed to predict the load-carrying capacity of CFST columns, but their accuracy varies. Experimental, numerical, and analytical studies have been conducted to investigate the flexural behavior of CFST members, with parameters such as steel corrugated plate dimensions found to significantly affect their behavior. The compressive behavior of concrete-encased CFST (CE-CFST) stub columns has also been studied, with initial stress on the steel tube shown to influence the failure mode and ultimate strength. CFST members have been extensively researched under impulsive loading, with superior resistance observed compared to hollow counterparts and reinforced concrete members.
What is financial technology?5 answersFinancial technology (FinTech) refers to the use of new technologies, such as artificial intelligence, blockchain, and cloud computing, in the delivery of financial services. It has expanded access to financial services and brought about long-term changes to societies and economies. FinTech encompasses various implementations and sectors, including stock analysis, stock recommendation, and credit intermediation. It has the potential to bring societal benefits, such as lower prices and expanded access to credit, but the current competition framework and organizational design of administrative agencies in the US have hindered its full potential. The growth of computerization in financial markets has significantly transformed the economics of finance and banking, with increasing automation and technological advances. Overall, FinTech represents the application of new technologies to revolutionize and improve financial services, with the potential for both positive and negative impacts on the financial sector and society as a whole.
What is Flet?5 answersFlet is a deep learning framework that is used for developing and deploying AIoT applications on the edge. It is evaluated based on its ease-of-use and performance. Flet-Edge is a full life-cycle evaluation tool designed and implemented to assess the performance of Flet. It collects and presents metrics related to programming complexity, deployment complexity, and runtime performance. The tool can automatically collect twelve metrics of training or inference tasks and output them in text or chart format. By observing the hierarchical roofline diagram provided by Flet-Edge, it is possible to optimize the software and hardware of deep learning.

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