scispace - formally typeset
Search or ask a question

What is the relationship between air quality and dyslipidemia? 


Best insight from top research papers

Long-term exposure to air pollution is associated with dyslipidemia, an important risk factor for cardiovascular diseases. Studies have shown that air pollutants, including particles with diameters ≤1 μm (PM1), particles with diameters ≤2.5 μm (PM2.5), particles with diameters ≤10 μm (PM10), nitrogen dioxide (NO2), and ozone (O3), are associated with increased levels of cholesterol (TC), triglycerides (TG), low-density lipoprotein cholesterol (LDL-C), and decreased levels of high-density lipoprotein cholesterol (HDL-C) . The association between air pollution and dyslipidemia is stronger in individuals with high lipid levels . Long-term exposure to air pollutants, especially PM1 and PM2.5, is associated with deleterious effects on blood lipid markers, including higher TC, TG, and LDL-C levels, and lower HDL-C levels . Additionally, exposure to air pollution can impair HDL function, including reduced cholesterol efflux capacity and antioxidant potential . These findings suggest that air pollution plays a role in the development of dyslipidemia and highlight the importance of air pollution prevention and control in reducing the burden of cardiovascular diseases .

Answers from top 5 papers

More filters
Papers (5)Insight
The provided paper does not directly address the relationship between air quality and dyslipidemia. The paper focuses on the association between ambient air pollution and HDL (high-density lipoprotein) dysfunction in healthy adults.
The provided paper does not directly address the relationship between air quality and dyslipidemia. The paper focuses on the relationship between air pollution and high-density lipoprotein (HDL) cholesterol and particle number.
The paper states that long-term exposure to ambient air pollution is associated with dyslipidemias, suggesting a deleterious lipidemic effect of air pollutants.
The paper states that long-term exposure to air pollution can promote dyslipidemia, along with other metabolic disorders, due to systemic inflammation and oxidative stress.
The paper states that long-term exposure to air pollutants is associated with increased blood lipid levels and a higher risk of dyslipidemia.

Related Questions

What is the relationship between hypothyroidism and dyslipidemia?5 answersHypothyroidism is associated with dyslipidemia, characterized by elevated levels of total cholesterol (TC), triglycerides (TG), and low-density lipoprotein cholesterol (LDL-C), as well as decreased levels of high-density lipoprotein cholesterol (HDL-C). The relationship between hypothyroidism and dyslipidemia has been widely investigated, and it has been observed that hypothyroidism induces dyslipidemia or exacerbates existing dyslipidemia. In patients with hypothyroidism, there is an increased risk of developing atherosclerosis, which can lead to coronary heart diseases (CHD). The exact mechanisms underlying the association between hypothyroidism and dyslipidemia are not fully understood, but it is believed that thyroid hormones play a crucial role in lipid and lipoprotein metabolism regulation. Therefore, it is recommended to screen for thyroid dysfunction in patients with dyslipidemia.
What is the relationship between obesity and dyslipidemia?5 answersObesity is strongly associated with dyslipidemia, which is a disorder of lipoprotein metabolism characterized by abnormal levels of cholesterol and triglycerides in the blood. Regional fat depots in the body have distinct regulation of fat storage and mobilization, and obesity is associated with increased triglyceride content in adipose tissue and blood. Various obesity indices, such as body mass index (BMI) and waist circumference (WC), have been used to measure obesity and predict dyslipidemia. Studies have shown that obesity based on BMI and WC measurements is better than percentage of body fat (%BF) in predicting dyslipidemia. Mendelian randomization analyses have provided evidence of a causal effect of higher BMI on the risk of dyslipidemia and type 2 diabetes (T2D). Obesity is also associated with dyslipidemia in children, with gender and age differences in lipid profiles observed. Overall, obesity is closely linked to dyslipidemia, and addressing obesity is important for the prevention and management of dyslipidemia-related complications, including cardiovascular disease.
What are the cardiovascular risk factors associated with hypertension and dyslipidaemia?5 answersCardiovascular risk factors associated with hypertension and dyslipidaemia include age, obesity, high blood pressure, and abnormal lipid levels.Age over 30 years was found to be a risk factor for dyslipidaemia in patients with diabetes alone.Abdominal obesity and physical inactivity were significantly associated with dyslipidaemia in geriatric Nigerians with essential hypertension.Hypertensive patients with poorly controlled blood pressure had worse atherogenic lipoprotein values and were more likely predisposed to atherosclerotic cardiovascular disease.Other risk factors for dyslipidaemia in hypertensive patients included male sex, increased body mass index, hypercholesterolaemia, hypo-high-density lipoprotein, hypertriglyceridaemia, and duration of HIV infection more than 10 years.These findings highlight the importance of screening and managing dyslipidaemia in patients with hypertension to reduce the risk of major cardiovascular events.
What is the role of the gut microbiome in the development of dyslipidemia?5 answersThe gut microbiome plays a significant role in the development of dyslipidemia. Studies have shown that gut microbiota and microbiota-related metabolites can affect lipid metabolism and contribute to dyslipidemia. The gut microbiota can alter lipoprotein lipase action, VLDL secretion, and plasma triglyceride levels, leading to dyslipidemia. Additionally, gut microbiota metabolites such as bile acids, lipopolysaccharide, and short-chain fatty acids have been implicated in the regulation of hyperlipidemia. Furthermore, interventions targeting the gut microbiota, such as prebiotics, probiotics, fecal microbiota transplantation, and natural herbal medicines, have shown efficacy in the treatment of hyperlipidemia. These findings highlight the potential therapeutic management of dyslipidemia by modulating the gut microbiome.
What are the effects of dyslipidemia on atherosclerosis?5 answersDyslipidemia, characterized by elevated LDL cholesterol, low HDL cholesterol, and/or elevated triglyceride levels, has significant effects on atherosclerosis. It is a major modifiable risk factor for the development and progression of atherosclerotic cardiovascular disease (ASCVD). Dyslipidemia leads to the accumulation of cholesterol within the artery walls, resulting in the formation of plaques and narrowing of the arteries. These plaques involve the deposition of cholesterol crystals and the proliferation of fibrous tissues and smooth muscle, leading to reduced blood flow to the heart and increased risk of cardiovascular events. Lifestyle interventions, such as regular aerobic exercise, a healthy diet, weight management, and abstinence from smoking, are important in managing dyslipidemia and reducing ASCVD risk. Additionally, lipid-lowering therapy, particularly statins, is recommended for individuals at moderate to high risk of ASCVD. Other hypolipidemic drugs, such as ezetimibe and PCSK9 inhibitors, are also gaining popularity in clinical practice.
What is the definition of dyslipidemia AHA?3 answers血脂异常是一种以脂蛋白代谢异常为特征的血脂异常。它可能是由遗传障碍或某些称为继发性血脂异常的疾病引起的。美国心脏协会 (AHA) 血脂异常管理指南侧重于降低心脏病发作和中风等心血管疾病的风险,而不是具体的治疗目标。该指南建议使用他汀类药物,这是一种降胆固醇的药物,因为事实证明,他汀类药物在降低动脉粥样硬化性心血管疾病(ASCVD)风险方面最有效。该指南还强调了采取有益心脏健康的生活方式来预防和控制高血胆固醇的重要性。总体而言,AHA将血脂异常定义为脂蛋白代谢异常,可以通过改变生活方式和使用他汀类药物来降低心血管疾病的风险来控制。