What metal promotes growth of mycobacterium?
Best insight from top research papers
Copper promotes the growth of Mycobacterium tuberculosis and Mycobacterium avium subspecies hominissuis .
Answers from top 4 papers
More filters
Papers (4) | Insight |
---|---|
The paper does not mention which metal promotes the growth of Mycobacterium tuberculosis. The paper focuses on the role of Sigma factor C in copper nutritional immunity. | |
The provided paper does not mention specifically which metal promotes the growth of Mycobacterium avium subspecies hominissuis (MAH). | |
The provided paper does not mention any specific metal that promotes the growth of Mycobacterium tuberculosis. | |
59 Citations | The paper does not mention any specific metal that promotes the growth of Mycobacterium. |
Related Questions
What is the growth rate of slow growing mycobacteria?5 answersThe growth rate of slow-growing mycobacteria can vary significantly. Studies have shown that slow-growing mycobacteria, such as Mycobacterium tuberculosis, exhibit a very slow growth rate, with a mean generation time (MGT) of around 69.3 hours. In contrast, fast-growing mycobacteria like Mycobacterium smegmatis have a much shorter generation time, leading to faster growth rates. The prevalence of slow-growing mycobacteria in hospital water samples ranged from 32.5% to 57.7%, indicating their presence in healthcare environments. Understanding the growth rates of different mycobacterial species is crucial for developing effective treatment strategies and controlling infections in clinical settings.
What are the molecular mechanisms behind isoniazid's ability to inhibit the synthesis of mycolic acid in mycobacteria?4 answersIsoniazid (INH) inhibits mycolic acid synthesis in mycobacteria through various molecular mechanisms. INH targets the enoyl ACP reductase InhA, a key enzyme in mycolic acid biosynthesis. Additionally, INH is activated by catalase-peroxidase (KatG) and inhibits mycolic acid production by impacting enzymes like β-ketoacyl ACP synthase (KasA) and enoyl acyl carrier protein (ACP) reductase. Interestingly, INH's bactericidal activity is linked to perturbations in the electron transport chain (ETC) and ATP levels, rather than solely through target inhibition, with involvement of mycobacterial cytochrome bc1, FoF1 ATP synthase, NADH dehydrogenases (NDHs), and succinate dehydrogenases (SDHs). These findings highlight the multifaceted mechanisms by which INH disrupts mycolic acid synthesis in mycobacteria, contributing to its efficacy as an anti-tubercular agent.
How do the environmental conditions in copper mines affect the growth and survival of bacteria?4 answersThe environmental conditions in copper mines can have significant effects on the growth and survival of bacteria. Studies have shown that metal pollution, such as increased copper concentrations, can alter the virulence of bacterial communities, leading to reduced diversity and productivity. Microbial communities in copper mines are influenced by various physicochemical conditions, with bacteria, particularly Acidiphilium and Acidisphaera, dominating in sediment and filamentous streamers. In the case of the Kilianstollen copper mine, heavy metal contamination has resulted in the colonization of subterranean rocks by Chloroflexi and Cyanobacteria, which are involved in redox cycling of transition metals. Long-term exposure to copper-containing surfaces can lead to the evolution of copper-resistant strains, with increased resistance to copper ions and antibiotics, but decreased production of biofilm and exoprotein. Additionally, the exposure of freshly fractionated copper-rich rock to mine water can result in leaching of copper, potentially caused by both abiotic and bacterial processes.
How does the presence of metal ions affect the stability of the yeast cell wall?5 answersThe presence of metal ions can affect the stability of the yeast cell wall. Metal nanoparticles used as antifungals can cause genomic and physiological changes, leading to the development of fungal superbugs. Metal ions, such as zinc, copper, iron, manganese, and silver, play a vital role in yeast metabolism and can act as cofactors on enzymes. In the case of a metal mixture, exposure to metals like Cd, Pb, and Zn can induce a loss of metabolic activity and proliferation capacity in yeast cells. The concentration of certain metal ions, such as calcium, magnesium, zinc, and manganese, can be significantly affected by the support used for yeast immobilization, such as calcium alginate and polyacrylate. Additionally, the presence of metal ions, such as selenium, in the yeast cell wall can be increased through a preparation method involving selenium-rich yeasts.
Does zinc have an effect on the growth of Mycoplasma pneumoniae?5 answersZinc has been shown to have an effect on the growth of Streptococcus pneumoniae, a bacterium that causes pneumonia. However, there is no information available in the provided abstracts regarding the effect of zinc on the growth of Mycoplasma pneumoniae.
What are the mechanisms by which copper ion induction affects fungi?5 answersCopper ion induction affects fungi through various mechanisms. Fungi can trap copper ions using cell-wall components, alter copper uptake, chelate or precipitate copper with secreted metabolites, and complex copper ions intracellularly using metallothioneins and phytochelatins. Copper has a general inducing effect on enzymes related to the metabolism of oxygen and oxygen derivatives in fungi, which is mediated by neither the formation of reactive oxygen species nor the interaction with copper-specific apoproteins. Black fungi, in particular, have unique features in regulating zinc and copper homeostasis, possibly due to the niches they inhabit. However, the specific mechanisms by which copper ion induction affects fungi have not been fully elucidated and require further investigation.