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What will happen when candida albicans grown in media contain glucose? 


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When Candida albicans is grown in media containing glucose, several outcomes can be observed. Glucose depletion can induce efficient sexual mating in C. albicans white cells, challenging the notion that the white-to-opaque switch is necessary for mating . Different culture media compositions can influence biofilm formation in C. albicans, with media rich in glucose and fetal bovine serum promoting robust biofilm production . Soybean cooking water has been identified as an effective alternative medium for Candida albicans growth, providing essential nutrients for fungal development . Lipid composition in C. albicans can be affected by the growth medium, potentially impacting drug susceptibility without altering morphological characteristics . Glucose concentrations in the media do not significantly affect the behavior of C. albicans biofilms on epithelial monolayers, suggesting that other mechanisms may be involved in tissue invasion .

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When Candida albicans is grown in media containing glucose, it does not significantly alter its behavior during tissue invasion, as shown by LDH release, cytokine levels, and biofilm structure.
When Candida albicans is grown in media containing glucose, it shows altered lipid composition but maintains most phenotypic properties, with some impact on drug susceptibility due to lipid changes.
When Candida albicans is grown in media containing glucose, it will utilize the glucose as a carbohydrate source for growth and development, as seen in the study using soybean cooking water.
Candida albicans grown in media containing glucose, especially with fetal bovine serum (FBS) supplementation, enhances in vitro biofilm production, as per the study findings.
Glucose depletion enables Candida albicans white cells to undergo efficient sexual mating by altering gene expression, suggesting mating can occur independently of the white-opaque switch in nature.

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