Showing papers on "Curcuma amada published in 2011"

Mango ginger (Curcuma amada Roxb.) – A promising spice for phytochemicals and biological activities

Abstract: Mango ginger (Curcuma amada Roxb.) is a unique spice having morphological resemblance with ginger but imparts a raw mango flavour. The main use of mango ginger rhizome is in the manufacture of pickles and culinary preparations. Ayurveda and Unani medicinal systems have given much importance to mango ginger as an appetizer, alexteric, antipyretic, aphrodisiac, diuretic, emollient, expectorant and laxative and to cure biliousness, itching, skin diseases, bronchitis, asthma, hiccough and inflammation due to injuries. The biological activities of mango ginger include antioxidant activity, antibacterial activity, antifungal activity, anti-inflammatory activity, platelet aggregation inhibitory activity, cytotoxicity, antiallergic activity, hypotriglyceridemic activity, brine-shrimp lethal activity, enterokinase inhibitory activity, CNS depressant and analgesic activity. The major chemical components include starch, phenolic acids, volatile oils, curcuminoids and terpenoids like difurocumenonol, amadannulen and amadaldehyde. This article brings to light the major active components present in C. amada along with their biological activities that may be important from the pharmacological point of view.

Phytochemical investigations and antibacterial activity of some medicinal plants against pathogenic bacteria

Abstract: The antibacterial activity of various solvent extracts of medicinal plants was evaluated against the human pathogenic bacteria Escherichia coli, Klebsiella pneumonia, Bacillus subtilis Bacillus cereus, Salmonella typhi, Enterobacter aerogenes and Staphylococcus aureus by agar cup diffusion method. Methanol extracts of Clerodendrum inerme L., Terminalia chebula Retz., Curcuma amada Roxb., Anacardium occidentale L., Duranta repens L., Eucalyptus camaldulenis Dehnh and Euphorbia cotinifolia L. showed significant activity. The petroleum ether and chloroform extracts of Terminalia chebula, Curcuma amada and Piper betel also showed promising results. The antibacterial activity of promising plant extracts when compared with standard drugs streptomycin and gentamycin recorded siginificant inhibition. Phytochemical analysis of the different extracts of the screened plants indicated the presence of flavanoids, terpinoids, tannins steriodas, alkaloids and glysocides. The positive results of screening of medicinal plants for antibacterial activity forms primary platform for further phytochemical and pharmacological studies.

Evaluation of antioxidant activity in ethanolic extracts of five curcuma species

Abstract: The Zingiberaceae, the largest family in the Zingiberales, comprises nearly 50 genera and 1,000 species and is pantropical, concentrated mainly in the old worl d, chiefly in Indo malaysia. Members of the family yield spices, dyes, perfumes, medicines and a number of ornamental species are cultivated for their showy flowers. Recently this plant has acquired great importance in the present - day world with its antiag ing, anticancer, anti - alzheimer’s diseases, antioxidant, and a variety of other medicinal properties due to its significant potential. The present study aims at comparing the antioxidant activity of five Curcuma species namely Curcuma longa , C urcuma zedoar ia, C urcuma angustifolia, C urcuma aromatica and Curcuma amada based on their curcumin and phenol content. In our studying C.longa exhibited the highest antioxidant activity 74.61 ±0.02% at IC 50 value 24 µg/ml followed by C.zedoaria (63.27 ±0.06%), C.angustifolia (5 8.35 ±0.06%), C.aromatica ( 55.3 8±0.06%) and C.amada ( 52.61 ±0.02%) . Antioxidant activity in four species except C.angustifolia has strong correlation with curcumin and phenol content. However C.angustifolia may be active due to high aromatic oil content like eugenol, palmitic and camphor et c. T he natural oxides of curcuma species can be explained in the field of pharmaceutical areas for their use s in modern health care as phytoprotectants.

Cloning and characterization of PR5 gene from Curcuma amada and Zingiber officinale in response to Ralstonia solanacearum infection.

Abstract: Ginger (Zingiber officinale Roscoe), is an important spice crop that is badly affected by Ralstonia solanacearum wilt. Ginger does not set seed and sexual recombination has never been reported. In spite of extensive search in its habitats, no resistance source to Ralstonia induced bacterial wilt, could be located in ginger. Curcuma amada Roxb. is a potential donor for bacterial wilt resistance to Z. officinale, if the exact mechanism of resistance is understood. Pathogenesis-related (PR)-5 proteins are a family of proteins that are induced by different phytopathogens in many plants and share significant sequence similarity with thaumatin. Two putative PR5 genes, CaPR5 and ZoPR5, were amplified from C. amada and ginger, which encode precursor proteins of 227 and 224 amino acid residues, respectively, and share high homology with a number of other PR5 genes. The secondary and three-dimensional structure comparison did not reveal any striking differences between these two proteins. The expression of Ca and ZoPR5s under R. solanacearum inoculation was analyzed at different time points using quantitative real-time PCR (qRT-PCR). Our results reveal that CaPR5 is readily induced by the bacterium in C. amada, while ZoPR5 induction was very weak and slow in ginger. These results suggest that the CaPR5 could play a role in the molecular defense response of C. amada to pathogen attack. This is the first report of the isolation of PR5 gene from the C. amada and Z. officinale. Promoter analysis indicates the presence of a silencing element binding factor in ZoPR5-promoter, but not in CaPR5. Prospective promoter elements, such as GT-1 box and TGTCA, implicated as being positive regulatory elements for expression of PR proteins, occur in the 5′-flanking sequences of the CaPR5. Transient GUS expression study confirms its action with a weaker GUS expression in ginger, indicating that the PR5 expression may be controlled in the promoter.

Curcuma longa leaves exhibits a potential antioxidant, antibacterial and immunomodulating properties

Abstract: The use of herbs to treat illness has its roots in an ancient holistic healing tradition that originated in Asia more than 3000 years ago Plants rich in a wide variety of secondary metabolites like tannins, terpanoids, alkaloids, alkaloids and flavonoids, which have been found in vitro to have antimicrobial and antioxidant propertiesTurmeric, a representative of plant genus Curcuma, is the member of ginger family, Zingiberaceae There are five different varieties we have taken Curcuma amada, Curcuma aromatica, Curcuma longa, Curcuma zeodaria, Curcuma caesia The active substance of turmeric is the polyphenol curcumin, also known as natural yellow 3 It exists at atleast 2 tautomeric forms, keto and enol It has aroma and flavour and it is used in cosmetics and food additive besides medicinal properties The present study is a new attempt in leaves segments of the plant Curcuma longa to prove the medicinal potential of the whole plant This study also includes the comparison of the different species of Curcuma The active constituents of turmeric are the flavonoid curcumin and volatile oils including turmeron, atlanton and gingibaron Our experiments are based on 50% methanolic extract of Curcuma leaves to perform anti bacterial, anti oxidant and immunomodulating properties The antibacterial activity has been done by the help of Disc Diffusion Susceptibility Testing (Kirby-Bauer Method) against four species of bacteria which include Bacillus cereus, Diploccocus pneumoneae, Streptococcus pyrogens & Micrococcus glutamicus Antioxidant activity has been detected by the Fenton’s reaction Immunomodulation activity has been seen in curcuma leaves The results of the present study reveal that all the five species of curcuma exhibit an antioxidant activity and antibacterial activity on different concentration of leave extract The extract was found to increase the phagocytic activity of macrophages against yeast cells However, the best activity has been revealed by curcuma longa among the all species of curcuma In near future the pharmaceuticals studies can be extended to prove its tremendous medicinal properties in case of drug preparation for immune cell properties enhancement and to prove its potential value unlike Curcuma rhizome Keywords:— Curcuma Longa, Curcuma Amada, Curcuma Aromatica, Immounomodulation, Curcumin

Cytotoxicity, Platelet Aggregation Inhibitory and Antioxidant Activity of Curcuma amada Roxb. Extracts

Abstract: Mango ginger (Curcuma amada Roxb.) is a unique spice having morphological resemblance to ginger but imparts raw mango flavour. The sequential extraction of mango ginger rhizome powder was carried out using hexane, chloroform, ethyl acetate, acetone, methanol and water. The phenolic content was the highest in methanol extract, followed by acetone, ethyl acetate and water extracts. Among these, chloroform extract exhibited high lipid peroxidation inhibitory activity and metal chelating activity, whereas ethyl acetate extract showed high DPPH radical scavenging activity and superoxide radical scavenging activity. Mango ginger extracts also showed potential platelet aggregation inhibitory activity and cytotoxicity properties.

Environmentally safe in vitro regeneration protocol for Curcuma, Kaempferia and Zingiber

Abstract: This study is a pioneer report on the development of an environmentally safe in vitro regeneration protocol for Curcuma , Kaempferia and Zingiber . The germplasm of the species was collected from Myanmar, a Southeast Asian country, rich in unexplored Zingiberaceae genetic resources. Rhizome buds were directly regenerated on the Murashige and Skoog medium containing a growth regulator, 6-benzyladenine and a commercial fungicide, Benlate (50% of Benomyl). The pre-treatment protocol did not contain HgCl2, a toxic pollutant for Curcuma amada, Curcuma longa, Zingiber barbatum and Kaempferia galanga. Plantlets were regenerated from the buds without any intervention of the callus phase. The contamination free survival of the bud explants from Curcuma, Zingiber and Kaempferia was more than 75, 57 and 53%, respectively. Buds from immature rhizomes were difficult to regenerate on the media, as well as resulted in higher contamination percentages while the buds from mature rhizomes efficiently regenerated with very few contamination percentages. The contamination was in the range of 0 to 39% among the different accessions. This was also the first report of direct in vitro regeneration of plantlets from Z. barbatum bud explants. The protocol was cost-beneficial, time saving and effective for the conservation of Zingiberaceae genetic resources. Key words : Conservation, regeneration, Zingiberaceae , tissue culture, Curcuma, Zingiber , Myanmar.

Curcuma amada roxb. rhizome extract modulates cellular a'd humoral immu'e system

Abstract: Summary Immunomodulatory effect of Curcuma amada Roxb.was assessed using In-vitro Phagocytosis activity, delayed type hypersensitivity test and Hem agglutination test. Extraction of plant rhizome was performed using petroleum ether, chloroform, acetone and alcohol. Alcoholic extract showed maximum effect in invitro assay thus it was used for in-vivo investigat ion at 400 mg/kg, 200 mg kg and 100 mg/kg. Extract showed significant immunomodulatory effect at all selected dose.

Tie2 ACTIVATOR AND LYMPH VESSEL STABILIZER

Abstract: PROBLEM TO BE SOLVED: To provide a novel Tie2 activator, and a stabilizer of a lymph vessel containing the activator.SOLUTION: The novel Tie2 activator contains a plant of Curcuma amada ROXB. or an extract thereof and/or Panax Ginseng or an extract thereof. The stabilizer of a lymph vessel contains the activator.