Showing papers on "Gelatin published in 1987"

Ordnance gelatin for ballistic studies. Detrimental effect of excess heat used in gelatin preparation.

Abstract: Most users of ordnance gelatin for ballistics studies are apparently unaware of the detrimental effects on this tissue simulant's properties caused by excess heating in reconstitution of the gelatin powder. Material published by the Gelatin Manufacturers Institute of America states that heating gelatin above 40 degrees C can be detrimental to its properties. The manufacturer of type 250 A Ordnance Gelatin does not include directions for preparation with the gelatin powder. Directions that can be obtained by contacting the manufacturer fail to give any recommendations on the amount of heat applied during gelatin preparation and do not mention the detrimental effects of excess heat. These oversights are corrected in the revised set of directions included in this article.

Process for coating gelatin capsules

Abstract: This invention provides a new gelatin capsule formulation and subcoating for producing soft gelatine capsules having better mechanical strength and an improved capacity for adhering to known coating compositions, particularly enteric coating compositions. The finished capsule shell formulation comprises gelatin 65%-70%, glycerin 22%-25% and water 8%-10% and the subcoating is a suspension of hydroxypropyl methylcellulose. The subcoating may also be used to manufacture improved enteric coated hard gelatin capsules.

Gelatin-encapsulated controlled-release composition

Abstract: A controlled-release pharmaceutical unit dosage form is pro­vided comprising a gelatin capsule enclosing a solid matrix formed by the cation-assisted gellation of a liquid fill incorporating a vegetable gum and a pharmaceutically-active compound, as well as methods for the preparation thereof.

Microcapsules based on gelatin and polysaccharides and process for obtaining same

Abstract: This invention relates to microcapsules based on gelatin and anionic polysaccharides of low molecular weight which may contain solid or liquid matters, prepared by coacervation. The aqueous polysaccharide solutions which may be used present a low viscosity, the value of which is a function of the nature of the polysaccharide; for a concentration of 15 g/l, it is, at 75° C., generally between 1 and 20 mPa.s. These polysaccharides are depolymerization products of natural products:alginates, carragheenans, pectins and pectates, carboxymethylcelluloses, carboxymethylguars and carboxymethyl starches. The microcapsules may be isolated and dried.

Crystalline hydrate of oral cephalosporin and its composition

Abstract: An antibacterial, 7β-[(Z)-2-(2-aminothiazol-4-yl)-4-carboxybut-2-enoylamino]-3-cephem-4-carboxylic acid is stable in a (di or tri)-hydrate crystal form. A pharmacologically effective amount of this hydrate is filled in a gelatin hard capsule sealed by a band of gelatin to make a stable composition for clinical use after storage for a long time.

Process for making a spray-dried, directly-compressible vitamin powder comprising unhydrolyzed gelatin

Abstract: A process for making a directly-compressible vitamin powder utilizes a conventional spray-dryer. The resulting powder is comprised of a fat-soluble vitamin, a water-soluble carbohydrate, and a gelatin having a bloom number between 30 and 300.

Microcapsules based on gelatin and on polysaccharide, and their preparation

Abstract: Microcapsules based on gelatin and anionic polysaccharide of low molecular mass which may contain solid or liquid substances, prepared by coacervation. … The aqueous solutions of the polysaccharides which may be employed have a low viscosity whose value is a function of the nature of the polysaccharide; in the case of a concentration of 15 g/l it is generally between 1 and 20 mPa s at 75 DEG C. … These polysaccharides are products of depolymerisation of natural products: alginates, carrageenans, pectins and pectates, carboxymethyl celluloses, carboxymethyl guars and carboxymethyl starches. … The microcapsules may be isolated and dried.

Interactive Precipitation between Graded Peptides from Gelatin and Specific Grape Tannin Fractions in Wine-like Model Solutions

Abstract: Peptides isolated from gelatin hydrolysates purified with repeated dialysis and gel-permeation chromatography were mixed in aqueous alcoholic solutions of tartaric acid resembling wine with monomeric catechin or dimeric and oligomeric condensed tannin fractions from grape seeds. Precipitation did not increase significantly after the first day at 15°C. Exposure to air or nitrogen in the headspace made no difference in the results in tests up to two weeks. Increasing ethanol content decreased precipitation, but glucose and KCl had no effect. Although the largest peptide fraction caused haze, the smallest peptide fraction (2000 MW) was most effective in producing clarification by precipitation. Monomeric or dimeric flavonoids did not readily precipitate with the peptides but did interfere with precipitation by tannin. Completeness of precipitation was diminished by increasing acid in the range pH 4.5 to 2.5 suggesting that hydrogen bonding, at least with regard to protonation of the phenols, is not the only mechanism.

Gelatin capsules and method of preparing same

Abstract: Gelatin capsules, consisting of a capsule sheath and a capsule filling, the capsule sheath consisting of gelatin, optionally a plasticizer and further additives, and the capsule filling containing active substances and/or dietectic agents and, optionally, further additives and a liquid or powder, in the capsule sheath additionally contain an additive of at least 1% by weight of an agent which in the pure state is capable of absorbing water in an amount of at least 10% by weight of its own weight without undergoing a change in its appearance.

Method for rapid crosslinking of a protein

Abstract: The present invention relates to a method for the rapid crosslinking of a protein. More particularly, the protein is gelatin. The gelatin is crosslinked by combining a water miscible alcohol and acetaldehyde to the gelatin so that a moist intimate mixture results. Preferably, a mixture of gelatin, alcohol, and an oil-soluble vitamin (e.g. vitamin A) is crosslinked by the addition of acetaldehyde. The crosslinking of gelatin serves to stabilze the vitamin during conditions of high shearstress, as found in pelleting and extrusion operations involved in food and feed proecessing. Most preferably, a spray-congealed mixture of gelatin, vitamin A oil, sorbitol, and water are subjected to acetaldehyde vapors so that rapikd crosslinking of the gelatin occurs.

Vessel and prosthesis impregnated with diisocyanate crosslinked gelatin

Abstract: The invention relates to vessel prostheses formed from a porous vascular prosthesis impregnated with diisocyanate crosslinked gelatin for sealing the pores.

Dry stabilized microemulsified omega-three acid-containing oils

Abstract: Storage-stable, bio-available, free-flowing, microemulsified, Omega-three acid-containing oil compositions in the form of microspheres and macrospheres, said compositions consisting essentially of (1) up to about 70% by weight of Omega-three acid-containing oil, and (2) gelatin, in which the oil is microemulsified by the gelatin; processes for their preparation; and product applications (including tablet-type solid forms, dry powders, and spoonable, drinkable emulsions).

Apparatus for manufacturing gelatin capsule and method therefor

Abstract: Apparatus for manufacturing gelatin capsules and method therefor are provided. The apparatus comprises a gelatin sheet forming mechanism which includes a rotatable cooling drum, a gelatin capsule forming mechanism which includes a pair of die rolls and a gelatin capsule recovery mechanism. The inner space of the cooling drum is provided with a coolant. The thickness of the gelatin sheet and the gap between the die rolls are numerically indicated respectively. The driving mechanism for the gelatin capsule recovery mechanism is independent from the other driving mechanism provided in the apparatus.

Improved diffraction efficiency of silver halide (sensitized) gelatin

Abstract: A modification of the silver halide (sensitized) gelatin process is described. We demonstrate a phase process utilizing commercially available photographic emulsions and processing which has the sensitometric properties of silver halide emulsion and the holographic performance characteristics found in dichromated gelatin-based processes.

Aqueous ink and process for its manufacture

Abstract: The invention relates to an aqueous ink for writing, drawing, or marking, which has as a dispersion stabilizer a degradation product of gelatin made by enzymatic action of a protease. The process of the invention is carried out by subjecting an aqueous gelatin solution to degradation by an enzyme, then inhibiting the enzyme, such as by heating to 90 degrees C. or above, before the degradation has proceeded to products which no longer have activity as dispersion stabilizers. Subsequently, colorants such as pigments can be added along with other desired additives.

Ethanol fill formulation for sofgels etc.

Abstract: Gelatin capsules of the type having an outer shell comprising gelatin and, optionally, a plasticizer, and a capsule filling, the filling containing at least one active substance and/or a dietetic agent or foodstuff as well as a solvent mixture, the solvent mixture containing about 5-50% by weight, preferably 10-30% by weight of ethanol and about 20-95% by weight, preferably 40-90% by weight of one or more of partial glycerides of fatty acids havig from 6 to 18 carbon atoms. The capsules are prepared by dissolving the active ingredients in the solvent mixture and filling the resulting mixture into the gelatin capsules.

Molded hydrophilic polymer

Abstract: A moldable non gelatin containing hydrophilic polymer composition containing between 5 and 25% water.

Co-immobilized coupled enzyme systems on nylon mesh capable of gluconic and pyruvic acid production

Abstract: The coupled enzyme systems glucose oxidase-catalase and lactate oxidase-catalase have been immobilized in a cross-linked gelatin matrix on a nylon mesh fabric. These immobilized enzyme systems can be used for the production of gluconic and pyruvic acids, respectively.

Thermostable muscle antigens suitable for use in enzyme immunoassays for identification of meat from various species.

Abstract: A method for the extraction of thermostable muscle antigens for use in enzyme immunoassays is described. The method yields antigens devoid of contaminating proteins which reduce the adsorption of the antigens on to the plate. The effect of such proteins is stimulated by the addition of gelatin. Gelatin (5 mg ml−1) results in 100% inhibition of the antigen adsorption on to the plate.

Optical memory card with versatile storage medium

Abstract: A data card for optical information featuring a gelatin layer having a thin black crust at the top of the layer. The crust is formed by developed black irregular oblong silver particles within the top 0.5 micron of the gelatin colloid matrix. The remainder of the colloid matrix is substantially clear gelatin and a reflective metallic layer is disposed below the gelatin. The strip is laminated into a wallet-size card and may be pre-patterned during formation of the crust with control indicia or pre-recorded data. User data may be recorded by modifying the black silver particles in the crust with a laser to expose the reflective underlayer. A laser or other light source is used to read data on the medium with optical contrast between the black surface metallic layer underlying the gelatin layer which can be observed in the recorded spots.