Showing papers on "Pyrroline published in 1988"
20 citations
TL;DR: In this article, the stereochemical assignments of the alcohol and the diol are discussed, and the stereochemistry assignments of both the alcohol (8) and diol (22) are discussed.
Abstract: 2,4-Diaryl-5,5-dimethyl-1-pyrroline 1-oxides (5)-(7) undergo smooth oxidation by concentrated nitric acid in acetonitrile to give the hydroxy ketones (9)-(11). Reduction of compound (10) with sodium borohydride gives the diol (22), which can be dehydrated to the oxo nitrone (23). The stereochemical assignments of the alcohol (8) and the diol (22) are discussed.
5 citations
TL;DR: In this paper, cyclohexane-1,2-acetonylcyclohexanone, 2 (R=CH3) was used to give the crossed-aldol product, 2-hydroxy-2.
Abstract: Acetone reacts with cyclohexane-1,2-dione, on refluxing in the presence of potassium carbonate, to give the crossed-aldol product, 2-hydroxy-2-acetonylcyclohexanone, 2 (R=CH3). Other methyl ketones...
4 citations
TL;DR: The 2,4-diaryl-1-pyrroline 1-oxides (4) can be converted into the related 2H pyrrole 1oxides by treatment with N-bromosuccinimide and anhydrous potassium carbonate as discussed by the authors.
Abstract: The 2,4-diaryl-1-pyrroline 1-oxides (4) can be converted into the related 2H-pyrrole 1-oxides (5) by treatment with N-bromosuccinimide and anhydrous potassium carbonate. Similar treatment of the 1-pyrroline 1-oxide (6) yielded the succinimido-substituted pyrroline (7). Selenium dioxide oxidation of the tetramethyl nitrone (8) under various conditions gave mixtures containing the compounds (10)-(12). Neither process provides a general conversion of 1-pyrroline 1-oxides into 2H-pyrrole 1-oxides.
3 citations
TL;DR: In this paper, ten 5,5-disubstituted-Δ1-pyrroline Noxides containing a chiral carbon at C-5 have been prepared and the stereospecificity of spin trapping has been demonstrated.
Abstract: Ten 5,5-disubstituted-Δ1-pyrroline N-oxides containing a chiral carbon at C-5 have been prepared and the stereospecificity of spin trapping has been demonstrated.
2 citations
Patent•
14 Jan 1988
2 citations
Patent•
17 Mar 1988
TL;DR: In this paper, a process for the preparation of 3,4-dihydro-2-pyridones of the formula and/or 3,pyrroline-2 -2-ones was described, in which R1 to R5 denote hydrogen, or alkyl, cycloalkyl, aralkyl or aryl radicals.
Abstract: Process for the preparation of 3,4-dihydro-2-pyridones of the formula and/or 3-pyrroline-2-ones of the formula in which R1 to R5 denote hydrogen, or alkyl, cycloalkyl, aralkyl or aryl radicals, in which 3-alkenylamides of the formula in which R1 to R5 have the abovementioned meaning, are reacted with carbon monoxide and hydrogen at temperatures of 80-150 DEG C and pressures of 1 to 300 bar in the presence of cobalt carbonyl and/or rhodium carbonyl complexes.
2 citations
TL;DR: Two-Cyano-1-pyrroline 1-oxides can be converted in high yield into cyclic hydroxamic acids by heating in aqueous hydrochloric acid as mentioned in this paper.
Abstract: 2-Cyano-1-pyrroline 1-oxides can be converted in high yield into the related cyclic hydroxamic acids by heating in aqueous hydrochloric acid. Eight examples are given.
2 citations
Patent•
30 Jun 1988
TL;DR: Alkyl 4-alkoxy-2-oxo-3-pyrroline-1 -acetates of formula (I) are new: (where R1 = Me or Et; R2 = 1-4C alkyl or benzyl) as discussed by the authors.
Abstract: Alkyl 4-alkoxy-2-oxo-3-pyrroline-1 -acetates of formula (I) are new: (where R1 = Me or Et; R2 = 1-4C alkyl or benzyl.
1 citations
1 citations
TL;DR: Vinylaziridine 2 underwent alkylative ring opening with trimethylsilyl iodide to furnish supinidine ethyl ester 4 from which isoretronecanol 7 and trachelanthamidine 9 were synthesized stereoselectively as discussed by the authors.
Abstract: Vinylaziridine 2 underwent alkylative ring opening with trimethylsilyl iodide to furnish supinidine ethyl ester 4 from which supinidine 5, isoretronecanol 7, and trachelanthamidine 9 were synthesized stereoselectively.