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Showing papers on "Resuscitation published in 1972"



Journal ArticleDOI
TL;DR: A definite prolongation of life was achieved in a productive age group of patients who were returned to their prior functional state in a general hospital, with an overall survival rate to discharge of 19.1 per cent.
Abstract: In one decade (1960–70), 1204 patients were resuscitated by a mobile team in a general hospital, with an overall survival rate to discharge of 19.1 per cent. In the 230 survivors, the survival rate was 74 per cent at one year, 59 per cent at two years and 51 per cent at three years. In the largest diagnostic group, coronary-artery disease, the survival rates were similar – i.e., 70 per cent, 55 per cent and 45 per cent at the end of the first, second and third years respectively. A random study of 15 per cent of the survivors showed that their functional capacity before and after resuscitation was unchanged. Half were under 60, and 80 per cent were under 70 years of age. A definite prolongation of life was thus achieved in a productive age group of patients who were returned to their prior functional state.

103 citations



Journal ArticleDOI
TL;DR: The records of 536 patients who required cardiorespiratory resuscitation during the period 1967-71 are reviewed and an outline of the system of resuscitation at present in operation in the Edinburgh Royal Infirmary is given.
Abstract: SUMMARY The records of 536 patients who required cardiorespiratory resuscitation during the period 1967-71 are reviewed. All suffered cardiac arrest and the results of treatment are expressed in terms of length of survival. 11.9% of cases were alive at one month, a favourable prognosis being associated with middle age, ventricular fibrillation as the primary electrocardiographic finding and conditions of a medical nature. Poor prognosis was associated with age under 40, electrocardiographic evidence of asystole and conditions of a surgical nature. An outline of the system of resuscitation at present in operation in the Edinburgh Royal Infirmary is given.

44 citations


Journal ArticleDOI
TL;DR: Methods to cool the brain rapidly during circulatory arrest in the experimental animal have been reviewed and emergency cephalic cooling, intra-arterial hypothermic infusion, direct ventricular perfusion cooling and carotid heat-exchanger interposition are reviewed.

23 citations





Journal ArticleDOI
01 Sep 1972-Heart
TL;DR: A five-bedded coronary care unit located in a general medical ward in a district general hospital has been subjected to a cost-benefit analysis and the results expressed in cost per life saved are suggested.
Abstract: A five-bedded coronary care unit located in a general medical ward in a district general hospital has been subjected to a cost-benefit analysis and the results expressed in costper life saved, assuming that the only benefit of the unit was resuscitation from cardiac arrest with survival to leave hospital. Direct costs were £320 per life saved. Indirect costs were also incurred because the existence of the unit resulted in the admission ofpatients who would otherwise have been treated at home, though this was mitigated by a reduction in mean length of stay during the first five years of the p unit's existence. Net indirect costs were £220 per life saved, giving a total cost of £540 per life saved. It is suggested that this kind of outcome analysis by survival could be used to assess the performance of other types of coronary care unit and of other forms of expensive medical treatment.

10 citations


Journal ArticleDOI
TL;DR: The ancient method of expired-air resuscitation, deeply rooted in Hebrew tradition, and sometimes referred to as the “Biblical Method,” was eclipsed by newer, less effective technics.
Abstract: HERE is nothing new under the sun.” “T (Ecclesiastes). Certainly the widespread application of intermittent positivepressure ventilation for resuscitation during the last 25 years represents merely the readaptation of a mode of treatment in use from time immemorial. Following the introduction in 1904 of Sir Edward SharpeySchafer’s technic for artificial respiration,l manual methods of ventilation constituted standard resuscitation practice for over 40 years, though the tilting or gravity method of Eve‘ also found a place in this sphere. The ancient method of expired-air resuscitation, deeply rooted in Hebrew tradition, and sometimes referred to as the “Biblical Method,” was eclipsed by newer, less effective technics.

8 citations


Journal ArticleDOI
TL;DR: It is concluded that the cyclopropane technique with barbiturate induction, and suxamethonium for intubation and muscle relaxation, is advantageous for patients in chronic renal failure.
Abstract: SUMMARY Cyclopropane anaesthesia was used in 100 patients requiring renal transplantation. This technique was found to provide cardiovascular stability. The incidence of hypotension was low (10 per cent) and could, in all instances, be related to blood loss. Hypertension followed reperfusion of the transplanted kidney in 8 patients, in 2 of which it was associated with cardiac arrhythmias. Induction with a short-acting barbiturate was responsible for one episode of hypotension. The use of suxamethonium for intubation and supplemental muscle relaxation even in hyperkalaemic patients caused no untoward effects. Cardiac arrest occurred during operation on one occasion; resuscitation was successful. It is concluded that the cyclopropane technique with barbiturate induction, and suxamethonium for intubation and muscle relaxation, is advantageous for patients in chronic renal failure.

Journal ArticleDOI
TL;DR: It is suggested that the response of the immature rat brain to asphyxia involves a disruption or increased fragility of lysosomal particles.
Abstract: 1. Five-day-old anaesthetized rats subjected to slow, prolonged asphyxia (50-55 min) were either allowed to die or resuscitated when at the point of death. Activities of various cerebral acid hydrolases known to be associated with lysosomes were determined in these animals and in littermate controls. 2. Asphyxia to death resulted in a significant increase in the activities of acid phosphatase, cathepsin (pH5.0) and beta-glucuronidase in whole-brain homogenates. 3. The effect of asphyxia on beta-glucuronidase activity was not apparent when the assay was performed in the presence of Triton X-100 (0.1%, v/v). 4. In resuscitated animals whole-brain-homogenate beta-glucuronidase activity showed the greatest increase (31%) 15 min after recovery. After a 60 min recovery period differences between control and asphyxiated animals were no longer apparent. 5. In animals anoxiated to death activities of acid phosphatase and beta-N-acetylglucosaminidase in brain high-speed supernatants were significantly higher than in controls. Acid phosphatase activity was similarly increased in asphyxiated animals resuscitated for 5 or 60 min. 6. It is suggested that the response of the immature rat brain to asphyxia involves a disruption or increased fragility of lysosomal particles.

Journal ArticleDOI
TL;DR: Twelve babies are described who were asphyxiated by profuse foam which formed in the airway after vigorous initial breaths and all recovered fully after resuscitation and none had subsequent breathing difficulties.


Journal ArticleDOI
TL;DR: The little-used technique of centripetal arterial blood transfusion is examined as an example of the difficulties facing resuscitation research in applying laboratory findings to the clinical situation.


Journal ArticleDOI
TL;DR: Rats anaesthetized and cooled to cardiac arrest had a hind-limb paralysis which recovered apparently completely in about 12 weeks, and had a permanent weight loss relative to controls.




Journal ArticleDOI
I.U. Degerli1
TL;DR: It is found that the most important aetiological factor in cardiac arrest is hypoxia or anoxia, arising from ventilatory problems, and to prevent cardiac arrest in surgery,Hypoxia and an oxia should be carefully avoided by the early treatment of respiratory insufficiency and the correction of hypovolaemia.



Journal ArticleDOI
TL;DR: An electronic system is described that distinguishes and tabulates pressure pulses received from the Resusci-Anne training mannequin during cardiopulmonary resuscitation (CPR).
Abstract: An electronic system is described that distinguishes and tabulates pressure pulses received from the Resusci-Anne training mannequin during cardiopulmonary resuscitation (CPR). The requirements of this system are in accordance with accepted CPR training programs. Samples of quantitative data gathered during mannequin practice sessions are included. The effectiveness of the system as a teaching aid is investigated, and correlations are made between CPR skills and a trainee's physical attributes.





Journal ArticleDOI
12 Jun 1972-JAMA
TL;DR: The initial experience with asanguineous hypothermic total body perfusion (total body washout or TBW) in the resuscitation of a patient dying of stage IV hepatic coma partial success served to teach to be more selective of future candidates and to make certain adjustments in the perfusate.
Abstract: To the Editor.— Recently we published an article citing our initial experience with asanguineous hypothermic total body perfusion (total body washout or TBW) in the resuscitation of a patient dying of stage IV hepatic coma. 1 The patient went on to die of Pseudomonas pneumonia which was present prior to the performance of the TBW. That partial success served to teach us to be more selective of future candidates and to make certain adjustments in our perfusate. These were done in our latest attempt to use the procedure in the care of a young airman dying of acute Australia antigen hepatitis. The airman had been ill and hospitalized for four weeks prior to transfer to our hospital. In the fifth week of his illness and in spite of intensive therapy with bowel antisepsis, steroids, and modified diet, he lapsed into a deepening coma. When received at our hospital, the patient

Journal ArticleDOI
TL;DR: A resuscitation trolley suitable for use in an emergency and accident department is described that offers full emergency facilities for circulatory and respiratory resuscitation and its mobility allows its use in any area of the department.
Abstract: A resuscitation trolley suitable for use in an emergency and accident department is described. It offers full emergency facilities for circulatory and respiratory resuscitation and its mobility allows its use in any area of the department.