Showing papers on "Swertia published in 2019"
TL;DR: In this paper, a microwave assisted extraction (MAE) using aqueous ethanol has been used to extract pentacyclic triterpenoids from Swertia chirata.
30 citations
TL;DR: In this article, a microwave-assisted extraction method coupled with simultaneous quantification of swertiamarin, amarogentin, and mangiferin from different species of Swertia using high performance thin layer chromatography (HPTLC) was developed.
26 citations
TL;DR: Information regarding the chemistry of amarogentin, its biological sources, bioavailability as a pharmacological agent for the treatment and management of skin disorders and various forms of cancers will be beneficial to the scientist of the medicinal field.
Abstract: There is a need for the development of liposomes based nanomedicines formulation for better efficacy and safety of the available drugs in the market. Liposomes have various applications in the field of pharmaceutical and medical field for their drug target potential, diagnostic importance and imaging techniques. Natural plant based drugs and their derivatives have been used in the medicine, nutraceuticals, perfumery, cosmetic and beverages industry. More than half of the prescribed drugs in the worldwide are mainly derived from different natural sources. Development of plant derived product is an emerging field of food, pharmaceutical and health industries. Plants belonging to the Gentianaecae family are well known for their bitter taste and Swertia chirata is one of best plants among them. Various active phytochemical of Swertia chirata are bitter secoiridoids like gentiopicroside, amarogentin, swertiamarin, isovitexin and isogentisin. People use different species of Swertia in the form of decoction, infusion, paste and juice for the treatment of fever and enteric diseases. Swertia chirata possesses anticarcinogenic, antioxidative, hypoglycemic, antihepatotoxic, antimalarial, anti-inflammatory and antimicrobial activities. Amarogentin, a bitter secoiridoid glycoside present in Swertia chirata plant is an activator of human bitter taste receptor. Pharmacologically, amarogentin has antibacterial, antihepatitis, anticholinergic and chemopreventive activities, moreover, amarogentin has been proven for their anti-lieshmanial activity. Other studies also suggested that amarogentin acts on liver carcinogenesis, skin carcinogenesis and reduced tumour progression. In the present review, we have collected and compiled the data regarding biological sources, ethnomedicinal uses, phytochemistry, anticancer and anti-infective potential of amarogentin. For better understanding of various aspects of amarogentin, we have also discussed Swertia chirayita in a very concise manner. Further data related to various patents on amarogentin have also been discussed in this manuscript. However, we also admit that new advance biological research will also increase the medicinal and pharmacological value of amarogentin. Information regarding the chemistry of amarogentin, its biological sources, bioavailability as a pharmacological agent for the treatment and management of skin disorders and various forms of cancers will be beneficial to the scientists in the medicinal field.
21 citations
TL;DR: The present review is to provide updated and comprehensive information on the genus Swertia, for promotin the development and uses of such ethnomedical resources, and elucidate its mechanisms of action as well as safety and toxicological assessment.
15 citations
TL;DR: Assessment of molecular and phytochemical diversity among 48 accessions of five Swertia species collected from Western Himalayas, India finds the potent S. chirata displays a low degree of genetic diversity and gene flow, and therefore there is a major risk of extinction of this significant species.
13 citations
TL;DR: UPLC fingerprint in association with chemometric tools provides a reliable and accurate quality assessment and detection of possible adulteration.
11 citations
TL;DR: Demethylbellidifolin was assigned as a mixed-type competitive inhibitor with the inhibiton constant Ki value of 6.87 µM by Lineweaver-Burk and slope plots and living cell imaging was conducted to corroborate its inhibitory HCE 2 activity.
10 citations
TL;DR: Swertia hongquanii Jia X. Li, a new species of Gentianaceae, is described and illustrated from Mt. Wuling, southern China and may be a member of series Maculatae.
Abstract: Swertia hongquanii Jia X. Li, a new species of Gentianaceae, is described and illustrated from Mt. Wuling, southern China. It grows on the tops of steep limestone mountains surrounded by cliffs above an altitude of ca. 1400 m. This species resembles Swertia bimaculata, but differs from the latter by the stem leaf blades 2.0-4.5 × 1.0-2.5 cm, ovate to ovate-cordate, base cordate and subamplexicaul, the seeds irregularly polyhedral and the seed coats minutely thorny and reticulate. Based on morphological traits, i.e. the inflorescence structure and the number and structure of the nectaries, the new species may be a member of series Maculatae. A key to the species of series of section MaculataeOphelia is provided.
1 citations
TL;DR: In this paper, strategies have been developed to optimize an efficient method for the swertia extraction in Indian Ayurvedic herbal systems and in Tibetan folk medicines to cure fever.
Abstract: Swertia is used in Indian Ayurvedic herbal systems and in Tibetan folk medicines to cure fever. In this investigation, strategies have been developed to optimize an efficient method for the...
1 citations
Patent•
15 Feb 2019
TL;DR: In this paper, a Jinsha swertia tea beverage capable of reliving a cough was described, which consists of the following raw materials in parts by weight of 60-70 parts of honeysuckle flowers, 1-2 parts of radix saussureae lappae, 5-8 parts of Jinshaswertia, 3-5 parts of lotus seeds, 1 2 parts of melon seed kernels, 005-01 part of ethyl maltol, 3 4 parts of platycodon roots, 01-02 part of
Abstract: The invention discloses a Jinsha swertia tea beverage capable of reliving cough The Jinsha swertia tea beverage consists of the following raw materials in parts by weight of 60-70 parts of honeysuckle flowers, 1-2 parts of radix saussureae lappae, 5-8 parts of Jinsha swertia, 3-5 parts of lotus seeds, 1-2 parts of melon seed kernels, 005-01 part of ethyl maltol, 3-4 parts of platycodon roots, 01-02 part of sodium stearoyl lactylate and 20-30 parts of cough-relieving liquid Loquat leaves and tendril-leaved fritillary bulb powder are used as raw materials, and an extracting solution is performed The extracting solution has good effects of relieving a cough and nourishing the lung Enzymolysis is performed with hemicellulases, so that the content of sugar is increased, the mouth feel of the finished products tea beverage is improved, and the nutrient value is increased
Journal Article•
Patent•
03 Dec 2019
TL;DR: In this paper, an artificial high-efficiency propagation method for swertia kauitchensis franch is presented, which is low in cost, short in time, considerable in reproduction coefficient, and high in quality and survival rate.
Abstract: The invention discloses an artificial high-efficiency propagation method for swertia kauitchensis franch. The method includes the steps that explants with nodal stem segments after disinfection and sterilization treatment are subjected to callus induction, basal stem cluster bud generation and proliferation, vitrification phenomenon overcoming, adventitious root induction, and domestication and transplanting. By adopting the artificial high-efficiency propagation method for swertia kauitchensis franch, the problems that variation during traditional sexual reproduction of swertia plants is excessive while a vitrification phenomenon is likely to occur during asexual reproduction and the like are solved, and the artificial high-efficiency propagation method for swertia kauitchensis franch islow in cost, short in time, considerable in reproduction coefficient, and high in quality and survival rate.