A
A. Di Pietro
Researcher at University of Lyon
Publications - 51
Citations - 1402
A. Di Pietro is an academic researcher from University of Lyon. The author has contributed to research in topics: Medicine & ATPase. The author has an hindex of 21, co-authored 37 publications receiving 1293 citations. Previous affiliations of A. Di Pietro include Centre national de la recherche scientifique & Claude Bernard University Lyon 1.
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Journal ArticleDOI
Modulation by flavonoids of cell multidrug resistance mediated by P-glycoprotein and related ABC transporters.
A. Di Pietro,G. Conseil,José M. Pérez-Victoria,G. Dayan,Hélène Baubichon-Cortay,Doriane Trompier,Emmanuelle Steinfels,Jean-Michel Jault,H de Wet,Mathias Maitrejean,Gilles Comte,Ahcène Boumendjel,Anne-Marie Mariotte,Charles Dumontet,David B. McIntosh,André Goffeau,Santiago Castanys,Francisco Gamarro,Denis Barron +18 more
TL;DR: This review shows that due to similarities in function and maybe in three-dimensional organization of the different transporters, common potential modulators have been found and constitute promising potentialmodulators of multidrug resistance.
Journal ArticleDOI
Multidrug resistance phenotype mediated by the P-glycoprotein-like transporter in Leishmania: a search for reversal agents.
José M. Pérez-Victoria,A. Di Pietro,D. Barron,Angel G. Ravelo,Santiago Castanys,Francisco Gamarro +5 more
TL;DR: A rational strategy developed to overcome the MDR phenotype in Leishmania, including the resistance to the most promising new antileishmania agents, the alkyl-lysophospholipids is reviewed.
Journal ArticleDOI
Overexpression and purification of the carboxyl-terminal nucleotide-binding domain from mouse P-glycoprotein. Strategic location of a tryptophan residue.
TL;DR: The results put forward a functional role for the tryptophan-containing sequence of P-glycoprotein NBD2 that was not detected up to now and potentially prevented or chased by ATP or ADP at millimolar concentrations.
Journal ArticleDOI
Jatrophane diterpenes from Euphorbia spp. as modulators of multidrug resistance in cancer therapy
Gabriella Corea,A. Di Pietro,Charles Dumontet,Charles Dumontet,Ernesto Fattorusso,Virginia Lanzotti +5 more
TL;DR: A phytochemical investigation of the aerial parts of Euphorbia spp.
Journal ArticleDOI
Multiple flavonoid-binding sites within multidrug resistance protein MRP1.
Doriane Trompier,Hélène Baubichon-Cortay,Xiu Bao Chang,Mathias Maitrejean,Denis Barron,J. R. Riordan,A. Di Pietro +6 more
TL;DR: The overall results indicate multiple binding sites for dehydrosilybin and its derivatives, on both cytosolic and transmembrane domains of MRP1.